Search
Search Results
-
Flavin-Dependent Dehydrogenases and Oxidases: Comparison of Structural Functional Properties (A Review)
AbstractFlavin-dependent dehydrogenases and oxidases are enzymes that play an important role in living organisms and are widely used in practice....
-
Alteration of Flavin Cofactor Homeostasis in Human Neuromuscular Pathologies
The aim of this short review chapter is to provide a brief summary of the relevance of riboflavin (Rf or vitamin B2) and its derived cofactors flavin...
-
Structures and Electron Transport Paths in the Four Families of Flavin-Based Electron Bifurcation Enzymes
Oxidoreductases facilitating electron transfer between molecules are pivotal in metabolic pathways. Flavin-based electron bifurcation (FBEB), a...
-
Recent Advances in Construction of the Efficient Producers of Riboflavin and Flavin Nucleotides (FMN, FAD) in the Yeast Candida famata
The approaches used by the authors to design the Candida famata strains capable to overproduce riboflavin, flavin mononucleotide (FMN), and flavin...
-
MSMEG_3955 from Mycobacterium smegmatis is a FMN bounded homotrimeric NAD(P)H:Flavin mononucleotide (FMN) oxidoreductase
BackgroundTuberculosis (TB) remains an important public health problem since it is the major cause of elevated morbidity and mortality globally....
-
-
Omics analysis of Mycobacterium tuberculosis isolates uncovers Rv3094c, an ethionamide metabolism-associated gene
Global control of the tuberculosis epidemic is threatened by increasing prevalence of drug resistant M. tuberculosis isolates. Many genome-wide...
-
An isoform-specific pivot modulates the electron transfer between the flavin mononucleotide and heme centers in inducible nitric oxide synthase
Intraprotein interdomain electron transfer (IET) between the flavin mononucleotide (FMN) and heme centers is an obligatory step in nitric oxide...
-
Flavin-mediated reductive iron mobilization from frog M and Mycobacterial ferritins: impact of their size, charge and reactivities with NADH/O2
In vitro, reductive mobilization of ferritin iron using suitable electron transfer mediators has emerged as a possible mechanism to mimic the iron...
-
Antimicrobial Photodynamic Activity of Hydrophilic Riboflavin Derivatives
The aim of this work was to investigate the antibacterial and antiviral properties of a riboflavin derivative (Vitamin B2), flavin mononucleotide and...
-
Interceptor potential of C60 fullerene aqueous solution: a comparative analysis using the example of the antitumor antibiotic mitoxantrone
We performed a qualitative and quantitative analysis of intermolecular interactions in aqueous solution between the antitumor antibiotic mitoxantrone...
-
Continuous and Discontinuous Approaches to Study FAD Synthesis and Degradation Catalyzed by Purified Recombinant FAD Synthase or Cellular Fractions
Riboflavin, or vitamin B2, is the precursor of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), essential redox (and sometimes...
-
Structural and functional characterization of a new thermophilic-like OYE from Aspergillus flavus
AbstractOld yellow enzymes (OYEs) have been proven as powerful biocatalysts for the asymmetric reduction of activated alkenes. Fungi appear to be...
-
Preparing Modified Hyaluronic Acid with Tunable Content of Vinyl Groups for Use in Fabrication of Scaffolds by Photoinduced Crosslinking
AbstractMaterials based on hyaluronic acid (HA) are extensively used in tissue engineering as scaffolds. Photoinduced crosslinking is one way to...
-
Upregulation of SLC25A32 in Tumorous Tissues of Patients with Non-Metastatic Colorectal Cancer: A Pilot Study
The SLC25A32 gene plays a pivotal regulatory role in one-carbon metabolism and redox balance by functioning as a transporter for tetrahydrofolate and...
-
Photochemistry and Signaling Activity of Plant Cryptochromes: A Review
Abstract —Cryptochromes constitute an extensive class of blue-light sensory receptors that regulate the processes of development and circadian rhythm...
-
On Katsuko Kakinuma: Spectroscopic Studies of Redox Centers in NADPH Oxidase – “Identifying and Observing the Key Players that Pass an Electron to Oxygen”
Dr. Katsuko Kakinuma made many important contributions to biology and medicine through the study of the neutrophil NADPH oxidase system, particularly...
-
The In Vitro Production of prFMN for Reconstitution of UbiD Enzymes
Prenylated flavin (prFMN) is a modified FMN cofactor, the isoalloxazine is extended by an additional six membered nonaromatic ring. The modification...
-
Multispectral autofluorescence characteristics of reproductive aging in old and young mouse oocytes
Increasing age has a major detrimental impact on female fertility, which, with an ageing population, has major sociological implications. This impact...
-
Sugarcane ScOPR1 gene enhances plant disease resistance through the modulation of hormonal signaling pathways
Key messageTransgenic plants stably overexpressing ScOPR1 gene enhanced disease resistance by increasing the accumulation of JA, SA, and GST, as...
