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Microbial Production of Curcumin
Curcumin, a polyphenol produced by turmeric (Curcuma longa), has attracted increased attention due to its potential as a novel cancer-fighting drug.... -
Curcumin and Ferroptosis: a Promising Target for Disease Prevention and Treatment
Ferroptosis is a recently identified form of cell death characterized by iron accumulation and lipid peroxidation. Unlike apoptosis, necrosis, and...
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Longevity and anti-aging effects of curcumin supplementation
Aging is a gradual and irreversible process that is accompanied by an overall decline in cellular function and a significant increase in the risk of...
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Oxidative Stress-Induced Platelet Apoptosis/Activation: Alleviation by Purified Curcumin via ASK1-JNK/p-38 Pathway
AbstractPlatelets are known for their indispensable role in hemostasis and thrombosis. However, alteration in platelet function due to oxidative...
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Curcumin leads to responses of grapes to aluminum stress by inducing whole genome hypo-methylation
Aluminum (Al) is the most abundant element in the earth crust. Due to the abuse of phosphate fertilizer, acid rain has been frequently observed in...
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Curcumin alleviates AFB1-induced nephrotoxicity in ducks: regulating mitochondrial oxidative stress, ferritinophagy, and ferroptosis
Aflatoxin B1 (AFB1), an extremely toxic mycotoxin that extensively contaminates feed and food worldwide, poses a major hazard to poultry and human...
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Protective Effects of Curcumin against Acetamiprid-Induced Neurotoxicity in Male Albino Rats
AbstractEnvironmental contaminants such as industrial and household chemicals, pesticides, fertilizers, heavy metals, and ionizing radiation are the...
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A Review on the Golden Plant Turmeric and Its Bioactive Compound Curcumin
Golden plant (Turmeric) has succulent, religious views with numerous pharmaceutical values. Due to its pharmaceutical values, it has been a research... -
Curcumin protects against aging-related stress and dysfunction through autophagy activation in rat brain
BackgroundCurcumin ( Curcuma longa ) is a well-known medicinal plant that induces autophagy in various model species, hel** maintain cellular...
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Effects of mesenchymal stem cells versus curcumin on sonic hedgehog signaling in experimental model of Hepatocellular Carcinoma
BackgroundSonic Hedgehog (SHH) is a fundamental signaling pathway that controls tissue reconstruction, stem cell biology, and differentiation and has...
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The Combined Impact of Curcumin: Piperine and Sorafenib on microRNAs and Different Pathways in Breast Cancer Cells
Breast cancer is the most common malignancy in the women. Chemotherapy is a crucial part of breast cancer treatment especially for advanced and...
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Curcumin displays a potent caloric restriction mimetic effect in an accelerated senescent model of rat
Curcumin, a strong natural compound with numerous health benefits, is extracted from the Curcuma longa . According to recent research findings, it...
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Evaluation of the Therapeutic Effect of Curcumin-Conjugated Zinc Oxide Nanoparticles on Reserpine-Induced Depression in Wistar Rats
Depression, a devastating brain illness, necessitates the exploration of novel antidepressant treatments. We evaluated the antidepressant effects of...
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Curcumin activates a ROS/KEAP1/NRF2/miR-34a/b/c cascade to suppress colorectal cancer metastasis
Curcumin, a natural phytochemical isolated from tumeric roots, represents a candidate for prevention and therapy of colorectal cancer/CRC. However,...
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Digestive enzyme activities, intestinal histology, and gut microbiota of Pacific white shrimp Litopenaeus vannamei fed with turmeric, curcumin, and nanomicelle curcumin
The dietary impacts of turmeric, curcumin, and nanomicelle curcumin on the digestive enzyme activities, intestinal histology, and gut microbiota of...
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Administration with curcumin alleviates spinal cord ischemia-reperfusion injury by regulating anti-oxidative stress and microglia activation-mediated neuroinflammation via Nrf2/NF-κB axis
Spinal cord ischemia-reperfusion injury (SCII) ranks as the common complication after aortic surgery, usually leading to devastating post-operative...
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The addition of curcumin to the diet of post-weaning dairy calves: effects on ruminal fermentation, immunological, and oxidative responses
Incorporating Curcumin into animal diets holds significant promise for enhancing both animal health and productivity, with demonstrated positive...
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Curcumin clarithromycin nano-form a promising agent to fight Helicobacter pylori infections
Helicobacter pylori ( H. pylori ) is the main cause of gastric diseases. However, the traditional antibiotic treatment of H. pylori is limited due to...
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Investigation of the Effect of Chestnut Honey and Curcumin Combination on Lifespan in the Experimental Heat Stress Model of Honey Bee
AbstractThe effects of global warming could be devastating to all forms of life on Earth. Premature aging and diseases related to heat stress can be...
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Utility of the second-generation curcumin analogue RL71 in canine histiocytic sarcoma
Canine histiocytic sarcoma is an aggressive cancer, with a high rate of metastasis. Thus, novel therapeutic approaches are needed. Synthetic...