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Cardiovascular Adverse Effects of Breast Cancer Chemotherapy
Breast cancer is the most commonly diagnosed cancer globally, with more than 2.3 million cases per year and resulting in the death of 685,000 women... -
Cardiovascular effects of the post-COVID-19 condition
Throughout the COVID-19 pandemic, the new clinical entity of the post-COVID-19 condition, defined as a multisystemic condition of persistent symptoms...
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The Effects of Sex Steroid Hormones on Cardiovascular Physiology in Females
There are fundamental sex-specific differences in cardiovascular (CV) physiology and cardiovascular disease (CVD) pathophysiology. Estrogen, a sex... -
Pathogenesis of cardiovascular diseases: effects of mitochondrial CF6 on endothelial cell function
Cardiovascular disease (CVD) stands as a predominant global cause of morbidity and mortality, necessitating effective and cost-efficient therapies...
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Diet, Epigenetics, and Cardiovascular Disease
Cardiovascular disease (CVD) poses a significant threat to human health, as it is the leading cause of death worldwide, resulting in over 18.6... -
Role of Capsaicin in Cardiovascular Diseases
Experimental evidence supports the use of dietary phytochemicals to lower the risk of cardio-related ailments. Phytochemicals found in fruits, leafy... -
Role of Polyphenols in Cardiovascular Diseases
The health advantages of polyphenols have been well documented in recent years, with particular focus on their protective effects against... -
Prediction of Adverse Effects of Drug–Drug Interactions on Cardiovascular System Based on the Analysis of Structure–Activity Relationships
AbstractCo-administration of drugs often leads to drug–drug interactions, which could be accompanied by various adverse drug reactions that pose a...
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Cardioproteomics: Insights on Cardiovascular Diseases
Cardiovascular diseases (CVDs) remain a global health challenge and are the leading cause of deaths worldwide. Proteomics has emerged as a valuable... -
Menopause and the Bridge to Cardiovascular Disease
Before menopause women are protected against cardiovascular disease morbidity and mortality, relative to age-matched men. After menopause... -
Selenium exerts protective effects on inflammatory cardiovascular damage: molecular aspects via SIRT1/p53 and Cyt-c/Cas-3 pathways
BackgroundSystemic inflammatory response could affect many systems. Cardiac dysfunction develops due to cardiovascular system damage and could be...
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Effectiveness of glucose-lowering medications on cardiovascular outcomes in patients with type 2 diabetes at moderate cardiovascular risk
Cardiovascular disease (CVD) is the leading cause of death among people with type 2 diabetes
1 –5 , most of whom are at moderate CVD risk6 , yet there is... -
Cardiovascular Consequences of Metabolic Disturbances in Women
Metabolic disorders in humans are characterized by hyperglycemia and hyperinsulinemia, insulin resistance, impaired glucose intolerance,... -
Ferroptosis in Cardiovascular Disease
Ferroptosis is a relatively newly discovered form of regulated cell death that is distinct from other forms of cell death. Ferroptosis has been... -
Hereditary hemochromatosis with homozygous C282Y HFE mutation: possible clinical model to assess effects of elevated reactive oxygen species on the development of cardiovascular disease
Hereditary hemochromatosis with the homozygous C282Y HFE mutation (HH-282H) is a genetic condition which causes iron overload (IO) and elevated...
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Molecular mechanisms of ferroptosis in cardiovascular disease
Ferroptosis is a newly recognized type of regulated cell death that is characterized by the accumulation of iron and lipid peroxides in cells....
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Ketones and the cardiovascular system
Ketone bodies, the main one being β-hydroxybutyrate, have emerged as important regulators of the cardiovascular system. In healthy individuals, as...
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Role of natural products in cardiovascular disease
As the world’s aging population increases, cardiovascular diseases (CVDs) associated with aging deserve increasing attention. CVD in association with...
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MicroRNA delivery based on nanoparticles of cardiovascular diseases
Cardiovascular disease, especially myocardial infarction, is a serious threat to human health. Many drugs currently used cannot achieve the desired...
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Current Preclinical Applications of Pharmaco-Epigenetics in Cardiovascular Diseases
Epigenetics is closely related to heart diseases. Genome-wide studies have highlighted the complexity of cardiovascular disease and involvement of...