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An Integrated Bayesian-Heuristic Semiotic Model for Understanding Human and SARS-CoV-2 Representational Structures
The aim of this paper is to explore the connections between semiotics and biology by examining the behaviors of both humans and non-cognizant agents,...
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The historical nature of biological complexity and the ineffectiveness of the mathematical approach to it
Contemporary scientific knowledge is built on both methodological and epistemological reductionism. The discovery of the limitations of the...
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The information theory of individuality
Despite the near universal assumption of individuality in biology, there is little agreement about what individuals are and few rigorous quantitative...
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Prehistoric Stone Projectile Points and Technological Convergence
Stone tools are found throughout the archaeological record left by humans and their ancestors beginning as much as 2.6–3.4 million years ago. Given... -
The Problems of Replication in the Early Stages of Evolution: Enumeration of Variants and Spatial Configurations of Replicators
Two main problems of replication in the early stages of evolution are discussed: the problem of exponentially large number of conformational degrees...
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In silico ribozyme evolution in a metabolically coupled RNA population
BackgroundThe RNA World hypothesis offers a plausible bridge from no-life to life on prebiotic Earth, by assuming that RNA, the only known molecule...
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Paradoxes of Early Stages of Evolution of Life and Biological Complexity
Two of the most fundamental questions concerning the origin of life, how biologically important molecules (RNA, proteins) find their unique spatial...
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Networks and Hierarchies: Approaching Complexity in Evolutionary Theory
This expansion of the hierarchy theory of evolution provides a new perspective in which biological phenomena are conceptualized. In this work, we (1)... -
Time: The Biggest Pattern in Natural History Research
We distinguish between four cosmological transitions in the history of Western intellectual thought, and focus on how these cosmologies...
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Visualizing Macroevolution: From Adaptive Landscapes to Compositions of Multiple Spaces
The adaptive landscape is an important diagrammatic concept that was conceived in population genetics. During the Modern Synthesis, in the first half... -
Defining and simulating open-ended novelty: requirements, guidelines, and challenges
The open-endedness of a system is often defined as a continual production of novelty. Here we pin down this concept more fully by defining several...
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First Movement. Life as a Cosmic Imperative
A recent reformulation of the second law of thermodynamics in terms of the “maximum entropy production principle” allows a novel view of cosmic... -
Origins and Emergent Evolution of Life: The Colloid Microsphere Hypothesis Revisited
Self-replicating molecules, in particular RNA, have long been assumed as key to origins of life on Earth. This notion, however, is not very secure...
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The Extended Synthesis: The Law of the Conditions of Existence
A unified theory of biology must incorporate a naturalistic explanation for the origin of life, namely that given certain conditions, it was highly...
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Manipulating Representations
The present paper proposes a definition for the complex polysemic concepts of consciousness and awareness (in humans as well as in other species),...
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Homochirality in Life: Two Equal Runners, One Tripped
Strong arguments can be found in the literature addressed to the question of the origin of homochirality in life, supporting the hypothesis that...
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Evolution in biological and nonbiological systems under different mechanisms of generation and inheritance
The majority of definitions of life and evolution include the notion that part of an organism has to be copied to its offspring and that this...
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Spatial Models of Prebiotic Evolution: Soup Before Pizza?
The problem of information integration andresistance to the invasion of parasitic mutants in prebiotic replicator systemsis a notorious issue of...