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Association of glutathione-S-transferase polymorphism with genetic damage in paint workers
BackgroundOccupational exposure to toluene causes serious health problems ranging from drowsiness to lethal diseases such as cancer. Paint workers...
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The glutathione S-transferase Gstt1 drives survival and dissemination in metastases
Identifying the adaptive mechanisms of metastatic cancer cells remains an elusive question in the treatment of metastatic disease, particularly in...
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Glutathione S-transferase activity facilitates rice tolerance to the barnyard grass root exudate DIMBOA
BackgroundIn paddy fields, the noxious weed barnyard grass secretes 2,4-dihydroxy-7-methoxy-2 H -1,4-benzoxazin-3(4 H )-one (DIMBOA) to interfere with...
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Detection of Protein–Protein Interactions Using Glutathione-S-Transferase (GST) Pull-Down Assay Technique
Pull-down assay is a technique to analyze direct protein–protein interaction under in vitro condition. Also, this technique is appropriate for... -
Investigation of Potential Effects of Some Indole Compounds on the Glutathione S-Transferase Enzyme
AbstractGlutathione S-transferases (GSTs) belong to the superfamily of multifunctional detoxification isoenzymes with an important role in cellular...
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The importance of polymorphisms in the genes encoding glutathione S-transferase isoenzymes in development of selected cancers and cardiovascular diseases
Glutathione S-transferases are a family of enzymes, whose main role is to detoxify cells from many exogenous factors, such as xenobiotics or...
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Isolation and characterization of glutathione S-transferase genes and their transcripts in Saccharina japonica (Laminariales, Phaeophyceae) during development and under abiotic stress
BackgroundGlutathione S-transferase (GST) is a crucial enzyme for metabolism, detoxification, and stress resistance in organisms. Many GSTs have been...
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Glutathione S-transferase Mu 2 inhibits hepatic steatosis via ASK1 suppression
Hepatic steatosis is the main characteristic of some liver metabolism diseases. However, unclear molecular mechanism of hepatic steatosis impedes the...
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Functional Analysis of the Anthocyanin-Associated Glutathione S-Transferase Gene StGST1 in Potato
Anthocyanins are biosynthesized on the cytoplasmic surface of the endoplasmic reticulum and then transported to the vacuole for storage. Glutathione S ...
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Discovery of potent inhibitors targeting Glutathione S-transferase of Wuchereria bancrofti: a step toward the development of effective anti-filariasis drugs
Lymphatic filariasis (LF) is one of the major health problems for the human kind in develo** countries including India. LF is caused by three major...
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Higher activity of Glutathione S-transferase enzyme is associated with field evolved resistance in Empoasca flavescens Fabricius
Empoasca flavescens Fabricius is one of the most important sucking pests of tea. Earlier this pest was considered as minor pest of tea. But this has...
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Computational insights into diverse aspects of glutathione S-transferase gene family in Papaver somniferum
Plant glutathione S-transferases are an ancient protein superfamily having antioxidant activity. These proteins are primarily involved in diverse...
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Genetic polymorphism of lysyl oxidase, glutathione S-transferase M1, glutathione-S-transferase T1, and glutathione S-transferase P1 genes as risk factors for lung cancer in Egyptian patients
Lung cancer is a lethal malignancy and is affected by genetic polymorphisms that contribute to an individual’s susceptibility to develo** the...
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Genome-Wide Analysis of Glutathione S-Transferase Gene Family in P. vulgaris Under Drought and Salinity Stress
The enzymes known as glutathione S-transferases (GST), which are present in many evolved organisms, are essential for the defense against reactive...
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Synthesis and characterization of novel bis(thiosemicarbazone) complexes and investigation of their acetylcholinesterase and glutathione S-transferase activities with in silico and in vitro studies
In this study, firstly, bis(thiosemicarbazone) ligand [L:...
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Genetic map**, transcriptomic sequencing and metabolic profiling indicated a glutathione S-transferase is responsible for the red-spot-petals in Gossypium arboreum
Key messageA GST for red-spot-petals in Gossypium arboreum was identified as the candidate under the scope of multi-omics approaches.
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Molecular action of larvicidal flavonoids on ecdysteroidogenic glutathione S-transferase Noppera-bo in Aedes aegypti
BackgroundMosquito control is a crucial global issue for protecting the human community from mosquito-borne diseases. There is an urgent need for the...
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Glutathione S-transferase A2 promotes hepatocellular carcinoma recurrence after liver transplantation through modulating reactive oxygen species metabolism
Hepatocellular carcinoma (HCC) recurrence after liver transplantation remains a significant clinical problem. Ischemia-reperfusion injury (IRI)...
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Overexpression of the Glutathione S-Transferase ATGSTF11 Gene Improves Growth and Abiotic Stress Tolerance of Tobacco Transgenic Plants
AbstractGenes encoding glutathione S-transferases (GSTs) are potential targets for creating stress-tolerant plants by genetic engineering techniques....
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State of Antioxidant System and Long-Term Storage of Tobacco Hairy Roots with Constitutive Expression of Glutathione-S-Transferase Gene ATGSTF11
AbstractOne of the pressing tasks of current biotechnology is the production of stress-resistant cultures of hairy roots and elaboration of...