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The CssRS two-component system of Bacillus subtilis contributes to teicoplanin and polymyxin B response
CssRS is a two-component system that plays a pivotal role in mediating the secretion stress response in Bacillus subtilis . This system upregulates...
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Comparative activities of ampicillin and teicoplanin against Enterococcus faecalis isolates
BackgroundEnterococcus faecalis remains one of the most common pathogens causing infection in surgical patients. Our goal was to evaluate the...
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Transcriptional Response of vanB Operon in Staphylococcus aureus Against Vancomycin and Teicoplanin Stress
Staphylococcus aureus is a global pathogen and is responsible for causing severe life-threatening infections. The current study was designed to...
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In vitro synergistic activity of colistin and teicoplanin combination against multidrug-resistant Acinetobacter spp
Drug combinations may have a crucial role in treating infections due to multidrug resistant Acinetobacter spp . One suggested combination is colistin...
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Virulence and intermediate resistance to high-end antibiotic (teicoplanin) among coagulase-negative staphylococci sourced from retail market fish
This study reports the distribution of enterotoxigenic determinants among staphylococci and the susceptibility of staphylococci to various classes of...
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Evaluation of Teicoplanin Resistance Detected by Automated System in Coagulase Negative Staphylococci: A Comparison with Gradient Test and Broth Microdilution Methods
Upon the observation of an increase in teicoplanin resistance rates in coagulase negative staphylococci (CoNS) isolates determined by the automated...
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Teicoplanin biosynthesis: unraveling the interplay of structural, regulatory, and resistance genes
Teicoplanin (Tcp) is a clinically relevant glycopeptide antibiotic (GPA) that is produced by the actinobacterium Actinoplanes teichomyceticus. Tcp is...
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Inhibitory effects of aptamer targeted teicoplanin encapsulated PLGA nanoparticles for Staphylococcus aureus strains
Emergence of resistance to traditional antibiotic treatments necessitates alternative delivery systems. Teicoplanin is a glycopeptide antibiotic used...
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N-Terminal guanidine derivatives of teicoplanin antibiotics strongly active against glycopeptide resistant Enterococcus faecium
Antibiotic resistance is one of the major challenges in healthcare of our time. To meet this challenge, we designed and prepared guanidine and...
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Genetic insights into the mechanism of teicoplanin self-resistance in Actinoplanes teichomyceticus
Actinoplanes teichomyceticus NRRL B-16726 is the only known producer of the clinically important glycopeptide antibiotic teicoplanin. The producing...
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Improvement of the conjugation transfer of N. gerenzanensis based on the synergistic effect of quorum sensing and antibiotic interference
Nonomuraea gerenzanensis ( N. gerenzanensis ) is known for its ability to biosynthesize A40926, the precursor of the glycopeptide antibiotic (GPA)...
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Vancomycin heteroresistance among methicillin-resistant clinical isolates S. haemolyticus, S. hominis, S. simulans, and S. warneri
Besides being an essential part of the skin microbiome, coagulase-negative staphylococci are the etiological factors of serious infections. The aim...
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Antibiotic repurposing: bis-catechol- and mixed ligand (bis-catechol-mono-hydroxamate)-teicoplanin conjugates are active against multidrug resistant Acinetobacter baumannii
Antibiotics that are normally used to treat infections caused by Gram-positive bacteria might be made effective against Gram-negative bacterial...
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Detection and molecular characterization of VRE isolates in Slovakia from stool samples positive for Clostridioides difficile toxins
The study aimed to identify colonized patients as a possible source of eventual VRE (vancomycin-resistant enterococci) infection from stool samples...
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Characteristics of Clostridioides difficile isolates circulating in the Slovak hospitals
Clostridioides difficile is a frequent cause of hospital-acquired diarrhea associated with antibiotics. Hypervirulent strains of Clostridioides...
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Genetic description of VanD phenotype vanA genotype in vancomycin-resistant Enterococcus faecium isolates from a Bone Marrow Transplantation Unit
BackgroundVancomycin-resistant Enterococcus faecium (VREfm) is an important agent of hospital-acquired infection. VanA phenotype is characterized by...
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Prevalence and Antibiotic Resistance Patterns of Methicillin-Resistant Staphylococcus aureus (MRSA) in a Hospital Setting: A Retrospective Study from 2018 to 2022
Methicillin-resistant Staphylococcus aureus (MRSA) is a highly infectious pathogen that poses a serious threat to human life and health. This study...
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Regulation of teicoplanin biosynthesis: refining the roles of tei cluster-situated regulatory genes
Teicoplanin is a frontline glycopeptide antibiotic produced by Actinoplanes teichomyceticus . It is used to treat complicated cases of infection,...
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New semisynthetic teicoplanin derivatives have comparable in vitro activity to that of oritavancin against clinical isolates of VRE
Ten analogues of a teicoplanin pseudoaglycon derivative have been synthesized with the aim of optimizing the in vitro activity of the compound...
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Biofilm-producing ability of methicillin-resistant Staphylococcus aureus clinically isolated in China
BackgroundStaphylococcus aureus , a commensal bacterium, colonizes the skin and mucous membranes of approximately 30% of the human population. Apart...
