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Withanolides production by the endophytic fungus Penicillium oxalicum associated with Withania somnifera (L.) Dunal
Withanolides are steroidal lactones with diverse bioactive potential and their production from plant sources varies with genotype, age, culture...
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Melatonin Confers NaCl Tolerance in Withania coagulans L. by Maintaining Na+/K+ Homeostasis, Strengthening the Antioxidant Defense System and Modulating Withanolides Synthesis-Related Genes
AbstractAs a multifunctional signaling molecule, melatonin (ML) is widely considered to induce the defense mechanism and increase the accumulation of...
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A novel approach for direct shoot regeneration, anatomical characterization, and withanolides content in micropropagated plants of Withania somnifera (L.) Dunal—an important medicinal plant
Withania somnifera (Ashwagandha) is a valuable therapeutic plant used in many Ayurvedic drugs marketed for health restoration. However, its...
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Short term UV-B radiation mediated modulation of physiological traits and withanolides production in Withania coagulans (L.) Dunal under in-vitro condition
Accumulation of secondary metabolites is a key process in the growth and development of plants under different biotic/abiotic constraints. Many...
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Isolation and characterization of endophytic fungi having plant growth promotion traits that biosynthesizes bacosides and withanolides under in vitro conditions
Endophytes are regarded with immense potentials in terms of plant growth promoting (PGP) elicitors and mimicking secondary metabolites of medicinal...
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Involvement of MYB family transcription factors, WsMYBL1 and WsMYBL2, in withanolide biosynthesis in Withania somnifera, a medicinal plant
Withania somnifera , a valuable medicinal plant, synthesizes low molecular weight secondary metabolites known as withanolides with beneficial...
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Impact of green synthesized WcAgNPs on in-vitro plant regeneration and withanolides production by inducing key biosynthetic genes in Withania coagulans
Key messageWithania coagulans (L.) Dunal bio-synthesized silver nanoparticles (WcAgNPs) worked as an abiotic elicitor or auto-catalyst that enhanced...
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Phytochemicals of Withania somnifera and Their Perspective on Plant Defense Against Stress
Plants produce a variety of phytochemicals in response to the different biotic or abiotic stress conditions. These metabolites not provide protection...
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Iron Oxide Nanoparticle-Induced Changes in the Growth, Oxidative Responses, and Antioxidant Capacity of Physalis alkekengi Seedlings
AbstractIn this study, the impact of Fe 3 O 4 nanoparticles (NPs) at different concentrations was studied on physiology, antioxidant enzymes, cell...
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Effects of nodding broomrape parasitism on growth, physio-biochemical changes and yield loss of Withania somnifera (Linn.) Dunal plant
Ashwagandha ( Withania somnifera Dunal. Linn.) also known as Indian ginseng is the most widely used herb to boost the immune system. The main economic...
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Critical factors influencing in vitro propagation and modulation of important secondary metabolites in Withania somnifera (L.) dunal
Withania somnifera (L.) Dunal is a valuable medicinal plant in the Solanaceae family. It is commonly known as Ashwagandha and is widely distributed...
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Jasmonate responsive transcription factor WsMYC2 regulates the biosynthesis of triterpenoid withanolides and phytosterol via key pathway genes in Withania somnifera (L.) Dunal
Key messageFunctional characterization of Ws MYC2 via artificial microRNA mediated silencing and transient over-expression displayed significant...
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Metabolites and Phytochemicals in Medicinal Plants Used in the Management and Treatment of Neurological Diseases
In medicine, neurological disorders can be well defined as disorders which affect the brain and nerves found all through the body of humans as well...
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Searching for bioactive compounds from Solanaceae: lethal and sublethal toxicity to Spodoptera frugiperda and untargeted metabolomics approaches
The fall armyworm, Spodoptera frugiperda (J.E. Smith) (Lepidoptera: Noctuidae), is a major pest of maize crops and others row crops on the American...
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Elicitation Improves the Production of Bioactive Compounds and Antioxidant Activity in Cell Suspension Culture of Withania coagulans (Stocks) Dunal
AbstractAbiotic and biotic elicitors may induce higher synthesis of bioactive compounds in medicinal plants. In the present study, the impact of...
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Structure-based drug design-guided identification of estrogen receptor binders
Cancer is one of the life-threatening diseases and the second leading cause of death in the world. The estrogen receptor can be considered as one of...
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Virus-Induced Gene Silencing for Functional Genomics in Withania somnifera, an Important Indian Medicinal Plant
Virus-induced gene silencing (VIGS) has emerged as a fast and efficient reverse and forward genetics tool to study gene function in model plants as...
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Plant-Derived Drugs for Alzheimer’s Disease and Other Neurological Disorders
Alzheimer’s disease (AD) is a progressive, debilitating neurological disorder associated with chronic damage to neuronal cells that result in the...
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Salt induced modulations in morphological, physiological, and metabolic attributes in in-vitro grown shoots of Withania somnifera (L.) Dunal
Due to the increasing dependency of the global population on herbal-based medicines, enhanced production of secondary metabolites has become utmost...
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Tissue Culture Techniques to Conserve Endangered Medicinal Plants with Antimicrobial and Antiviral Activities
Approximately four-fifths of the world’s population has long relied on medicinal plants in the form of traditional formulations for their primary...