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Genome-wide perturbations of Alu expression and Alu-associated post-transcriptional regulations distinguish oligodendroglioma from other gliomas
Alu is a primate-specific repeat element in the human genome and has been increasingly appreciated as a regulatory element in many biological...
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Quantitative PCR of Alu Repeats Using PowerUp™ SYBR® Green Master Mix
Quantitative PCR is one of the fundamental steps performed when processing routine casework in a forensic laboratory. Quantitative PCR of Alu repeats...
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BARI Alu-86—An Early-Bulker, High Yielding and Quality Potato (Solanum tuberosum L.) Cultivar Suitable for Diverse Environments
BARI Alu-86 (12.13) is a potato variety with medium maturity (92.2 days) and rapid tuber bulking which makes it fit for early and full-season...
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cGAS inhibition alleviates Alu RNA-induced immune responses and cytotoxicity in retinal pigmented epithelium
BackgroundThe degeneration of retinal pigmented epithelium (RPE) cells results in severe diseases, such as age-related macular degeneration (AMD)...
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meta-Topolin-induced in vitro propagation, field evaluation, flow cytometry and molecular marker-based genetic stability assessment of potato cv. Badami alu
Potato ( Solanum tuberosum L.), belonging to Solanaceae family, globally ranks as the fourth-largest food (vegetable) crop. In order to sustain the...
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Structural analysis of the SRP Alu domain from Plasmodium falciparum reveals a non-canonical open conformation
The eukaryotic signal recognition particle (SRP) contains an Alu domain, which docks into the factor binding site of translating ribosomes and...
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The L1-dependant and Pol III transcribed Alu retrotransposon, from its discovery to innate immunity
The 300 bp dimeric repeats digestible by Alu I were discovered in 1979. Since then, Alu were involved in the most fundamental epigenetic mechanisms,...
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Homotypic clustering of L1 and B1/Alu repeats compartmentalizes the 3D genome
Organization of the genome into euchromatin and heterochromatin appears to be evolutionarily conserved and relatively stable during lineage...
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Molecular determination of progesterone receptor’s PROGINS allele (Alu insertion) and its association with the predisposition and susceptibility to polycystic ovary syndrome (PCOS)
Polycystic ovary syndrome, previously known as Stein–Leventhal syndrome, is associated with altered reproductive endocrinology, predisposing a young...
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A comprehensive analysis of chimpanzee (Pan Troglodytes)-specific AluYb8 element
BackgroundAlu elements are most abundant retrotransposons with > 1.2 million copies in the primate genome. Alu Yb8 subfamily was diverged from Alu Y...
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Evaluation of Late Blight (Phytophthora infestans L.) Tolerant Potato Varieties for Northern Bangladesh
The precarious potato disease known as late blight (LB), which is brought on by Phytophthora infestans , quickly decimates crops and economically...
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LDLR gene rearrangements in Czech FH patients likely arise from one mutational event
BackgroundLarge deletions and duplications within the low-density lipoprotein receptor ( LDLR) gene make up approximately 10% of LDLR pathogenic...
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What factors are influencing peri-urban forest carbon storage in different land use types based on permanent plots from 2009–2018
Urban forests are crucial in reducing atmospheric carbon dioxide (CO 2 ) concentrations. Forest structure and composition in particular are important...
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Alu retrotransposons modulate Nanog expression through dynamic changes in regional chromatin conformation via aryl hydrocarbon receptor
Transcriptional repression of Nanog is an important hallmark of stem cell differentiation. Chromatin modifications have been linked to the epigenetic...
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Zero Tillage Potato Cultivation Following Rice in the Coastal Ganges Delta
Zero tillage potato is attracting increasing attention for crop** system intensification in the saline coastal zone of the Ganges Delta. With the...
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capTEs enables locus-specific dissection of transcriptional outputs from reference and nonreference transposable elements
Transposable elements (TEs) serve as both insertional mutagens and regulatory elements in cells, and their aberrant activity is increasingly being...
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The mutational dynamics of short tandem repeats in large, multigenerational families
BackgroundShort tandem repeats (STRs) compose approximately 3% of the genome, and mutations at STR loci have been linked to dozens of human diseases...
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Adenosine to inosine RNA editing in animal cells
Major advances in the understanding of adenosine deaminases acting on RNA (ADARs) have come from the generation of ADAR mutant animals. In mice,...
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Bi-directional Transcription, Double-Stranded RNA and the Implications on Genome Evolution
Double-stranded RNA (dsRNA) within cells indicates viral infection and triggers a robust innate immune response. Counterintuitively, cells also...
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Deciphering the role of extrachromosomal circular DNA in adipose stem cells from old and young donors
BackgroundThe functional impairment of adipose stem cells (ASCs) during aging limits their clinical transformation. Studies have shown that...
