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Anti-Acanthamoeba metallopharmaceuticals: Amoebicidal activity and synergistic effect of copper(II) coordination compound
Acanthamoeba spp. emerged as a clinically important pathogen related to amoebic keratitis. It is among the main causes of corneal transplantation and...
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Bioprospecting of Bioactive Secondary Metabolites of Endophytic Fungi of Carapichea ipecacuanha (Rubiaceae), a Neotropical Medicinal Species
The discovery of new bioactive metabolites has become a focus of study in the search for highly efficient methods for the prevention, control, and...
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Molecular mechanism of Escherichia coli H10407 induced diarrhoea and its control through immunomodulatory action of bioactives from Simarouba amara (Aubl.)
Enterotoxigenic Escherichia coli (ETEC) infection is a major cause of death in children under the age of five in develo** countries. ETEC...
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Review of Piper species growing in the Brazilian State of Paraná with emphasize on the vegetative anatomy and biological activities
The State of Parana has a diversity of plants that are used in the traditional medicine and among them are some of the representatives of the...
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Ethnomedicine and Role of Plant Metabolites
Plants have been used for the treatment of various human ailments since ancient times. Bioactive compounds of plant origin are of great interest in...
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Phytochemical and Biological Properties of Lippia gracilis
Lippia gracilis Schauer is popularly known as “alecrim-da-chapada” and “candeia-de-queimar.” It is a native plant in the semiarid region of Northeast...
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Master Molecules of Spices
Spices are natural products of plant origin, used primarily for flavoring, for seasoning, or for adding pungency and color or all of them to foods...
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Spices: Definition, Classification, History, and Role in Indian Life
Spices are natural products of plant origin, used primarily for flavoring and seasoning or for adding pungency and color to foods and beverages. The...
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Egg Derived Ovotransferrins and Lactoferrins
Proteins and minerals are integral parts of the biological system that harmonize and sustain life. Minerals such as iron binds with protein and is...
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Oxidative Stress and Antioxidant Defense Mechanism in the Human Enteric Protozoan Parasite Entamoeba histolytica
Entamoeba histolytica is an intestinal protozoan parasite that causes amebic dysentery and liver abscess in millions of inhabitants of endemic areas....
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Water-Soluble Ruthenium Complexes Bearing Activity Against Protozoan Parasites
Parasitic illnesses are major causes of human disease and misery worldwide. Among them, both amebiasis and Chagas disease, caused by the protozoan...
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Study of Drug-Nucleic Acid Interactions: 9-amino- [N-2-(4-morpholinyl)ethyl]acridine-4-carboxamide
9-amino-[N-2-(4-morpholinyl)ethyl]acridine-4-carboxamide (9AMC) elicits its antitumour activity through intercalative binding with the genetic...
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Introduction to the Different Classes of Natural Products
Plants produce an enormous variety of natural products with highly diverse structures. These products are commonly termed “secondary metabolites” in...
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In vitro and in vivo activity of extracts from the soft coral Lobophytum pauciflorum on trophozoites of Entamoeba histolytica
Methanolic extracts from the marine coral Lobophytum pauciflorum exhibited an in vitro amebicidal activity against trophozoites of Entamoeba...
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Protein N-terminal methionine excision
N-terminal methionine excision (NME) is the major proteolytic pathway responsible for the diversity of N-terminal amino acids in proteins. Dedicated...
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Health Effects of Acanthamoeba spp. and Its Potential for Waterborne Transmission
Risk from Acanthamoeba keratitis is complex, depending upon the virulence of the particular strain, exposure, trauma, or other stress to the eye, and...
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Carbon and Nitrogen Source Nutrition of Fumagillin Biosynthesis by Aspergillus fumigatus
The carbon and nitrogen source requirements of Aspergillus fumigatus NRRL 2436 for growth and production of the angiogenesis inhibitor fumagillin...
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Toward the chemical ecology of medicinal plant use in chimpanzees: The case ofVernonia amygdalina, a plant used by wild chimpanzees possibly for parasite-related diseases
The bitter and related constituents have been isolated from Vernonia amygdalina (Compositae), a plant ingested by wild chimpanzees possibly suffering...
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Detrimental effects ofCinchona leaf alkaloids on larvae of the polyphagous insectSpodoptera exigua
Young Cinchona ledgeriana plants contain two types of alkaloid: indole alkaloids in the leaves and quinoline alkaloids in the root. From Cinchona ...