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Biochemical characterization of a novel β-galactosidase from Pedobacter sp. with strong transglycosylation activity at low lactose concentration
A novel β-galactosidase gene ( PbBgal35A ) from Pedobacter sp. CAUYN2 was cloned and expressed in Escherichia coli . The gene had an open reading frame...
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A potent ion channel blocker, hydroquinidine, exhibits strong anti-cancer activity on colon, pancreatic, and hepatocellular cancer cells
BackgroundDespite recent advances in drug discovery, cancer is still one of the most lethal health problems worldwide. In most cases, standard...
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Tumor selective Ru(III) Schiff bases complexes with strong in vitro activity toward cisplatin-resistant MDA-MB-231 breast cancer cells
Novel ruthenium(III) complexes of general formula Na[RuCl 2 (L 1−3 -N,O) 2 ] where L (1–3) denote deprotonated Schiff bases (HL 1 -HL 3 ) derived from...
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Effect of Strong Light on Chlorophyll Degradation in Strawberry Leaves
AbstractStrawberry seedlings are often subjected to strong light stress during breeding and strawberry production, leading to seedling death, sunburn...
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Activity Patterns of American Marsupials
New World marsupials have a striking diversity of activity patterns. Until now, knowledge on diel activity was normally granted by means of simple... -
Evaluation of the Moonlighting Histone H3 Specific Protease (H3ase) Activity and the Dehydrogenase Activity of Glutamate Dehydrogenase (GDH)
The N-terminus of Histone H3 is proteolytically processed in aged chicken liver. A histone H3 N-terminus specific endopeptidase (named H3ase) has...
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Strong culm: a crucial trait for develo** next-generation climate-resilient rice lines
Lodging, a phenomenon characterized by the bending or breaking of rice plants, poses substantial constraints on productivity, particularly during the...
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Nocturnality and Activity Budgets of Owl Monkeys in Tropical Ecosystems
The subtropical populations of owl monkeys (Aotus) and some lemurs have flexible patterns that include activity during both day and night. Early... -
Antimicrobial Activity of Capsaicin and Its Derivatives
Chilies contain a special group of alkaloids called capsaicinoids, which are synthesized as secondary metabolites and are responsible for the... -
Physical Activity Across the Life Span: Personality, Physical Activity, and Sedentary Behavior
In this chapter, the prevalence of physically activity as well as sedentary behavior across the life span is presented. Empirical findings on the... -
Assay of DAGLα/β Activity
The endocannabinoid 2-arachidonoylglycerol (2-AG) exerts its physiological action by binding to and functionally activating type-1 (CB1) and type-2... -
Enzyme Identification and Screening: Activity-Based Methods
Methods for the identification and characterization of “ideal” enzymes for industrial use in the field of biotechnology have developed rapidly in... -
Assay of Monoacylglycerol Lipase Activity
Monoacylglycerol lipase (MGL/MAGL/MGLL) is a serine hydrolase involved in the biological deactivation of the endocannabinoid... -
Absence of calcium-sensing receptor basal activity due to inter-subunit disulfide bridges
G protein-coupled receptors naturally oscillate between inactive and active states, often resulting in receptor constitutive activity with important...
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Synthesis and Antitumor Activity Study of Novel Formononetin Derivatives
AbstractObjective: In order to enrich the library of anti-tumor small molecule compounds, 8 compounds, with highly effective antitumor, have been...
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Assessing the Activity of Transcription Factor FoxO1
The transcription factor FoxO1 (forkhead box O1) regulates genes that are involved in development, metabolism, cellular innovation, longevity, and... -
Snake venom phospholipase A2s exhibit strong virucidal activity against SARS-CoV-2 and inhibit the viral spike glycoprotein interaction with ACE2
The COVID-19 pandemic caused by SARS-CoV-2 requires new treatments both to alleviate the symptoms and to prevent the spread of this disease. Previous...
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Characterization of Phytaspase Proteolytic Activity Using Fluorogenic Peptide Substrates
Within the subtilase family of plant proteolytic enzymes, phytaspases are distinguished by their strict substrate cleavage specificity after an... -
Antioxidant Activity of Essential Oils: A Mechanistic Approach
Essential oils (EOs) have long been extracted using a variety of techniques from different aromatic and therapeutic plants. Because of their... -
Physical Activity, Subjective Well-Being and Mental Health
Although the empirical evidence for positive associations between physical activity, well-being, and mental health has improved in recent years,...