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The wound microbiota: microbial mechanisms of impaired wound healing and infection
The skin barrier protects the human body from invasion by exogenous and pathogenic microorganisms. A breach in this barrier exposes the underlying...
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Cellular and molecular mechanisms of skin wound healing
Wound healing is a complex process that involves the coordinated actions of many different tissues and cell lineages. It requires tight orchestration...
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Peptides and Wound Healing: From Monomer to Combination
Peptides are a kind of compounds formed by α-amino acids linked together by peptide bonds, which are also intermediate products of protein...
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Macrophages regulate healing-associated fibroblasts in diabetic wound
BackgroundRecovery from a foot ulcer is compromised in a diabetic status, due to the impaired tissue microenvironment that consists of altered...
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Fabricating Composite Cell Sheets for Wound Healing: Cell Sheets Based on the Communication Between BMSCs and HFSCs Facilitate Full-Thickness Cutaneous Wound Healing
Background:Insufficient angiogenesis and the lack of skin appendages are critical challenges in cutaneous wound healing. Stem cell-fabricated cell...
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Reproducible strategy for excisional skin-wound-healing studies in mice
Wound healing is a complex physiological process involving various cell types and signaling pathways. The capability to observe the dynamics of wound...
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ER-mitochondria association negatively affects wound healing by regulating NLRP3 activation
Methicillin-resistant Staphylococcus aureus (MRSA) is the most common causative agent of acute bacterial skin and skin-structure infections (ABSSSI),...
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The effects of Quercetin on wound healing in the human umbilical vein endothelial cells
An injury that affects the integrity of the skin, either inside or externally, is called a wound. Damaged tissue is repaired by a set of cellular and...
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Cydonia oblonga Mill.: Wound Healing Properties
Traditional and indigenous medicines make significant use of natural raw materials and derivatives of natural products. Cydonia oblonga Mill,...
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Exosomes Derived from Mouse Breast Carcinoma Cells Facilitate Diabetic Wound Healing
BACKGROUND:Exosomes derived from breast cancer have been reported to play a role in promoting cell proliferation, migration, and angiogenesis, which...
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Gravitational effects on fibroblasts’ function in relation to wound healing
The spaceflight environment imposes risks for maintaining a healthy skin function as the observed delayed wound healing can contribute to increased...
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Immediate but Temporal Response: The Role of Distal Epithelial Cells in Wound Healing
Efficient oral mucosal wound healing requires coordinated responses from epithelial progenitor cells, yet their spatiotemporal recruitment and...
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Redox signaling in impaired cascades of wound healing: promising approach
In the aging communities, wound healing management is a quite remarkable problem especially in elderly individuals. The optimal level of healing of...
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Accelerated wound healing with resveratrol‐loaded decellularized pericardium in mice model
One of the key objectives of regenerative medicine is the design of skin tissue engineering scaffolds to promote wound healing. These scaffolds...
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Advancements in wound healing: integrating biomolecules, drug delivery carriers, and targeted therapeutics for enhanced tissue repair
Wound healing, a critical biological process vital for tissue restoration, has spurred a global market exceeding $15 billion for wound care products...
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Genome-wide screening of m6A profiling of cutaneous wound healing in diabetic mice
ObjectiveImpaired wound healing in diabetes mellitus (DM) is a major health burden on patients, their families, and society. The present study aimed...
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Superior In Vivo Wound-Healing Activity of Biosynthesized Silver Nanoparticles with Nepeta cataria (Catnip) on Excision Wound Model in Rat
Silver nanoparticles were biosynthesized with Nepeta cataria plant extract. It was determined that the synthesized Nc-AgNPs gave a strong absorbance...
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Human Epithelial Protein SLURP-2 as a Prototype of Drugs for Wound Healing
AbstractObjective: Wound healing is a complex process based on the regulation of proliferation and migration of epithelial cells. Chronic wounds are...
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The Angiogenic Repertoire of Stem Cell Extracellular Vesicles: Demystifying the Molecular Underpinnings for Wound Healing Applications
Stem cells-derived extracellular vesicles (SC-EVs) have emerged as promising therapeutic agents for wound repair, recapitulating the biological...
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Mesenchymal Stromal Cells for Wound Healing Therapy: From Expectations to Reality
This chapter addresses the therapeutic potential of mesenchymal stromal/stem cells (MSCs), focusing on those derived from bone marrow and adipose...