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  1. Regulation of urea cycle by reversible high-stoichiometry lysine succinylation

    The post-translational modification lysine succinylation is implicated in the regulation of various metabolic pathways. However, its biological...

    Ran Zhang, **gqi Fang, ... Eric Verdin in Nature Metabolism
    Article 06 March 2024
  2. Amino acids downregulate SIRT4 to detoxify ammonia through the urea cycle

    Ammonia production via glutamate dehydrogenase is inhibited by SIRT4, a sirtuin that displays both amidase and non-amidase activities. The processes...

    Song-Hua Hu, Yu-Yang Feng, ... Shi-Min Zhao in Nature Metabolism
    Article 20 April 2023
  3. TET2 is required to suppress mTORC1 signaling through urea cycle with therapeutic potential

    Tumor development, involving both cell growth (mass accumulation) and cell proliferation, is a complex process governed by the interplay of multiple...

    **g He, Mingen Lin, ... Lei Lv in Cell Discovery
    Article Open access 08 August 2023
  4. Evaluation of Urea Cycle Activity by Metabolic Flux Analysis Using Mass Spectrometry

    Hepatocytes play an important role in maintaining homeostasis in living organisms by carrying out various metabolic functions. The urea cycle, one of...
    Yasuharu Ueno, Takuji Maeda, ... Hideki Taniguchi in Hepatocytes
    Protocol 2022
  5. The mitochondrial protein Opa1 promotes adipocyte browning that is dependent on urea cycle metabolites

    White to brown/beige adipocytes conversion is a possible therapeutic strategy to tackle the current obesity epidemics. While mitochondria are key for...

    Camilla Bean, Matteo Audano, ... Luca Scorrano in Nature Metabolism
    Article 06 December 2021
  6. Assessing Protein Interactions for Clustering of Mitochondrial Urea Cycle Enzymes

    Enzyme clusteringEnzyme clustering is a phenomenon that involves partitioning of proteins that function together in a common subcellular or...
    Ljubica Caldovic, Shivaprasad Bhuvanendran, Jyoti Jaiswal in Multienzymatic Assemblies
    Protocol 2022
  7. Early onset of urea synthesis and ammonia detoxification pathways in three terrestrially develo** frogs

    Frogs evolved terrestrial development multiple times, necessitating mechanisms to avoid ammonia toxicity at early stages. Urea synthesis from ammonia...

    Javier Méndez-Narváez, Karen M. Warkentin in Journal of Comparative Physiology B
    Article 28 August 2023
  8. Guanyl urea phosphate-based adhesive for fire-retardant particleboard

    Particle board is widely used for panelling, partitioning and ceiling in buildings. A novel type of flame-retardant particle board was prepared based...

    Article 11 January 2024
  9. Estimation of urea reaction rate constants in paddy fields

    Paddy accounts for a significant share of fertilizer consumption among agricultural crops. Urea is the widely used nitrogenous fertilizer for paddy....

    S. Vanitha, V. Ravikumar, T. Sherene Jenita Rajammal in Paddy and Water Environment
    Article 03 June 2023
  10. Circadian rhythm of salivary and serum urea concentration in alpacas and sheep receiving diets with different levels of protein

    All vertebrates possess a daily rhythm, encompassing a comprehensive set of physiological, cognitive, and behavioral patterns that manifest...

    Juan Olazabal-Loaiza, Luis A. Gomez-Puerta, ... Carlos A. Gómez-Bravo in Veterinary Research Communications
    Article 03 May 2024
  11. DMPP-urea restricts nitrification in the first month without improving agronomic N use efficiency

    Enhanced efficiency N fertilisers (EENF) including DMPP-urea (Entec®) can lower nitrous oxide emissions compared to urea, but evidence for higher...

    Terry J. Rose, Lee J. Kearney, ... Michael T. Rose in Nutrient Cycling in Agroecosystems
    Article 07 April 2023
  12. Optimization of Urea Fertilization with Various Doses and Applications on the Yield and Quality of the Hazelnut

    Nitrogen (N) fertilization is one of the necessary elements in the production of hazelnuts. Therefore, the excessive introduction of nitrogen into...

    Faruk Özkutlu, Metin Turan, ... Ayhan Kocaman in Applied Fruit Science
    Article 26 April 2024
  13. Site-specific recommendations of cattle manure nitrogen and urea for silage maize

    A novel decision support system (DSS) was developed to define site-specific cattle manure rates with the aim of increasing the stable pool of soil...

    Martina Corti, Daniele Cavalli, ... Giovanni Cabassi in Nutrient Cycling in Agroecosystems
    Article 28 July 2023
  14. Urea glyoxal and urea melamine glyoxal wood adhesives hardened with acid ionic liquid for particleboard pressing

    In wood based panel industry, formaldehyde based adhesives are widely employed for bonding, and formaldehyde released from panels negatively affects...

    Ümran Burcu Alkan, Nilgün Kızılcan, Başak Bengü in European Journal of Wood and Wood Products
    Article 02 April 2022
  15. Effects of C and N application on Azotobacter and nitrogen cycle in farmland soils of central Guizhou, China

    Carbon sources and nitrogen sources are two important groups of substances in analyses of the effects of exogenous additives on soil microorganisms....

    Zhiwei Qiao, Chao Liu, ... Shihua Qin in Chemical and Biological Technologies in Agriculture
    Article Open access 04 December 2023
  16. Cell Cycle Map** Using Multiplexed Immunofluorescence

    The development of technologies that allow measurement of the cell cycle at the single-cellSingle-cell level has revealed novel insights into the...
    Katarzyna M. Kedziora, Wayne Stallaert in Cell Cycle Control
    Protocol 2024
  17. Effects of arginine replacement with L-citrulline on the arginine/nitric oxide metabolism in chickens: An animal model without urea cycle

    Background

    This study examined the efficacy of L- citrulline supplementation on the arginine/nitric oxide metabolism, and intestinal functions of...

    Victoria Anthony Uyanga, Li**g Sun, ... Hai Lin in Journal of Animal Science and Biotechnology
    Article Open access 01 February 2023
  18. Design, Synthesis and Herbicidal Evaluation of Novel Urea Derivatives with Inhibition Activity to Root Growth

    In our previous work, compound Y9k, 1-phenethyl-3- (3-(trifluoromethyl) phenyl) urea, displayed significant inhibition activity on root growth of Arabidopsis...

    Lin Du, Zhikun Yang, ... Liusheng Duan in Journal of Plant Growth Regulation
    Article 27 November 2022
  19. Poultry litter increased irrigated cotton N uptake with limited improvement on 15N-labelled urea recovery over one season

    Limited field research has investigated the impact of poultry litter (PL) on urea-nitrogen (N) recovery in irrigated crop** systems. This study...

    Jackie R. Webb, Rakesh Awale, Wendy C. Quayle in Nutrient Cycling in Agroecosystems
    Article 02 December 2022
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