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Potassium Channels Methods and Protocols
K+ channels regulate the passage of potassium ions across lipid membranes, influencing numerous biological functions, including homeostasis, sensory...
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Ion Channels in Electrical Signaling in Higher Plants
AbstractElectrical signals (ESs) appearing in plants under the action of various external factors play an important role in adaptation to changing...
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Fabrication of angstrom-scale two-dimensional channels for mass transport
Fluidic channels at atomic scales regulate cellular trafficking and molecular filtration across membranes, and thus play crucial roles in the...
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Interactomic exploration of LRRC8A in volume-regulated anion channels
Ion channels are critical in enabling ion movement into and within cells and are important targets for pharmacological interventions in different...
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Detecting organelle-specific activity of potassium channels with a DNA nanodevice
Cell surface potassium ion (K + ) channels regulate nutrient transport, cell migration and intercellular communication by controlling K + permeability...
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Fast functional map** of ligand-gated ion channels
Ligand-gated ion channels are formed by three to five subunits that control the opening of the pore in a cooperative fashion. We developed a...
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Functional Potassium Channels in Macrophages
Macrophages are the predominant component of innate immunity, which is an important protective barrier of our body. Macrophages are present in all...
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The functional effects of Piezo channels in mesenchymal stem cells
Mesenchymal stem cells (MSCs) are widely used in cell therapy, tissue engineering, and regenerative medicine because of their self-renewal,...
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The emerging role of Piezo1 channels in skeletal muscle physiology
Piezo1 channels are mechanically activated (MA) cation channels that are involved in sensing of various mechanical perturbations, such as membrane...
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Cell-Based Thallium-Influx Fluorescence Assay for Kv10.1 Channels
The development of cell-based fluorescent assays has resulted in an incredible tool for searching new ion channels’ modulators with a biophysical and...
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Voltage-Gated Calcium Channels
This book covers the tremendous progress in the current understanding of the molecular physiology of voltage-gated calcium channels. This book...
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TRP channels associated with macrophages as targets for the treatment of obese asthma
Globally, obesity and asthma pose significant health challenges, with obesity being a key factor influencing asthma. Despite this, effective...
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Hydrophobic gating in bundle-crossing ion channels: a case study of TRPV4
Transmembrane ion channels frequently regulate ion permeation by forming bundle crossing of the pore-lining helices when deactivated. The resulting...
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Cx43 hemichannels and panx1 channels contribute to ethanol-induced astrocyte dysfunction and damage
BackgroundAlcohol, a widely abused drug, significantly diminishes life quality, causing chronic diseases and psychiatric issues, with severe health,...
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The effects of doxapram and its potential interactions with K2P channels in experimental model preparations
The channels commonly responsible for maintaining cell resting membrane potentials are referred to as K2P (two-P-domain K + subunit) channels. These K + ...
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Deciphering the role of mechanosensitive channels in plant root biology: perception, signaling, and adaptive responses
Main conclusionMechanosensitive channels are integral membrane proteins that rapidly translate extrinsic or intrinsic mechanical tensions into...
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Thermal-plex: fluidic-free, rapid sequential multiplexed imaging with DNA-encoded thermal channels
Multiplexed fluorescence imaging is typically limited to three- to five-plex on standard setups. Sequential imaging methods based on iterative...
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Mechanosensitive Channels: History, Diversity, and Mechanisms
Abstract —Mechanical forces are inseparable from most cellular functions. Cell division, contraction, and adhesion generate intrinsic forces in the...
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The mechanisms of exercise improving cardiovascular function by stimulating Piezo1 and TRP ion channels: a systemic review
Mechanosensitive ion channels are widely distributed in the heart, lung, bladder and other tissues, and plays an important role in exercise-induced...
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Two types of GLR channels cooperate differently in light and dark growth of Arabidopsis seedlings
BackgroundGLutamate Receptor-like (GLR) channels are multimeric, ionotropic, ligand-gated plant transmembrane receptors. They are homologous to...
