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Purification and characterization of L-arginine deiminase from Penicillium chrysogenum
L-arginine deiminase (ADI, EC 3.5.3.6) hydrolyzes arginine to ammonia and citrulline which is a natural supplement in health care. ADI was purified...
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Arsenic and Tau Phosphorylation: a Mechanistic Review
Arsenic poisoning can affect the peripheral nervous system and cause peripheral neuropathy. Despite different studies on the mechanism of...
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Biofabricated yeast: super-soldier for detoxification of heavy metals
The advances in nanotechnology have shown enormous impacts in environmental technology as a potent weapon for degradation of toxic organic pollutants...
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Rapid reconstitution of ubiquitinated nucleosome using a non-denatured histone octamer ubiquitylation approach
BackgroundHistone ubiquitination modification is emerging as a critical epigenetic mechanism involved in a range of biological processes. In vitro...
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Peptides as Vectors for Radiopharmaceutical Therapy
Radiolabeled receptor-binding peptides enable the selective delivery of radionuclides to target tissues (e.g., tumor) while reducing radiation...
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Determination of Drug-to-Antibody Ratio of ADCs
The drug-to-antibody ratio (DAR) refers to the number of small toxic molecules per antibody in the antibody-drug conjugates (ADCs). DAR can directly...
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Study on Modification of Paclitaxel and Its Antitumor Preparation
AbstractPaclitaxel (PTX) was discovered more than 50 years ago in 1968. The drug, known as the first herbal-derived chemotherapeutic drug approved,...
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Gold Nanoparticles-Based Point-of-Care Colorimetric Diagnostic for Plant Diseases
Plant diseases caused by pathogens such as fungi, viruses, and bacteria create a substantial loss worldwide that leads to a severe threat to food...
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Protein Chemistry and Gelation
Proteins are macromolecules involved in practically all biological processes. Regardless of their structural or functional role, all proteins are...
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The Role of AM Fungi in the Alleviation of Cadmium Stress in Crops
The symbiotic relationship between crop species and arbuscular mycorrhizal (AM) fungi is crucial for plant health, productivity, and environmental...
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Mycotoxins as Food and Feed Contaminant: Effect on Health and Economy and Their Management
Mycotoxins are toxic compounds that are naturally produced by certain fungi in numerous foodstuffs such as cereals, dried fruits, nuts, and spices....
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Are cysteine residues of human phospholipid scramblase 1 essential for Pb2+ and Hg2+ binding-induced scrambling of phospholipids?
Lead and mercury being common environmental pollutants are often associated with erythrocytes, where phosphatidylserine (PS) exposure-mediated...
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Heat Stress in Wheat: Adaptation Strategies
Globally wheat productivity is affected due to unfavorable effects of different biotic and abiotic stresses. Combating these stresses to minimize the...
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Naturally occurring glucosinolates and isothiocyanates as a weapon against chronic pain: potentials and limits
Investigation into glucosinolates (GLs) therapeutic effects boasts a long history, which began with the evidence that their hydrolysis-derived...
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Biochemical characterization of extremozyme L-asparaginase from Pseudomonas sp. PCH199 for therapeutics
L-asparaginase (L-ASNase) from microbial sources is a commercially vital enzyme to treat acute lymphoblastic leukemia. However, the side effects...
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Serum Cadmium Levels and Risk of Metabolic Syndrome: A Cross-Sectional Study
The increase in the prevalence of metabolic disorders globally is becoming a public health concern. Previous studies have reported an association...
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The converging path of protein SUMOylation in phytohormone signalling: highlights and new frontiers
Key messageThe intersection of phytohormone signalling pathways with SUMOylation, a key post-translational modification, offers an additional layer...
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Super Sweet and Taste Modifier Proteins
It has been found that super sweet (SS) proteins are thousands times sweeter than sucrose, required in a very small amount to sweeten the food...
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Fundamentals of redox regulation in biology
Oxidation–reduction (redox) reactions are central to the existence of life. Reactive species of oxygen, nitrogen and sulfur mediate redox control of...
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Collective Learnings of Studies of Stress Granule Assembly and Composition
Stress granules have gained considerable exposure and interest in recent years. These micron-sized entities, composed of RNA and protein, form...