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Regulation of urea cycle by reversible high-stoichiometry lysine succinylation
The post-translational modification lysine succinylation is implicated in the regulation of various metabolic pathways. However, its biological...
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Amino acids downregulate SIRT4 to detoxify ammonia through the urea cycle
Ammonia production via glutamate dehydrogenase is inhibited by SIRT4, a sirtuin that displays both amidase and non-amidase activities. The processes...
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TET2 is required to suppress mTORC1 signaling through urea cycle with therapeutic potential
Tumor development, involving both cell growth (mass accumulation) and cell proliferation, is a complex process governed by the interplay of multiple...
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Evaluation of Urea Cycle Activity by Metabolic Flux Analysis Using Mass Spectrometry
Hepatocytes play an important role in maintaining homeostasis in living organisms by carrying out various metabolic functions. The urea cycle, one of... -
The mitochondrial protein Opa1 promotes adipocyte browning that is dependent on urea cycle metabolites
White to brown/beige adipocytes conversion is a possible therapeutic strategy to tackle the current obesity epidemics. While mitochondria are key for...
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Assessing Protein Interactions for Clustering of Mitochondrial Urea Cycle Enzymes
Enzyme clusteringEnzyme clustering is a phenomenon that involves partitioning of proteins that function together in a common subcellular or... -
Early onset of urea synthesis and ammonia detoxification pathways in three terrestrially develo** frogs
Frogs evolved terrestrial development multiple times, necessitating mechanisms to avoid ammonia toxicity at early stages. Urea synthesis from ammonia...
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Guanyl urea phosphate-based adhesive for fire-retardant particleboard
Particle board is widely used for panelling, partitioning and ceiling in buildings. A novel type of flame-retardant particle board was prepared based...
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Estimation of urea reaction rate constants in paddy fields
Paddy accounts for a significant share of fertilizer consumption among agricultural crops. Urea is the widely used nitrogenous fertilizer for paddy....
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Circadian rhythm of salivary and serum urea concentration in alpacas and sheep receiving diets with different levels of protein
All vertebrates possess a daily rhythm, encompassing a comprehensive set of physiological, cognitive, and behavioral patterns that manifest...
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DMPP-urea restricts nitrification in the first month without improving agronomic N use efficiency
Enhanced efficiency N fertilisers (EENF) including DMPP-urea (Entec®) can lower nitrous oxide emissions compared to urea, but evidence for higher...
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Optimization of Urea Fertilization with Various Doses and Applications on the Yield and Quality of the Hazelnut
Nitrogen (N) fertilization is one of the necessary elements in the production of hazelnuts. Therefore, the excessive introduction of nitrogen into...
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Site-specific recommendations of cattle manure nitrogen and urea for silage maize
A novel decision support system (DSS) was developed to define site-specific cattle manure rates with the aim of increasing the stable pool of soil...
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Urea glyoxal and urea melamine glyoxal wood adhesives hardened with acid ionic liquid for particleboard pressing
In wood based panel industry, formaldehyde based adhesives are widely employed for bonding, and formaldehyde released from panels negatively affects...
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Effects of C and N application on Azotobacter and nitrogen cycle in farmland soils of central Guizhou, China
Carbon sources and nitrogen sources are two important groups of substances in analyses of the effects of exogenous additives on soil microorganisms....
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Cell Cycle Map** Using Multiplexed Immunofluorescence
The development of technologies that allow measurement of the cell cycle at the single-cellSingle-cell level has revealed novel insights into the... -
Effects of arginine replacement with L-citrulline on the arginine/nitric oxide metabolism in chickens: An animal model without urea cycle
BackgroundThis study examined the efficacy of L- citrulline supplementation on the arginine/nitric oxide metabolism, and intestinal functions of...
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Design, Synthesis and Herbicidal Evaluation of Novel Urea Derivatives with Inhibition Activity to Root Growth
In our previous work, compound Y9k, 1-phenethyl-3- (3-(trifluoromethyl) phenyl) urea, displayed significant inhibition activity on root growth of Arabidopsis...
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Poultry litter increased irrigated cotton N uptake with limited improvement on 15N-labelled urea recovery over one season
Limited field research has investigated the impact of poultry litter (PL) on urea-nitrogen (N) recovery in irrigated crop** systems. This study...