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  1. Association of glutathione-S-transferase polymorphism with genetic damage in paint workers

    Background

    Occupational exposure to toluene causes serious health problems ranging from drowsiness to lethal diseases such as cancer. Paint workers...

    KanuPriya, Sunil Kumar, ... Anita Yadav in Molecular Biology Reports
    Article 18 April 2023
  2. The glutathione S-transferase Gstt1 drives survival and dissemination in metastases

    Identifying the adaptive mechanisms of metastatic cancer cells remains an elusive question in the treatment of metastatic disease, particularly in...

    Christina M. Ferrer, Hyo Min Cho, ... Raul Mostoslavsky in Nature Cell Biology
    Article 11 June 2024
  3. Glutathione S-transferase activity facilitates rice tolerance to the barnyard grass root exudate DIMBOA

    Background

    In paddy fields, the noxious weed barnyard grass secretes 2,4-dihydroxy-7-methoxy-2 H -1,4-benzoxazin-3(4 H )-one (DIMBOA) to interfere with...

    Huabin Zhang, Dan Mu, ... Changxun Fang in BMC Plant Biology
    Article Open access 17 February 2024
  4. Detection of Protein–Protein Interactions Using Glutathione-S-Transferase (GST) Pull-Down Assay Technique

    Pull-down assay is a technique to analyze direct protein–protein interaction under in vitro condition. Also, this technique is appropriate for...
    Prabu Gnanasekaran, Hanu R. Pappu in Protein-Protein Interactions
    Protocol 2023
  5. Investigation of Potential Effects of Some Indole Compounds on the Glutathione S-Transferase Enzyme

    Abstract

    Glutathione S-transferases (GSTs) belong to the superfamily of multifunctional detoxification isoenzymes with an important role in cellular...

    Muhammet Serhat Özaslan in Biochemistry (Moscow)
    Article 01 March 2024
  6. The importance of polymorphisms in the genes encoding glutathione S-transferase isoenzymes in development of selected cancers and cardiovascular diseases

    Glutathione S-transferases are a family of enzymes, whose main role is to detoxify cells from many exogenous factors, such as xenobiotics or...

    Katarzyna Grussy, Magdalena Łaska, ... Milena Ściskalska in Molecular Biology Reports
    Article Open access 11 October 2023
  7. Isolation and characterization of glutathione S-transferase genes and their transcripts in Saccharina japonica (Laminariales, Phaeophyceae) during development and under abiotic stress

    Background

    Glutathione S-transferase (GST) is a crucial enzyme for metabolism, detoxification, and stress resistance in organisms. Many GSTs have been...

    Chang Lu, Pengyan Zhang, ... Delin Duan in BMC Plant Biology
    Article Open access 18 September 2023
  8. Glutathione S-transferase Mu 2 inhibits hepatic steatosis via ASK1 suppression

    Hepatic steatosis is the main characteristic of some liver metabolism diseases. However, unclear molecular mechanism of hepatic steatosis impedes the...

    Yi **, Yanjie Tan, ... Zhuqing Ren in Communications Biology
    Article Open access 06 April 2022
  9. Functional Analysis of the Anthocyanin-Associated Glutathione S-Transferase Gene StGST1 in Potato

    Anthocyanins are biosynthesized on the cytoplasmic surface of the endoplasmic reticulum and then transported to the vacuole for storage. Glutathione S ...

    Zhonghua Zhang, Huiling Zhang, ... Ju** Zhang in Potato Research
    Article 17 August 2022
  10. Discovery of potent inhibitors targeting Glutathione S-transferase of Wuchereria bancrofti: a step toward the development of effective anti-filariasis drugs

    Lymphatic filariasis (LF) is one of the major health problems for the human kind in develo** countries including India. LF is caused by three major...

    Muthusamy Sureshan, Dhamodharan Prabhu, ... Kadhirvel Saraboji in Molecular Diversity
    Article 16 February 2023
  11. Higher activity of Glutathione S-transferase enzyme is associated with field evolved resistance in Empoasca flavescens Fabricius

    Empoasca flavescens Fabricius is one of the most important sucking pests of tea. Earlier this pest was considered as minor pest of tea. But this has...

    Biswajit Patra, Somnath Mandal, ... Tapan Kumar Hath in International Journal of Tropical Insect Science
    Article 25 May 2022
  12. Computational insights into diverse aspects of glutathione S-transferase gene family in Papaver somniferum

    Plant glutathione S-transferases are an ancient protein superfamily having antioxidant activity. These proteins are primarily involved in diverse...

    Swati Vaish, Reshma Parveen, ... Mahesh Kumar Basantani in Journal of Plant Research
    Article 06 September 2022
  13. Genetic polymorphism of lysyl oxidase, glutathione S-transferase M1, glutathione-S-transferase T1, and glutathione S-transferase P1 genes as risk factors for lung cancer in Egyptian patients

    Lung cancer is a lethal malignancy and is affected by genetic polymorphisms that contribute to an individual’s susceptibility to develo** the...

    Sahar E. M. El-Deek, Soad M. Abdel-Ghany, ... Ayat A. Sayed in Molecular Biology Reports
    Article 30 May 2021
  14. Genome-Wide Analysis of Glutathione S-Transferase Gene Family in P. vulgaris Under Drought and Salinity Stress

    The enzymes known as glutathione S-transferases (GST), which are present in many evolved organisms, are essential for the defense against reactive...

    Selman Muslu, Ayşe Gül Kasapoğlu, ... Murat Aydın in Plant Molecular Biology Reporter
    Article 28 July 2023
  15. Genetic map**, transcriptomic sequencing and metabolic profiling indicated a glutathione S-transferase is responsible for the red-spot-petals in Gossypium arboreum

    Key message

    A GST for red-spot-petals in Gossypium arboreum was identified as the candidate under the scope of multi-omics approaches.

    ...
    Sujun Zhang, Jie Chen, ... Jianhong Zhang in Theoretical and Applied Genetics
    Article 19 August 2022
  16. Molecular action of larvicidal flavonoids on ecdysteroidogenic glutathione S-transferase Noppera-bo in Aedes aegypti

    Background

    Mosquito control is a crucial global issue for protecting the human community from mosquito-borne diseases. There is an urgent need for the...

    Kazue Inaba, Kana Ebihara, ... Ryusuke Niwa in BMC Biology
    Article Open access 17 February 2022
  17. Glutathione S-transferase A2 promotes hepatocellular carcinoma recurrence after liver transplantation through modulating reactive oxygen species metabolism

    Hepatocellular carcinoma (HCC) recurrence after liver transplantation remains a significant clinical problem. Ischemia-reperfusion injury (IRI)...

    Kevin Tak-Pan Ng, Oscar Wai-Ho Yeung, ... Kwan Man in Cell Death Discovery
    Article Open access 21 July 2021
  18. Overexpression of the Glutathione S-Transferase ATGSTF11 Gene Improves Growth and Abiotic Stress Tolerance of Tobacco Transgenic Plants

    Abstract

    Genes encoding glutathione S-transferases (GSTs) are potential targets for creating stress-tolerant plants by genetic engineering techniques....

    B. R. Kuluev, A. A. Ermoshin, E. V. Mikhaylova in Russian Journal of Plant Physiology
    Article 01 December 2022
  19. State of Antioxidant System and Long-Term Storage of Tobacco Hairy Roots with Constitutive Expression of Glutathione-S-Transferase Gene ATGSTF11

    Abstract

    One of the pressing tasks of current biotechnology is the production of stress-resistant cultures of hairy roots and elaboration of...

    Kh. G. Musin, V. V. Fedyaev, B. R. Kuluev in Russian Journal of Plant Physiology
    Article 10 July 2021
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