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Impact of Ebola virus nucleoprotein on VP40 virus-like particle production: a computational approach
Ebola virus (EBOV) matrix protein VP40 can assemble and bud as virus-like particles (VLPs) when expressed alone in mammalian cells. Nucleoprotein...
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Plant Virus-Like Particles for RNA Delivery
Plant viruses such as brome mosaic virus and cowpea chlorotic mottle virus are effectively purified through PEG precipitation and sucrose cushion...
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Plant Molecular Farming: Production of Virus-like Particles in Plants
Plant molecular farmingPlant molecular farming, or biopharmingBiopharming, is the production of heterologous proteins in plants or plant cells. This...
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Nanoparticle and virus-like particle vaccine approaches against SARS-CoV-2
The global spread of coronavirus disease 2019 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has provoked an urgent...
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Bacteriophage Virus-Like Particles: Platforms for Vaccine Design
Virus-like particles (VLPs) derived from bacteriophages have many applications in biomedical sciences, especially in the development of candidate...
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Expression of virus-like particles (VLPs) of foot-and-mouth disease virus (FMDV) using Saccharomyces cerevisiae
AbstractWe engineered Saccharomyces cerevisiae to express structural proteins of foot-and-mouth disease virus (FMDV) and produce virus-like...
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Bioengineering and Bioprocessing of Virus-Like Particle Vaccines in Escherichia coli
Virus-like particles (VLPs) are macromolecular assemblies of recombinant viral structural proteins. Self-assembling with high precision, the...
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Isolation and infection cycle of a polinton-like virus virophage in an abundant marine alga
Virophages are small double stranded DNA (dsDNA) viruses that can only replicate in a host by co-infecting with another virus. Marine algae are...
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The artificial production of viral-like particles in Nicotiana benthamiana suggests the pro-assembly role of the Cannabis cryptic virus RdRP
The partitivirids feature an icosahedral protein coating accommodating both their dsRNA genome and RNA-dependent RNA polymerase (RdRP). This...
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Design and characterization of chimeric Rabies-SARS-CoV-2 virus-like particles for vaccine purposes
AbstractDue to the high number of doses required to achieve adequate coverage in the context of COVID-19 pandemics, there is a great need for novel...
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Low-temperature culture enhances production of flavivirus virus-like particles in mammalian cells
AbstractFlavivirus virus-like particles (VLPs) exhibit a striking structural resemblance to viral particles, making them highly adaptable for various...
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On-column refolding and off-column assembly of parvovirus B19 virus-like particles from bacteria-expressed protein
AbstractVirus-like particles (VLPs) are nanometric structures composed of structural components of virions, kee** most of the cellular recognition...
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Engineered virus-like particles for transient delivery of prime editor ribonucleoprotein complexes in vivo
Prime editing enables precise installation of genomic substitutions, insertions and deletions in living systems. Efficient in vitro and in vivo...
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CryoEM and stability analysis of virus-like particles of potyvirus and ipomovirus infecting a common host
Sweet potato feathery mottle virus (SPFMV) and Sweet potato mild mottle virus (SPMMV) are members of the genera Potyvirus and Ipomovirus , family Potyviridae...
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Recombinantly expressed virus-like particles (VLPs) of canine circovirus for development of an indirect ELISA
Canine circovirus (CanineCV) is an emerging pathogen in domestic dogs, detected in multiple countries in association with varying clinical and...
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The Biotechnological Potential of Methylotrophic Yeast Komagataella phaffii (Pichia pastoris) for Assembly of Bacteriophage MS2 Virus-Like Particles
Successful assembly of bacteriophage MS2 virus-like particles (VLPs) from a secreted recombinant capsid protein in the culture medium of the Komagatael...
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Drosophila X virus-like particles as efficient dsRNA carriers for improved RNAi against the invasive species, Drosophila suzukii
RNA interference (RNAi) has been exploited as a promising strategy for pest control and also has great potential against the spotted wing drosophila...
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Antigenicity and immunogenicity of chikungunya virus-like particles from mosquito cells
AbstractThe spread of chikungunya virus (CHIKV) is reaching pandemic levels, and vaccines and antivirals to control CHIKV infection have yet to be...
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Develo** a vaccine against velogenic sub-genotype seven of Newcastle disease virus based on virus-like particles
In the present study, for the first time, we released and assembled the particles of three major structural proteins of velogenic NDV (M, HN, and F...
