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An array of signal-specific MoYpd1 isoforms determines full virulence in the pathogenic fungus Magnaporthe oryzae
Magnaporthe oryzae is placed first on a list of the world’s top ten plant pathogens with the highest scientific and economic importance. The locus...
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Effect of IgG Fc-fusion and KDEL-ER retention signal on prostate-specific antigen expression in plant and its immune in mice
Prostate-specific antigen (PSA) is a protein highly expressed in cancer cells of the prostate gland. In this study, the PSA recombinant protein was...
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The Yellow-breasted Barbet (Trachyphonus margaritatus) introduces vocal duets and choruses with a specific multimodal signal, during territorial advertisement
Cooperative behaviour is a prominent feature among many group-living species and continues to pose challenges to our understanding about the...
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Co-fitness analysis identifies a diversity of signal proteins involved in the utilization of specific c-type cytochromes
Purposec -Type cytochromes are essential for extracellular electron transfer (EET) in electroactive microorganisms. The expression of appropriate c -ty...
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Thyramide Signal Amplification: New Opportunities for DNA in Situ Hybridization
Abstract —DNA in situ hybridization (ISH) is a valuable technique in molecular cytogenetics for precisely localizing specific DNA sequences on...
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Meta-analysis defines predominant shared microbial responses in various diseases and a specific inflammatory bowel disease signal
BackgroundGut microbial alteration is implicated in inflammatory bowel disease but is noted in other diseases. Systematic comparison to define...
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Signal transduction in plant cold acclimation
Temperate plants respond to low temperature by activating a cold acclimation program leading to enhanced tolerance to freezing temperatures. This... -
Auditory Adaptation to Speech Signal Characteristics
AbstractThe review presents experimental data on auditory adaptation to specific speech parameters—temporal (tempo-rhythmic) and...
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Signal Transduction Immunohistochemistry Methods and Protocols
This new edition collects diverse protocols compiled by experts from different areas of research as well as by biotech researchers develo** novel... -
Using residual regressions to quantify and map signal leakage in genomic prediction
BackgroundMost genomic prediction applications in animal breeding use genotypes with tens of thousands of single nucleotide polymorphisms (SNPs)....
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Towards in silico CLIP-seq: predicting protein-RNA interaction via sequence-to-signal learning
We present RBPNet, a novel deep learning method, which predicts CLIP-seq crosslink count distribution from RNA sequence at single-nucleotide...
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Secondary Metabolites of Bifido- and Lactobacteria Fulfilling Signal Functions
AbstractThe culture liquid of lactic-acid bacteria (LABs) and bifidobacteria contained secondary metabolites fulfilling signal functions, such as...
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Neuromuscular Signal Transmission
The intricate architecture of skeletal muscle, characterized by myriad fibers with distinct functional and metabolic properties, plays a pivotal role... -
Rainforest birds avoid biotic signal masking only in cases of high acoustic saturation
Acoustic signaling among birds is central to intra-species communication, courtship, and reproductive success, and so habitat suitability is...
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Enhancing Human Glycoprotein Hormones Production in CHO Cells Using Heterologous Beta-Chain Signal Peptides
AbstractWe studied the influence of heterologous signal peptides in the β-chains of glycoprotein hormones on the biosynthesis of these hormones in a...
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A signal transmission strategy driven by gap-regulated exonuclease hydrolysis for hierarchical molecular networks
Exonucleases serve as efficient tools for signal processing and play an important role in biochemical reactions. Here, we identify the mechanism of...
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A phase separation-fortified bi-specific adaptor for conditional tumor killing
A common approach in therapeutic protein development involves employing synthetic ligands with multivalency, enabling sophisticated control of signal...
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ZBP1 condensate formation synergizes Z-NAs recognition and signal transduction
Z-DNA binding protein 1 (ZBP1) is a crucial player in the intracellular recognition of Z-form nucleic acids (Z-NAs) through its Zαβ domain,...
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Signal Perception and Transduction Mechanisms
While investigating the effect of unilateral light on the bending response of canary grass (Phalaris canariensis) seedlings, Charles Darwin (1881)... -
Oncogenic Kras induces spatiotemporally specific tissue deformation through converting pulsatile into sustained ERK activation
Tissue regeneration and maintenance rely on coordinated stem cell behaviours. This orchestration can be impaired by oncogenic mutations leading to...