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Cytotoxicity Assay
Cytotoxicity test is defined as the screening test and biological evaluation of tissue cells in vitro to detect the growth, the reproduction, and...
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Neutral Red Uptake Assay to Assess Cytotoxicity In Vitro
The neutral red uptake (NRU) assay is a cell viability assay that can be used for the assessment of compound-induced cytotoxicity. It is based on the...
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Cytotoxicity Studies of 5-Arylaminouracil Derivatives
AbstractWe have previously shown that 5-arylaminouracil derivatives can inhibit HIV-1, herpesviruses, mycobacteria, and other pathogens through...
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Assessment of Cell Cytotoxicity in 3D Biomaterial Scaffolds Following miRNA Transfection
Assessment of cell cytotoxicity following transfection of cells with microRNA (miRNA) is an essential step in the evaluation of basic miRNA...
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In Vitro Cytotoxicity Analysis: MTT/XTT, Trypan Blue Exclusion
In vitro cytotoxicity analyses have played a major role in the current drug discovery processes. These analyses enable the measurement of target cell...
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TMRM Cytotoxicity Assay
Mitochondrial functioning is a vital parameter to assess cellular health. It produces energy as ATP molecules by oxidative phosphorylation through an...
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Three-Dimensional Hanging Drop Spheroid Plates for Easy Chimeric Antigen Receptor (CAR) T Cytotoxicity Assay
Chimeric antigen receptor (CAR) T cell therapy shows a highly effective therapeutic effect on B-cell malignancies. The tumor microenvironment (TME)...
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Cytotoxicity Models in Chromaffin Cells to Evaluate Neuroprotective Compounds
Primary cultures of bovine chromaffin cells are considered a good model to evaluate potential neuroprotective compounds for two major reasons: (i)...
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Semi-synthesis and structure-activity relationship study yield antibacterial vicenistatin derivatives with low cytotoxicity
Vicenistatin ( 1 ) is a 20-membered polyketide macrocyclic antibiotic with potent antimicrobial and cytotoxic activities. In this study, to further...
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Cytotoxicity-reducing and anti-inflammatory effects of a natural herb mixture extract
BackgroundNatural herb mixture extracts have been used in traditional medicine in many countries for several years and are currently widely used as...
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Investigating the antimicrobial activity, cytotoxicity, and action mechanism of acylated and amidated derivatives of AurH1 antifungal peptide
BackgroundThe increasing growth of microbial resistance threatens the health of human societies. Therefore, the discovery and design of new...
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Vismodegib Potentiates Marine Antimicrobial Peptide Tilapia Piscidin 4-Induced Cytotoxicity in Human Non-Small Cell Lung Cancer Cells
Non-small cell lung cancer (NSCLC) is a common cancer with several accepted treatments, such as chemotherapy, epidermal growth factor receptor (EGFR)...
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MiR-30c facilitates natural killer cell cytotoxicity to lung cancer through targeting GALNT7
BackgroundMicroRNAs (miRNAs) have been reported to play important roles in regulating natural killer (NK) cell cytotoxicity to cancer cells.
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Iron-induced cytotoxicity mediated by endolysosomal TRPML1 channels is reverted by TFEB
Increased brain iron content has been consistently reported in sporadic Parkinson’s disease (PD) patients, and an increase in cytosolic free iron is...
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Impact of Time and Enzyme Concentration on Sangyod Rice Bran Hydrolysate: Phytochemicals, Antioxidants, Amino Acids, and Cytotoxicity
This study investigated the production of Sangyod rice bran hydrolysate (SYRB) from Sangyod rice, focusing on incubation times (1, 3, and 5 h) and...
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Glycyrrhinic acid and probiotics alleviate deoxynivalenol-induced cytotoxicity in intestinal epithelial cells
Deoxynivalenol (DON) is one of the most prevalent mycotoxin contaminants, which posing a serious health threat to animals and humans. Previous...
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Characterization and cytotoxicity assessment of cadmium sulfide quantum dots synthesized with Fusarium oxysporum f. sp. lycopersici
The potential of CdS quantum dots for biomedical and bioimaging applications depends on their cytotoxicity, which can be modulated by coating...
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Increasing the radiation-induced cytotoxicity by silver nanoparticles and docetaxel in prostate cancer cells
BackgroundRadiation therapy is utilized for treatment of localized prostate cancer. Nevertheless, cancerous cells frequently develop radiation...
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Long chain capsaicin analogues synthetized by CALB-CLEAs show cytotoxicity on glioblastoma cell lines
AbstractGlioblastoma is one of the most lethal tumors, displaying striking cellular heterogeneity and drug resistance. The prognosis of patients...
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Evaluation of Anti-endotoxin Activity, Hemolytic Activity, and Cytotoxicity of a Novel Designed Peptide: An In Silico and In Vitro Study
Endotoxin, also identified as lipopolysaccharide (LPS), is considered the pathogenic factor of septic shock triggered by Gram-negative bacteria and...
