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Short-chain fatty acids in diseases
Short-chain fatty acids (SCFAs) are the main metabolites produced by bacterial fermentation of dietary fibre in the gastrointestinal tract. The...
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Short-chain fatty acids as a link between diet and cardiometabolic risk: a narrative review
AimDiet has a profound impact on cardiometabolic health outcomes such as obesity, blood glucose, blood lipids and blood pressure. In recent years,...
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Changes of gut microbiota and short chain fatty acids in patients with Peutz–Jeghers syndrome
Peutz–Jeghers Syndromeis a rare autosomal dominant genetic disease characterized by gastrointestinal hamartomatous polyps and skin and mucous...
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Role of Tryptophan Metabolites and Short-Chain Fatty Acids in Pathogenesis of Autoimmune Diseases
AbstractThe prevalence of autoimmune diseases is steadily increasing worldwide. The etiology and pathogenesis of these diseases are extremely complex...
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Short-chain fatty acids: possible regulators of insulin secretion
The benefits of gut microbiota-derived short-chain fatty acids (SCFAs) towards health and metabolism have been emerging since the past decade....
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Predictable Representation of Metabolic Synthesis Pathways of Vitamins and Short-Chain Fatty Acids in Obese Adults
AbstractGut microbiota and its metabolites, such as short-chain fatty acids (SCFAs) and vitamins, are involved in maintaining energy...
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Short-chain fatty acids suppresses astrocyte activation by amplifying Trp-AhR-AQP4 signaling in experimental autoimmune encephalomyelitis mice
The function of astrocytes in response to gut microbiota-derived signals has an important role in the pathophysiological processes of central nervous...
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Spinal cord injury-induced gut dysbiosis influences neurological recovery partly through short-chain fatty acids
Spinal cord injury (SCI) can reshape gut microbial composition, significantly affecting clinical outcomes in SCI patients. However, mechanisms...
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Regulatory role of short-chain fatty acids in inflammatory bowel disease
Inflammatory bowel disease (IBD) comprises a group of chronic inflammatory disorders of the gastrointestinal tract. Accumulating evidence shows that...
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Supplementing the early diet of broilers with soy protein concentrate can improve intestinal development and enhance short-chain fatty acid-producing microbes and short-chain fatty acids, especially butyric acid
BackgroundResearch on nutrition in early-life commonly focuses on the maturation of the intestine because the intestinal system is crucial for...
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Short-chain fatty acids (SCFAs) as potential resuscitation factors that promote the isolation and culture of uncultured bacteria in marine sediments
Many marine bacteria are difficult to culture because they are dormant, rare or found in low-abundances. Enrichment culturing has been widely tested...
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Role of folic acid in regulating gut microbiota and short-chain fatty acids based on an in vitro fermentation model
AbstractFolic acid deficiency is common worldwide and is linked to an imbalance in gut microbiota. However, based on model animals used to study the...
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Microbiota-derived short chain fatty acids in fermented Kidachi Aloe promote antimicrobial, anticancer, and immunomodulatory activities
BackgroundFermented Aloe leaf juice is a commonly used food supplement in Japan. In a previous study, fermentation of A. arborescence juice was...
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Growth performance, caecal microbiome profile, short-chain fatty acids, and litter characteristics in response to placement on reused litter and combined threonine, arginine and glutamine supplementation to juvenile male broiler chickens
BackgroundExposure of broilers to litter microbiome may increase specific amino acid (AA) requirements towards activated immune responses. This may...
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The role of short-chain fatty acids in central nervous system diseases
Previous studies have found that intracorporal short-chain fatty acids (SCFAs), as the main metabolites of the gut microbiota, play important roles...
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Liver sinusoidal endothelial cells rely on oxidative phosphorylation but avoid processing long-chain fatty acids in their mitochondria
BackgroundIt is generally accepted that endothelial cells (ECs), primarily rely on glycolysis for ATP production, despite having functional...
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Revealing the effect of sea buckthorn oil, fish oil and structured lipid on intestinal microbiota, colonic short chain fatty acid composition and serum lipid profiles in vivo
In this study, the effects of sea buckthorn oil (SBO), fish oil (FO) and an enzymatically synthesized structured lipid (SL) on serum, short-chain...
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Impact of short chain fatty acids (SCFAs) on antimicrobial activity of new β-lactam/β-lactamase inhibitor combinations and on virulence of Escherichia coli isolates
AbstractIn a healthy gut microbiota, short chain fatty acids (SCFAs) are produced. The antibacterial action of SCFAs against intestinal pathogens...
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Fatty Acids—‘Fueling Versus Steering’
After a brief description of basic features of fatty acids (FAs), this chapter summarizes recent findings of FAs in terms of sensing, uptake, and... -
Long-chain polyunsaturated fatty acids influence colorectal cancer progression via the interactions between the intestinal microflora and the macrophages
The metabolism of long-chain polyunsaturated fatty acids (LCPUFAs) is closely associated with the risk and progression of colorectal cancer (CRC)....