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Clinical epidemiology of adenovirus pneumonia among Chinese hospitalized children
Adenovirus pneumonia is a prevalent form of community-acquired pneumonia among children. Research on the epidemiology and economic burden of this...
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In Silico Intensive Analysis for the E4 Gene Evolution of Human Adenovirus Species D
Adenovirus (Ad) is a ubiquitous pathogen capable of infecting a wide range of animals and humans. Human Adenovirus (HAdV) can cause severe infection,...
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Caveats of chimpanzee ChAdOx1 adenovirus-vectored vaccines to boost anti-SARS-CoV-2 protective immunity in mice
AbstractSeveral COVID-19 vaccines use adenovirus vectors to deliver the SARS-CoV-2 spike (S) protein. Immunization with these vaccines promotes...
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Genetic diversity of adenovirus in neotropical bats from Brazil
Bats can harbor a diversity of viruses, such as adenovirus. Ten different species of bat adenoviruses ( BtAdV A to J ) have been...
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Global investigation of the presence of adenovirus in different types of water resources: a systematic review
Waterborne viruses such as adenoviruses cause major health problems in the world. Human adenoviruses are the second leading cause of childhood...
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The Diagnostic Potential of Monoclonal Antibodies to Adenovirus
The diagnostic potential of the 4B7 and 6B12 monoclonal antibodies (MAbs) against human adenovirus hexon protein has been studied in various...
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Identification of a novel adenovirus in liver tissue sample of the Great Himalayan leaf-nosed bat (Hipposideros armiger)
Bats are important reservoirs for many zoonotic viruses. To explore and monitor potential novel viruses carried by bats, 21 liver samples of bats ( Hip...
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Genomic Evolution and Recombination Dynamics of Human Adenovirus D Species: Insights from Comprehensive Bioinformatic Analysis
Human adenoviruses (HAdVs) can infect various epithelial mucosal cells, ultimately causing different symptoms in infected organ systems. With more...
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Circulation of adenovirus and other viruses in urban drainage channels: an environmental surveillance in Belém, Amazon region, Brazil
Urban channels in amazon cities are very polluted, with garbage and sewage disposal in these aquatic environments, favoring the high dissemination of...
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Development of a perfusion process for serum-free adenovirus vector herpes zoster vaccine production
Herpes zoster is caused by reactivation of the varicella zoster virus (VZV). Researching and develo** a herpes zoster vaccine will help to decrease...
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Canine distemper virus and canine adenovirus type 1 co-infection in a free-living hoary fox (Lycalopex vetulus) from Brazil
The present case is the first description of a co-infection with canine distemper virus (CDV) and canine adenovirus type 1 (CAdV-1) in a free-living...
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Identification of novel B cell epitopes in Fiber-2 protein of duck adenovirus 3 and their application
Duck adenovirus 3 (DAdV-3), a newly emerged duck adenovirus, has resulted in significant economic losses to the duck industry across China since...
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Optimization of an adenovirus-vectored zoster vaccine production process with chemically defined medium and a perfusion system
ObjectivesCells grown in chemically defined medium are sensitive to shear force, potentially resulting in decreased cell growth. We optimized the...
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Preparation and identification of a single domain antibody specific for adenovirus vectors and its application to the immunoaffinity purification of adenoviruses
Adenovirus belongs to the family of Adenoviridae. As a vaccine carrier, it has high safety and stimulates the body to produce cellular immunity and...
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Long-term antigen-specific immune response by an oncolytic adenovirus encoding SP-SA-E7-4-1BBL in HPV-16 cancer model
BackgroundTo describe an oncolytic adenovirus (OAd) encoding SP-SA-E7-4-1BBL that is capable of inducing tumor regression in therapeutic assays....
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Inactivation mechanisms of human adenovirus by e-beam irradiation in water environments
AbstractThis study aims to study the kinetics and mechanisms of human adenovirus inactivation by electron beam. Human adenovirus type 5 (HAdV-5) was...
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Antiviral activity of canine interferon lambda 3 expressed using a recombinant adenovirus against canine coronavirus, canine parvovirus, and canine distemper virus
Canine coronavirus (CCoV), canine parvovirus (CPV), and canine distemper virus (CDV) are highly contagious canine pathogens; dogs with these diseases...
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Turkey adenovirus 3: ORF1 gene sequence comparison between vaccine-like and field strains
Haemorrhagic enteritis is an economically significant disease reported in the majority of the countries where turkeys are raised intensively; it is...
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Spike-based adenovirus vectored COVID-19 vaccine does not aggravate heart damage after ischemic injury in mice
An unprecedented number of COVID-19 vaccination campaign are under way worldwide. The spike protein of SARS-CoV-2, which majorly binds to the host...