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Risk and Side Effects
Thinking outside the box can be helpful, in life as well as in soccer and the well known coach of the Freiburg soccer team Christian Streich is...
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Balancing Trait Improvement with Tradeoff Side-Effects Using Genome Editing Technology
Improving traits by breeding involves compromising between desired traits and possible undesired side effects. Often encountered examples include...
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Mycotoxins and Their Producers: Diversity, Side Effects and Control
Mycotoxins are highly toxic compounds, which produced by mycotoxigenic fungi and contaminate foodstuffs resulting in many deleterious effects on...
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Zinc Oxide Nanoparticles and Cancer Chemotherapy: Helpful Tools for Enhancing Chemo-sensitivity and Reducing Side Effects?
Cancer chemotherapy is still a serious challenge. Chemo-resistance and destructive side effects of chemotherapy drugs are the most critical...
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Assessment of Toxic Side Effects of Canned Cauliflower in a Model Plant Test System
AbstractIn food products from plants of the Brassicaceae family, in addition to the beneficial health macronutrients, numerous phytochemicals and...
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Comprehensive network medicine-based drug repositioning via integration of therapeutic efficacy and side effects
Despite advances in modern medicine that led to improvements in cardiovascular outcomes, cardiovascular disease (CVD) remains the leading cause of...
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The insecticides thiamethoxam and chlorantraniliprole do not have side effects on the midgut of the predator Chrysoperla externa (Neuroptera: Chrysopidae)
Chrysoperla externa (Hagen) (Neuroptera: Chrysopidae) is a predator of phytophagous pests in crops; however, this natural enemy may be exposed to...
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Are statins making older persons weaker? A discontinuation study of muscular side effects
Thirteen percent of the Danish population are treated with a statin—half of these are in primary prevention, and most are > 65 years old. Statins...
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Using the Method of Molecular Modeling and Docking to Estimate the Potential Danger of Side Effects of Therapeutic Agents Used with Cardiac Amyloidosis
AbstractCardiac amyloidosis is a clinical pathology (usually of hereditary nature) initiated by the formation of amyloid fibrils, which has a high...
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The left–right side-specific endocrine signaling in the effects of brain lesions: questioning of the neurological dogma
Each cerebral hemisphere is functionally connected to the contralateral side of the body through the decussating neural tracts. The crossed neural...
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Implications of the WTO and EU fuel taxation reforms for a European fishing fleet: effects, side-effects and alternative approaches from an input–output analysis of the Galician (northwest Spain) fleet
The World Trade Organization (WTO) and European Union (EU) have both put forward tax reforms that impact fisheries’ fuel costs, which are similar in...
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Analysis of Isotretinoin-Induced Alterations in the Levels of Plasma Trace Elements: Investigation of the Relationship Between Magnesium, Phosphorus, Potassium, Zinc, and Treatment-Related Side Effects
Isotretinoin is an effective treatment against acne vulgaris, but it also causes many side effects during and after the treatment. The relationship...
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HMMF: a hybrid multi-modal fusion framework for predicting drug side effect frequencies
BackgroundThe identification of drug side effects plays a critical role in drug repositioning and drug screening. While clinical experiments yield...
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Detection of polypharmacy side effects by integrating multiple data sources and convolutional neural networks
AbstractThe consumption of drug combinations, named polypharmacy, is commonly used for treating patients with several diseases or those with complex...
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Enhanced effects of ferulic acid against the harmful side effects of chemotherapy in colon cancer: docking and in vivo study
BackgroundColorectal cancer is considered a potential causative agent of morbidity and death, making it a particularly dangerous malignancy. The...
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A neural network-based method for polypharmacy side effects prediction
BackgroundPolypharmacy is a type of treatment that involves the concurrent use of multiple medications. Drugs may interact when they are used...
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Inhibiting Hv1 channel in peripheral sensory neurons attenuates chronic inflammatory pain and opioid side effects
Both opioids and nonsteroidal anti-inflammatory drugs (NSAIDS) produce deleterious side effects and fail to provide sustained relief in patients with...
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Variation of antlers in individual red deer (Cervus elaphus) stags: repeatability, age and side effects
Antlers are formed anew each year to realise an optimal relationship between their size and weight and the physical body condition in Cervidae . This...
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Intestinal microbiota influences clinical outcome and side effects of early breast cancer treatment
The prognosis of early breast cancer (BC) relies on cell autonomous and immune parameters. The impact of the intestinal microbiome on clinical...
