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The Effect of Peroxynitrite and tert-Butyl Hydroperoxide on Thiol Ligands of Dinitrosyl Iron Complexes
Low-molecular-weight dinitrosyl iron complexes (DNICs) with thiol-containing ligands are a physiological form for deposit and transport of nitric...
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Effects of Tl+ on the inner membrane thiol groups, respiration, and swelling in succinate-energized rat liver mitochondria were modified by thiol reagents
The effects of both Tl + and thiol reagents were studied on the content of the inner membrane free SH-groups, detected with Ellman reagent, and the...
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Thiol Redox Proteomics for Identifying Redox-Sensitive Cysteine Residues Within the Protein of Interest During Stress
Redox modulation is a common posttranslational modification to regulate protein activity. The targets of oxidizing agents are cysteine...
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Dietary-derived vitamin B12 protects Caenorhabditis elegans from thiol-reducing agents
BackgroundOne-carbon metabolism, which includes the folate and methionine cycles, involves the transfer of methyl groups which are then utilised as a...
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Synthesis and Anti-Tubercular (Tb) Evaluation of Bis[4-Ethylidineamino[1,2,4]Triazole-3-Thiol] Tethered by 1,4-Dihydropyridine
AbstractA new series of 5,5'-(2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3,5-diyl)bis[4-(ethylideneamino)-4 H -[1,2,4]-triazole-3-thiol) was...
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The Role of Organic Acids and Thiol Compounds in Detoxification and Tolerance of Zn Stress in Two Populations of Harmel
AbstractThe present study aimed to investigate the effects of Zn exposure (0, 1, 5, 15, 30 ppm Zn) on harmel seedlings. Two populations...
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Nitric oxide and AMF-mediated regulation of soil enzymes activities, cysteine-H2S system and thiol metabolites in mitigating chromium (Cr (VI)) toxicity in pigeonpea genotypes
Cr (VI) hampers plant growth and yield by reducing essential nutrient uptake as it competes for phosphate and sulfate transporters. Nitric oxide (NO)...
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Redox proteomic study of Bacillus cereus thiol proteome during fermentative anaerobic growth
BackgroundBacillus cereus is a notorious foodborne pathogen, which can grow under anoxic conditions. Anoxic growth is supported by endogenous redox...
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Role of Free Catecholamine in Thiol-Ene Crosslinking for Hyaluronic Acid Hydrogels with High Loading Efficiency of Anticancer Drugs
Background:Hyaluronic acid (HA) is a widely used polysaccharide in biomedical field because of its excellent biocompatibility. Its chemical structure...
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Intra- and Extra-cellular Thiol–Disulfide Homeostasis in Blood of Patients with Alcohol Use Disorder
AbstractAlcohol use disorder (AUD) is the loss of a person's quality of life due to increased alcohol consumption and the failure of alcohol...
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Prospects of Bacillus amyloliquefaciens (MZ945930) Mediated Enhancement of Capsicum annuum L. Plants Under Stress of Alternaria alternata in Terms of Physiological Traits, Thiol Content, Antioxidant Defense, and Phytohormones
Plants encounter many biotic entities, such as fungi, bacteria, and nematodes, which induce biotic stress that disrupts normal metabolism and limits...
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Two Fe mining sub-products and three thiol compounds alleviate Fe deficiency in soybean (Glycine max L.) grown in a calcareous soil in greenhouse conditions
PurposeThe aim of this work was to test the hypothesis that Fe mining sub-products and thiols can alleviate a moderate Fe-deficiency in the Strategy...
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The association of fasting plasma thiol fractions with body fat compartments, biomarker profile, and adipose tissue gene expression
People with high plasma total cysteine (tCys) have higher fat mass and higher concentrations of the atherogenic apolipoprotein B (apoB). The...
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The thiol-disulfide exchange activity of AtPDI1 is involved in the response to abiotic stresses
BackgroundArabidopsis protein disulfide isomerase 1 ( At PDI1) has been demonstrated to have disulfide isomerase activity and to be involved in the...
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Determination of low molecular thiols and protein sulfhydryl groups using heterocyclic disulfides
A promising area in the analytical chemistry of thiol-containing compounds is the use of heterocyclic disulfides as analytical agents, but now only a...
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Nitrosonium Cation as a Cytotoxic Component of Dinitrosyl Iron Complexes with Thiol-containing Ligands (based on the Experimental Work on MCF7 Human Breast Cancer Cell Culture)
Here we demonstrate that binuclear dinitrosyl iron complexes with thiol-containing ligands (glutathione and mercaptosuccinate, B-DNIC-GSH and...
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A quantitative thiol reactivity profiling platform to analyze redox and electrophile reactive cysteine proteomes
Cysteine is unique among all protein-coding amino acids, owing to its intrinsically high nucleophilicity. The cysteinyl thiol group can be covalently...
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Differential responses of thiol metabolism and genes involved in arsenic detoxification in tolerant and sensitive genotypes of bioenergy crop Ricinus communis
Castor, a non-food, dedicated bioenergy crop, has immense potential to be used for phytoremediation/revegetation of heavy metal contaminated sites....
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Thiol-trap** natural products under the lens of the cysteamine assay: friends, foes, or simply alternatively reversible ligands?
The literature on thia-Michael acceptors is vast and can be cherry-picked to show either that these compounds pollute chemical libraries displaying...
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Synthesis of Antimicrobial Lipopeptides Using the “CLipPA” Thiol-Ene Reaction
Cysteine Lipidation on a Peptide or Amino acid (CLipPA) technology provides a facile method for the lipidation of unprotected peptides containing a...