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  1. Autophagy regulates sex steroid hormone synthesis through lysosomal degradation of lipid droplets in human ovary and testis

    Autophagy is an evolutionarily conserved process that aims to maintain the energy homeostasis of the cell by recycling long-lived proteins and...

    Yashar Esmaeilian, Francesko Hela, ... Ozgur Oktem in Cell Death & Disease
    Article Open access 26 May 2023
  2. Steroid hormone-dependent changes in trehalose physiology in the silkworm, Bombyx mori

    Holometabolous insects undergo metamorphosis to reconstruct their body to the adult form during pupal period. Since pupae cannot take any diets from...

    Takumi Suzuki, Chika Akiba, ... Masafumi Iwami in Journal of Comparative Physiology B
    Article 23 May 2023
  3. Hormone und Mediatoren

    Hormone dienen, zusammen mit den Wachstumsfaktoren, zur extrazellulären Signalübermittlung. Die strukturell heterogenen Hormone werden in...
    Philipp Christen, Rolf Jaussi, Roger Benoit in Biochemie und Molekularbiologie
    Chapter 2024
  4. Exposure to Fluoride From in Utero to Puberty Alters Gonadal Structure and Steroid Hormone Expression in Offspring Rats

    The reproductive toxicity of fluoride has been proven by a large number of studies. While the underlying mechanism of reproductive toxicity during...

    Wanpan Li, Zilong Sun, ... Jundong Wang in Biological Trace Element Research
    Article 21 April 2022
  5. Effects of 4-vinylcyclohexene diepoxide on the cell cycle, apoptosis, and steroid hormone secretion of goat ovarian granulosa cells

    4-Vinylcyclohexene diepoxide (VCD) is a potentially hazardous industrial chemical that may enter a goat’s body in various ways during industrial...

    Yuyang Miao, Wen**g Wan, ... Qiang Wei in In Vitro Cellular & Developmental Biology - Animal
    Article 01 March 2022
  6. The multifaceted therapeutic value of targeting steroid receptor coactivator-1 in tumorigenesis

    Steroid receptor coactivator-1 (SRC-1, also known as NCOA1) frequently functions as a transcriptional coactivator by directly binding to...

    Qiang Chen, Peng Guo, ... Chundong Yu in Cell & Bioscience
    Article Open access 29 March 2024
  7. Juvenil- und Steroid-Hormone

    Ausgehend von der Mevalonsäure wird in Vertebraten und Invertebraten aus Isoprenyloligomeren, Squalen und Cholesterin eine Vielzahl von Hormonen...
    Bernhard Kleine, Winfried G. Rossmanith in Hormone und Hormonsystem - Lehrbuch der Endokrinologie
    Chapter 2021
  8. Thyroid and Sex Steroid Hormone Level in the Pink Salmon Oncorhynchus gorbuscha during Marine and Freshwater Periods of Spawning Migration

    Abstract

    Thyroid and sex steroid hormones have been studied in spawners of the pink salmon Oncorhynchus gorbuscha at the stage of changing the...

    E. D. Pavlov, E. V. Ganzha, D. S. Pavlov in Journal of Ichthyology
    Article 15 June 2022
  9. Effect of liver receptor homolog-1 on cell apoptosis and steroid hormone secretion on granulosa cells from Hu sheep

    The apoptosis of granulosa cells can result in follicular atresia, a key process in follicle selection and development. The related molecular...

    Jie Wang, Guijiang Xu, ... Wei Zhang in In Vitro Cellular & Developmental Biology - Animal
    Article 06 January 2022
  10. Role of sex hormone-binding globulin in the free hormone hypothesis and the relevance of free testosterone in androgen physiology

    According to the free hormone hypothesis, biological activity of a certain hormone is best reflected by free rather than total hormone...

    N. Narinx, K. David, ... D. Vanderschueren in Cellular and Molecular Life Sciences
    Article 07 October 2022
  11. The Effects of Sex Steroid Hormones on Cardiovascular Physiology in Females

    There are fundamental sex-specific differences in cardiovascular (CV) physiology and cardiovascular disease (CVD) pathophysiology. Estrogen, a sex...
    Nicole L. Tegg, Caitlynd Myburgh, Colleen M. Norris in Biology of Women’s Heart Health
    Chapter 2023
  12. Synthesis of Steroid Tracers by an Oxime Ligation Method and Their Use in Fluorescent Polarisation Immunoassay

    Abstract

    ctive: The development of a fast and reliable method for the quantitative evaluation of steroid hormones is very relevant for scientific and...

    I. A. Prokhorenko, D. A. Glushchenko, ... S. A. Eremin in Russian Journal of Bioorganic Chemistry
    Article 13 February 2024
  13. Aging induces region-specific dysregulation of hormone synthesis in the primate adrenal gland

    Adrenal glands, vital for steroid secretion and the regulation of metabolism, stress responses and immune activation, experience age-related decline,...

    Qiaoran Wang, Xuebao Wang, ... Weiqi Zhang in Nature Aging
    Article 19 March 2024
  14. Gut microbiota affects the estrus return of sows by regulating the metabolism of sex steroid hormones

    Background

    Sex hormones play important roles in the estrus return of post-weaning sows. Previous studies have demonstrated a complex and...

    Min Liu, Jia Zhang, ... Lusheng Huang in Journal of Animal Science and Biotechnology
    Article Open access 20 December 2023
  15. Mobilization of cholesterol induces the transition from quiescence to growth in Caenorhabditis elegans through steroid hormone and mTOR signaling

    Recovery from the quiescent developmental stage called dauer is an essential process in C. elegans and provides an excellent model to understand how...

    Kathrin Schmeisser, Damla Kaptan, ... Teymuras V. Kurzchalia in Communications Biology
    Article Open access 24 January 2024
  16. Omega-6 highly unsaturated fatty acids in Leydig cells facilitate male sex hormone production

    Highly unsaturated fatty acids (HUFAs) are fatty acids with more than three double bonds in the molecule. Mammalian testes contain very high levels...

    Keiken Ri, Hyeon-Cheol Lee-Okada, Takehiko Yokomizo in Communications Biology
    Article Open access 21 September 2022
  17. Sex differences in colorectal cancer: with a focus on sex hormone–gut microbiome axis

    Sexual dimorphism has been observed in the incidence and prognosis of colorectal cancer (CRC), with men generally exhibiting a slightly higher...

    Zihong Wu, Yuqing Huang, ... Xueke Li in Cell Communication and Signaling
    Article Open access 07 March 2024
  18. The steroid hormone estriol (E3) regulates epigenetic programming of fetal mouse brain and reproductive tract

    Background

    Estriol (E 3 ) is a steroid hormone formed only during pregnancy in primates including humans. Although E 3 is synthesized at large amounts...

    Yu** Zhou, Baoxia Gu, ... Hugh S. Taylor in BMC Biology
    Article Open access 02 May 2022
  19. EP300/CREBBP acetyltransferase inhibition limits steroid receptor and FOXA1 signaling in prostate cancer cells

    The androgen receptor (AR) is a primary target for treating prostate cancer (PCa), forming the bedrock of its clinical management. Despite their...

    Jasmin Huttunen, Niina Aaltonen, ... Ville Paakinaho in Cellular and Molecular Life Sciences
    Article Open access 02 April 2024
  20. Adrenarche-accompanied rise of adrenal sex steroid precursors prevents NAFLD in Young Female rats by converting into active androgens and inactivating hepatic Srebf1 signaling

    Background

    Non-alcoholic fatty liver disease (NAFLD) has rapidly become the most common cause of chronic liver disease in children and adolescents,...

    Haoqing Li, Yingyu Liu, ... **ngfa Han in BMC Genomics
    Article Open access 19 February 2024
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