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Reconstructed Human Skin with Hypodermis Shows Essential Role of Adipose Tissue in Skin Metabolism
Background:Dysregulation of skin metabolism is associated with a plethora of diseases such as psoriasis and dermatitis. Until now, reconstructed...
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Characterization and biocompatibility evaluation of acellular rat skin scaffolds for skin tissue engineering applications
Utilization of acellular scaffolds, extracellular matrix (ECM) without cell content, is growing in tissue engineering, due to their high...
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How Skin Color Depends on Tissue Oxygenation
Background: Skin color is essential to skin and wound assessment as it brings valuable information about skin physiology and pathology. An approach,...
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Development of metabolome extraction strategy for metabolite profiling of skin tissue
IntroductionChanges in skin phenotypic characteristics are based on skin tissue. The study of the metabolic changes in skin tissue can help...
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Quality management overview for the production of a tissue-engineered human skin substitute in Malaysia
Treatments for skin injuries have recently advanced tremendously. Such treatments include allogeneic and xenogeneic transplants and skin substitutes...
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Fibroblast-activating potency of a hydrolysate of purified collagen and a tissue hydrolysate from sturgeon skin
Caviar is the primary marketable product of sturgeon aquaculture; therefore, other body parts, including the meat, are generally discarded after the...
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Single-stage transplantation combined with epidermal stem cells promotes the survival of tissue-engineered skin by inducing early angiogenesis
BackgroundThe composite transplantation of a split-thickness skin graft (STSG) combined with an acellular dermal matrix (ADM) is a promising repair...
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Investigation of memory influences on bio-heat responses of skin tissue due to various thermal conditions
Advancement of new technologies such as laser, focused ultrasound, microwave and radio frequency for thermal therapy of skin tissue has increased...
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Evaluation of secretomes derived from human dermal and adipose tissue mesenchymal stem/stromal cells for skin wound healing: not as effective as cells
BackgroundAlthough the paracrine effects of mesenchymal stem/stromal cells (MSCs) have been recognized as crucial mediators of their regenerative...
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Leveraging Tissue Engineering for Skin Cancer Models
Bioengineered in vitro three-dimensional (3D) skin model has emerged as a promising tool for recapitulating different types of skin cancer and...
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Tissue Concentration Analysis of Sulfur, Calcium and Oxygen in Novel Skin Primo Nodes After Acupuncture
Over the past 5000 years, acupuncture has been practiced in Korea, China, and Japan to relieve various diseases, and it is now widely used and...
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Transferosomes stabilized hydrogel incorporated rhodomyrtone-rich extract from Rhodomyrtus tomentosa leaf fortified with phosphatidylcholine for the management of skin and soft-tissue infections
Rhodomyrtus tomentosa leaf (RT)-incorporated transferosomes were developed with lecithin and cholesterol blends with edge activators at different...
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Bioengineered skin constructs based on mesenchymal stromal cells and acellular dermal matrix exposed to inflammatory microenvironment releasing growth factors involved in skin repair
BackgroundSkin tissue engineering is a rapidly evolving field of research that effectively combines stem cells and biological scaffolds to replace...
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Soft Tissue Reconstruction
Autologous fat transplantation has revolutionized soft tissue reconstruction, but conventional methods remain unpredictable as graft resorption rates...
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Mechanical stiffness promotes skin fibrosis via Piezo1-Wnt2/Wnt11-CCL24 positive feedback loop
Skin fibrosis is characterized by the excessive accumulation of extracellular matrix (ECM) caused by fibrotic disorders of the skin. In recent years,...
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Cellular and molecular mechanisms of skin wound healing
Wound healing is a complex process that involves the coordinated actions of many different tissues and cell lineages. It requires tight orchestration...
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Exosomes in skin photoaging: biological functions and therapeutic opportunity
Exosomes are tiny extracellular vesicles secreted by most cell types, which are filled with proteins, lipids, and nucleic acids (non-coding RNAs,...
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Aging and homeostasis of the hypodermis in the age-related deterioration of skin function
Adipose tissues in the hypodermis, the crucial stem cell reservoir in the skin and the endocrine organ for the maintenance of skin homeostasis...
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Quantification of age-related changes in the structure and mechanical function of skin with multiscale imaging
The mechanical properties of skin change during aging but the relationships between structure and mechanical function remain poorly understood....
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A keratinocyte-adipocyte signaling loop is reprogrammed by loss of BTG3 to augment skin carcinogenesis
Obesity is endemic to many developed countries. Overweight or obesity is associated with an increased risk of develo** cancer. Dysfunctional...
