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Inactivation of epithelial sodium ion channel molecules serves as effective diagnostic biomarkers in clear cell renal cell carcinoma
BackgroundNon-voltage-gated sodium channel, also known as the epithelial sodium channel (ENaC), formed by heteromeric complexes consisting of SCNN1A,...
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Sodium-Induced Calcium Signaling in Plants Under Salinity Stress
Global climate change is posing serious threat to agricultural productivity worldwide. Therefore, ensuring global food security in the light of...
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Introduction of a Sodium-Binding Motif into Subunits a and c of Bacillus sp. PS3 Proton F-ATPase Does Not Result in Sodium Specificity of the Enzyme
AbstractIn bacteria, F-type ATPase (F-ATPase) plays a key role in bioenergetics and couples ATP synthesis/hydrolysis with the transport of ions (H + ...
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Outlining cardiac ion channel protein interactors and their signature in the human electrocardiogram
Protein–protein interactions are essential for normal cellular processes and signaling events. Defining these interaction networks is therefore...
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Measurements of the Ion Channel Activity of the Transmembrane Stator Complex in the Bacterial Flagellar Motor
The bacterial flagellum is driven by a rotational motor located at the base of the flagellum. The stator unit complex conducts cations such as...
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Ion Compartmentalization Determines Salinity Tolerance in Olive Cultivars
Reduced availability and quality of water for irrigation have decreased olive growth and productivity in recent years. This study was conducted to...
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Functionally-selective inhibition of threshold sodium currents and excitability in dorsal root ganglion neurons by cannabinol
Cannabinol (CBN), an incompletely understood metabolite for ∆9-tetrahydrocannabinol, has been suggested as an analgesic. CBN interacts with...
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Sodium and Chloride Sensitivity in Alfalfa (Medicago sativa L.): Growth, Photosynthesis, and Tissue Ion Regulation in Contrasting Genotypes
Alfalfa ( Medicago sativa L.) is a moderately salt-tolerant plant. This study was conducted to evaluate responses of two contrasting alfalfa genotypes...
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Sodium as a subsidy in the spring: evidence for a phenology of sodium limitation
Understanding the factors that mediate carbon (C) cycling is increasingly important as anthropogenic activities and climate change alter ecosystems....
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Role of Phytomelatonin in Promoting Ion Homeostasis During Salt Stress
Salinity is one of the major abiotic factors limiting plant growth and agricultural productivity. Salt stress disrupts the ion compartmentalization...
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A DNA nanodevice for map** sodium at single-organelle resolution
Cellular sodium ion (Na + ) homeostasis is integral to organism physiology. Our current understanding of Na + homeostasis is largely limited to Na + ...
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Comparative genetic, biochemical and physiological analysis of sodium and chlorine in wheat
Plant with a great diversity shows several responses towards the biotic and abiotic stresses. Among these abiotic stresses, salinity is the main...
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Site-directed mutagenesis at the Glu78 in Ec-NhaA transporter impacting ion exchange: a biophysical study
Na + /H + antiporters facilitate the exchange of Na + for H + across the cytoplasmic membrane in prokaryotic and eukaryotic cells. These transporters are...
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Comparison of Halophyte and Glycophyte Plants from the Amaranthaceae-Chenopodiaceae Family in Their Ion-Exchange Properties of Polymeric Matrix of Cell Walls
AbstractIon-exchanging properties of the polymeric matrix of the cell walls isolated from leaves were examined. The glycophyte 55-day-old plants of...
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Use of Surface Plasmon Resonance Technique for Studies of Inter-domain Interactions in Ion Channels
Ion channels are transmembrane proteins essential for cellular functions and are important drug targets. Surface plasmon resonance (SPR) is a...
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Osa-miR1861e Modulates Sodium Toxicity Responses in Rice Immature Grains via OsGST and OsPILS7b
The microRNAs (miRNAs) have received considerable attention for their potential exploration in development of high-yielding, stress-resilient...
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Ion uptake in naturally acidic water
The first studies on ion regulation in fish exposed to low pH, which were inspired by the Acid Rain environmental crisis, seemed to indicate that ion...
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An Atomic Level Investigation of Sodium Ions Regulating Agonist and Antagonist Binding in the Active Site of a Novel Target 5HT2BR Against Drug-Resistant Epilepsy
The study investigates the movement of sodium ions inside the ligand-binding pocket of the class-A GPCR serotonin receptor (5HT 2B R), a primary target...
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Purification of Potassium Ion Channels Using Styrene–Maleic Acid Copolymers
Structural studies require the production of target proteins in large quantities and with a high degree of purity. For membrane proteins, the...
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Preparation, characterization, bacteriostatic efficacy, and mechanism of zinc/selenium-loaded sodium humate
AbstractIn recent years, metal-based complexes including selenium (Se) and zinc (Zn)-containing compounds have been widely explored for their...
