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Structural insights into the mechanism of protein transport by the Type 9 Secretion System translocon
Secretion systems are protein export machines that enable bacteria to exploit their environment through the release of protein effectors. The Type 9...
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Auxin Transport and Recycling of PIN Proteins in Plants
Polar transport of the phytohormone auxin is mediated by plasma-membrane and endosome localized carrier proteins. PIN proteins are the best...
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Amino acid (acyl carrier protein) ligase-associated biosynthetic gene clusters reveal unexplored biosynthetic potential
This study aimed to evaluate the postulated cellular function of a novel family of amino acid (acyl carrier protein) ligases (AALs) in natural...
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Microbial membrane transport proteins and their biotechnological applications
Because of the hydrophobic nature of the membrane lipid bilayer, the majority of the hydrophilic solutes require special transportation mechanisms...
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SCP2 mediates the transport of lipid hydroperoxides to mitochondria in chondrocyte ferroptosis
Sterol carrier protein 2 (SCP2) is highly expressed in human osteoarthritis (OA) cartilage, accompanied by ferroptosis hallmarks, especially the...
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Heterologous protein production in filamentous fungi
AbstractFilamentous fungi are able to produce a wide range of valuable proteins and enzymes for many industrial applications. Recent advances in...
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Multiple roles played by the mitochondrial citrate carrier in cellular metabolism and physiology
The citrate carrier (CIC) is an integral protein of the inner mitochondrial membrane which catalyzes the efflux of mitochondrial citrate (or other...
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Mathematical Simulation of Electron Transport in the Primary Photosynthetic Processes
AbstractSummarized results of investigation of regulation of electron transport and associated processes in the photosynthetic membrane using methods...
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MDR/PGP Auxin Transport Proteins and Endocytic Cycling
Auxin is an essential regulator of plant growth and development. Polarized transport of auxin is responsible for apical dominance, tropic growth,...
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Mitochondria regulate intracellular coenzyme Q transport and ferroptotic resistance via STARD7
Coenzyme Q (or ubiquinone) is a redox-active lipid that serves as universal electron carrier in the mitochondrial respiratory chain and antioxidant...
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HDCR-katalysierte Hydrogenierung von CO2 zum H2-Carrier Ameisensäure
Hydrogen is considered as a game changer in decarbonization and combating global warming crisis. However, transport and storage of the gas are still...
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Protein–Protein Interactions in Neurodegenerative Diseases
Neurodegeneration is a state of progressive decay of neuronal structure and function. It has gained scientific attention owing to the fact that...
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Cytoplasmic mRNA Transport: Adaptors of mRNA Binding to Microtubule Motor Proteins
AbstractThe process of mRNA localization in the cytoplasm involves the directed transport of mRNP particles using the microtubule system. This...
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Regulation of zinc-dependent enzymes by metal carrier proteins
Zn 2+ ions are essential in many physiological processes, including enzyme catalysis, protein structural stabilization, and the regulation of many...
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Transcriptional and metabolic effects of aspartate-glutamate carrier isoform 1 (AGC1) downregulation in mouse oligodendrocyte precursor cells (OPCs)
Aspartate–glutamate carrier isoform 1 (AGC1) is a carrier responsible for the export of mitochondrial aspartate in exchange for cytosolic glutamate...
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Cadmium transport by mammalian ATP-binding cassette transporters
Cellular responses to toxic metals depend on metal accessibility to intracellular targets, reaching interaction sites, and the intracellular metal...
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Autophagy initiation triggers p150Glued–AP-2β interaction on the lysosomes and facilitates their transport
The endocytic adaptor protein 2 (AP-2) complex binds dynactin as part of its noncanonical function, which is necessary for dynein-driven...
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Hem25p is required for mitochondrial IPP transport in fungi
Coenzyme Q (CoQ, ubiquinone) is an essential cellular cofactor composed of a redox-active quinone head group and a long hydrophobic polyisoprene...
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Polyvinylamine and Its Derivative as Effective Carrier for Targeted Delivery of Small RNAs
Polymeric delivery systems could enable the fast- and low-side-effect transport of various RNA classes. Previously, we demonstrated that...
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Mechanisms of Water and Solute Transport
Movement of water and solutes from soil up to the seed tissue is one of the first processes occurring during seed germination. Mature seeds contain...