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Enhancing Human Glycoprotein Hormones Production in CHO Cells Using Heterologous Beta-Chain Signal Peptides
AbstractWe studied the influence of heterologous signal peptides in the β-chains of glycoprotein hormones on the biosynthesis of these hormones in a...
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Identification of Extracellular Signal of Secretory Peptides in Cyanobacterium aponinum PCC10605 by In Silico Approach
Cyanobacteria are a suitable host for sustainable production of recombinant proteins owing to low-cost raw material requirement. The major challenge...
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Breaking the ‘don’t eat me’ signal: in silico design of CD47-directed peptides for cancer immunotherapy
The leading cause of death worldwide is cancer. Although there are various therapies available to treat cancer, finding a successful one can be like...
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Nuclear localization signal peptides enhance genetic transformation of Dunaliella salina
BackgroundDunaliella salina (D. salina) expression system shows a very attractive application prospect, but it currently has a technical bottleneck,...
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Untargeted Analysis of Short-Chain Peptides in Urine Samples Short Peptides Analysis
Short-chain peptides have attracted increasing attention in different research fields, including biomarker discovery, but also a well-known...
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Selenium deficiency increased duodenal permeability and decreased expression of antimicrobial peptides by activating ROS/NF-κB signal pathway in chickens
Selenium (Se) is an essential trace element for the body. Various organs of the body, including the intestine, are affected by its deficiency. Se...
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Real-time detection of 20 amino acids and discrimination of pathologically relevant peptides with functionalized nanopore
Precise identification and quantification of amino acids is crucial for many biological applications. Here we report a copper(II)-functionalized Mycoba...
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Identification of two plastid transit peptides for construction of pollen-inactivation system in rice
Hybrid seed production technology (SPT) is achieved through the utilization of a recessive nuclear male-sterile mutant transformed with a transgenic...
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Label-Free Quantitation of Endogenous Peptides
Liquid chromatography–mass spectrometry (LC-MS)-based peptidomics methods allow for the detection and identification of many peptides in a complex...
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Microbial Production of Bioactive Peptides
Bioactive peptides could be produced through diverse methodologies; nevertheless, the use of microbial cells remains an interesting strategy. A...
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SignalP 6.0 predicts all five types of signal peptides using protein language models
Signal peptides (SPs) are short amino acid sequences that control protein secretion and translocation in all living organisms. SPs can be predicted...
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Bioinformatics Methods for Prediction of Gene Families Encoding Extracellular Peptides
Genes encoding small secreted peptides are widely distributed among plant genomes but their detection and annotation remains challenging. The...
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Synergy between Winter Flounder antimicrobial peptides
Some antimicrobial peptides (AMPs) have potent bactericidal activity and are being considered as potential alternatives to classical antibiotics. In...
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Antimicrobial peptides: natural or synthetic defense peptides against HBV and HCV infections
According to the literature, treatment of HCV and HBV infections faces challenges due to problems such as the emergence of drug-resistant mutants,...
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Bioinspired peptides induce different cell death mechanisms against opportunistic yeasts
The management of fungal diseases imposes an urgent need for the development of effective antifungal drugs. Among new drug candidates are the...
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Small secreted peptides (SSPs) in tomato and their potential roles in drought stress response
Tomato ( Solanum lycopersicum ) is one of the most important vegetable crops in the world and abiotic stresses often cause serious problems in tomato...
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Design and evaluation of tadpole-like conformational antimicrobial peptides
Antimicrobial peptides are promising alternatives to conventional antibiotics. Herein, we report a class of “tadpole-like” peptides consisting of an...
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Antioxidant peptides from plants: a review
Bioactive peptides derived from plant protein sequences have a broad spectrum of biotechnological applications, including treating oxidation-related...
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Mobile Signaling Peptides: Secret Molecular Messengers with a Mighty Role in Plant Life
Adaptive mechanisms for unfavorable environments have evolved in plants for thousands of generations, primarily in the form of endogenous chemical...
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Subtilase-mediated biogenesis of the expanded family of SERINE RICH ENDOGENOUS PEPTIDES
Plant signalling peptides are typically released from larger precursors by proteolytic cleavage to regulate plant growth, development and stress...
