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Diverse functions of cytochrome c in cell death and disease
The redox-active protein cytochrome c is a highly positively charged hemoglobin that regulates cell fate decisions of life and death. Under normal...
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Peculiarities of Cytochrome c Enzymatic Activity with Cardiolipin
AbstractThe points of enzymatic activity, quantum yields, structure, functions of luminol chemiluminescence activated by physical activators natural...
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Pirh2 modulates the mitochondrial function and cytochrome c-mediated neuronal death during Alzheimer’s disease
Pirh2 is an E3 ubiquitin ligase known to regulate the DNA damage responses through ubiquitylation of various participating signaling factors. DNA...
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Altered conformational dynamics contribute to species-specific effects of cytochrome c mutations on caspase activation
Variants in the gene encoding human cytochrome c ( CYCS ) cause mild autosomal dominant thrombocytopenia. Despite high sequence conservation between...
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Assay of Endocannabinoid Oxidation by Cytochrome P450
Cytochrome P450 enzymes are a large family of heme-containing proteins that have important functions in the biotransformation of xenobiotics,...
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Cytochrome bd as Antioxidant Redox Enzyme
AbstractOne of the main functions of enzyme complexes that constitute electron transport (respiratory) chains of organisms is to maintain cellular...
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Mining and functional characterization of NADPH-cytochrome P450 reductases of the DNJ biosynthetic pathway in mulberry leaves
Background1-Deoxynojirimycin (DNJ), the main active ingredient in mulberry leaves, with wide applications in the medicine and food industries due to...
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Role of Cytochrome P450 in Xenobiotic Metabolism in Fishes (Review)
Cytochrome P450 (CYP) enzymes encompass a family of heme proteins which plays a prime role in the biotransformation of broad range of exogenous and...
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Cytochrome P450 for environmental remediation: catalytic mechanism, engineering strategies and future prospects
Environmental pollution is a global concern. Various organic compounds are released into the environment through wastewater, waste gas, and waste...
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Drop-casted Photosystem I/cytochrome c multilayer films for biohybrid solar energy conversion
One of the main barriers to making efficient Photosystem I-based biohybrid solar cells is the need for an electrochemical pathway to facilitate...
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Concerning the enigmatic cytochrome b-559 of oxygenic photosynthesis
Although there is an extensive literature on the properties and possible electron transfer pathways of cytochrome b -559, which is a prominent subunit...
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Mitochondria and cytochrome components released into the plasma of severe COVID-19 and ICU acute respiratory distress syndrome patients
IntroductionProteomic analysis of human plasma by LC–ESI–MS/MS has discovered a limited number of new cellular protein biomarkers that may be...
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Cytochrome-c-oxidase and ATPsynthase content increases in the endometrium of the patients with adenomyosis
BackgroundAdenomyosis is characterized by overgrowth of endometrial glands and stroma in the myometrium and is associated with reduced apoptosis. One...
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Recent insights into function, structure and modification of cytochrome P450 153 a family
Cytochrome P450 153 A (CYP153A) is a versatile enzyme that can catalyze a wide range of oxidation reactions on various substrates. This review...
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Chlorophyll a Dimers Bound in the Water-Soluble Protein BoWSCP Photosensitize the Reduction of Cytochrome c
AbstractWhen bound to water-soluble proteins of the WSCP family, chlorophyll molecules form dimers structurally similar to the “special pair” of...
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Analysis of substrate specificity of cytochrome P450 monooxygenases involved in trichothecene toxin biosynthesis
Trichothecenes are a structurally diverse family of toxic secondary metabolites produced by certain species of multiple fungal genera. All...
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The role of cytochrome P450 3A2 and 4V2 in response to high-temperature stress in Tetranychus truncatus (Acari: Tetranychidae)
Temperature is an important factor influencing the physiological activities of agricultural pests. Therefore, understanding pest physiological...
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Plant cytochrome P450s directing monoterpene indole alkaloid (MIA) and benzylisoquinoline alkaloid (BIA) biosynthesis
The large family of cytochrome P450 enzymes are heme containing proteins generally associated with the cytoplasmic face of the endoplasmic reticulum...
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Development of Mutant Forms of Neuroglobin with Substitutions in the Interaction Surface with Cytochrome c
AbstractMutant forms of human neuroglobin that carry targeted mutations in the putative interface with cytochrome c : single (E60K, K67E, E87K, K95E)...
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Cryo-EM structure of an extracellular Geobacter OmcE cytochrome filament reveals tetrahaem packing
Electrically conductive appendages from the anaerobic bacterium Geobacter sulfurreducens were first observed two decades ago, with genetic and...
