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Functional Enrichment Analysis Identifying Regulatory Information Associated with Human Fracture
Dozens of loci associated with fracture have been identified by genome-wide association studies (GWASs). However, most of these variants are located...
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vissE: a versatile tool to identify and visualise higher-order molecular phenotypes from functional enrichment analysis
Functional analysis of high throughput experiments using pathway analysis is now ubiquitous. Though powerful, these methods often produce thousands...
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Trait-dependent importance of intraspecific variation relative to species turnover in determining community functional composition following nutrient enrichment
Community weighted mean trait, i.e., functional composition, has been extensively used for upscaling of individual traits to the community functional...
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Regulatory landscape enrichment analysis (RLEA): a computational toolkit for non-coding variant enrichment and cell type prioritization
BackgroundAs genomic studies continue to implicate non-coding sequences in disease, testing the roles of these variants requires insights into the...
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Experimental nutrient enrichment increases plankton taxonomic and functional richness and promotes species dominance overtime
In this study, we have shown that nutrient input in aquatic ecosystems has different impacts on the various facets of phytoplankton and zooplankton...
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Functional traits to predict financial value of enrichment planting in degraded tropical forests
Demand for tropical timber is expected to rise due to an increased global need for sustainable renewable materials. However, sustainable tropical...
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ALGAEFUN with MARACAS, microALGAE FUNctional enrichment tool for MicroAlgae RnA-seq and Chip-seq AnalysiS
BackgroundMicroalgae are emerging as promising sustainable sources for biofuels, biostimulants in agriculture, soil bioremediation, feed and human...
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Potato Peel Enrichment in Functional Food and Feed
The potato is the fourth most common crop cultivated globally every year. Potato peel is the major waste released by potato-processing industries and...
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Construction and functional enrichment analysis of the competitive endogenous RNA regulatory network for nonarteritic anterior ischemic optic neuropathy based on high-throughput sequencing
Based on the transcriptome high-throughput sequencing of nonarteritic anterior ischemic optic neuropathy (NAION), this study constructed a...
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Biclustering for Epi-Transcriptomic Co-functional Analysis
Dynamic and reversible N6-methyladenosine (m6A) modifications are associated with many essential cellular functions as well as physiological and...
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13C Isotope Labeling and Mass Spectrometric Isotope Enrichment Analysis in Acute Brain Slices
Feeding of stable 13C-labeled compounds coupled to mass spectrometric analysis has enabled the characterization of dynamic metabolite partitioning in...
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Roastgsa: a comparison of rotation-based scores for gene set enrichment analysis
BackgroundGene-wise differential expression is usually the first major step in the statistical analysis of high-throughput data obtained from...
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Streamlined Biotinylation, Enrichment and Analysis for Enhanced Plasma Membrane Protein Identification Using TurboID and TurboID-Start Biotin Ligases
Plasma membrane proteins (PMPs) play pivotal roles in various cellular events and are crucial in disease pathogenesis, making their comprehensive...
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PIGNON: a protein–protein interaction-guided functional enrichment analysis for quantitative proteomics
BackgroundQuantitative proteomics studies are often used to detect proteins that are differentially expressed across different experimental...
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Multi-omics analysis of functional substances and expression verification in cashmere fineness
BackgroundNumerous factors influence the growth and development of cashmere. Existing research on cashmere has predominantly emphasized a single...
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Endothelial Cell RNA-Seq Data: Differential Expression and Functional Enrichment Analyses to Study Phenotypic Switching
RNA-seq is a common approach used to explore gene expression data between experimental conditions or cell types and ultimately leads to information...
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Single-nucleus analysis reveals microenvironment-specific neuron and glial cell enrichment in Alzheimer’s disease
BackgroundAlzheimer’s disease (AD) is a complicated neurodegenerative disease. Neuron-glial cell interactions are an important but not fully...
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DhuFAP: a platform for gene functional analysis in Dendrobium huoshanense
BackgroundDendrobium huoshanense , a traditional medicinal and food plant, has a rich history of use. Recently, its genome was decoded, offering...
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GOAT: efficient and robust identification of gene set enrichment
Gene set enrichment analysis is foundational to the interpretation of high throughput biology. Identifying enriched Gene Ontology (GO) terms or...
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SEMgsa: topology-based pathway enrichment analysis with structural equation models
BackgroundPathway enrichment analysis is extensively used in high-throughput experimental studies to gain insight into the functional roles of...
