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Highly sex specific gene expression in Jojoba
BackgroundDioecious plants have male and female flowers on separate plants. Jojoba is a dioecious plant that is drought-tolerant and native to arid...
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Mice lacking DIO3 exhibit sex-specific alterations in circadian patterns of corticosterone and gene expression in metabolic tissues
Disruption of circadian rhythms is associated with neurological, endocrine and metabolic pathologies. We have recently shown that mice lacking...
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Epigenetic Control of Gene Expression
Genetic mutations lead to inheritable changes in the traits. Alterations in genetic features may also be caused by chromatin modifications without...
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Sex-specific expression of pheromones and other signals in gravid starfish
BackgroundMany echinoderms form seasonal aggregations prior to spawning. In some fecund species, a spawning event can lead to population outbreaks...
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Aging is associated with sex-specific alteration in the expression of genes encoding for neuroestradiol synthesis and signaling proteins in the mouse trigeminal somatosensory input
Pain perception is influenced by sex and aging, with previous studies indicating the involvement of aromatase, the estradiol synthase enzyme, in...
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Sex-specific cardiovascular remodeling leads to a divergent sex-dependent development of heart failure in aged hypertensive rats
IntroductionThe prevalence of heart failure with preserved ejection fraction (HFpEF) is continuously rising and predominantly affects older women...
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Genetic insights: map** sex-specific loci in Siamese cobra (Naja kaouthia) sheds light on the putative sex determining region
The location of female-specific/linked loci identified in Siamese cobra ( Naja kaouthia ) previously has been determined through in silico chromosome...
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Sex-specific alteration in human muscle transcriptome with age
Sarcopenia is a medical condition that progressively develops with age and results in reduced skeletal muscle mass, alteration in muscle composition,...
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Gut dysbacteriosis induces expression differences in the adult head transcriptome of Spodoptera frugiperda in a sex-specific manner
Mounting evidence indicates that the gut microbiota influences the neurodevelopment and behavior of insects through the gut-brain axis. However, it...
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Y chromosome toxicity does not contribute to sex-specific differences in longevity
While sex chromosomes carry sex-determining genes, they also often differ from autosomes in size and composition, consisting mainly of silenced...
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Sex-specific circulating unconventional neutrophils determine immunological outcome of auto-inflammatory Behçet’s uveitis
Neutrophils are the most abundant immune cells that first respond to insults in circulation. Although associative evidence suggests that differences...
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Hypothalamic sex-specific metabolic shift by canagliflozin during aging
The hypothalamus undergoes significant changes with aging and plays crucial roles in age-related metabolic alterations. Sodium-glucose co-transporter...
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The influence of sex-specific factors on biological transformations and health outcomes in aging processes
The aging process demonstrates notable differences between males and females, which are key factors in disease susceptibility and lifespan. The...
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X-chromosome inactivation in human iPSCs provides insight into X-regulated gene expression in autosomes
BackgroundVariation in X chromosome inactivation (XCI) in human-induced pluripotent stem cells (hiPSCs) can impact their ability to model biological...
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Regulation of Gene Expression
The mechanisms of gene expression (i.e. the decoding of genetic information as a blueprint to synthesize proteins with a certain structure and...
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Sex specific regulation of TSPY-Like 2 in the DNA damage response of cancer cells
Females have a lower probability to develop somatic cancers and a better response to chemotherapy than males. However, the reasons for these...
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Stage- and sex-specific transcriptome analyses reveal distinctive sensory gene expression patterns in a butterfly
BackgroundAnimal behavior is largely driven by the information that animals are able to extract and process from their environment. However, the...
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Inhibition of WNT/β-catenin signalling during sex-specific gonadal differentiation is essential for normal human fetal testis development
Sex-specific gonadal differentiation is directed by complex signalling promoting development in either male or female direction, while simultaneously...
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Sex-specific plasticity and the nutritional geometry of insulin-signaling gene expression in Drosophila melanogaster
BackgroundSexual-size dimorphism (SSD) is replete among animals, but while the selective pressures that drive the evolution of SSD have been well...
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Maternal diet disrupts the placenta–brain axis in a sex-specific manner
High maternal weight is associated with detrimental outcomes in offspring, including increased susceptibility to neurological disorders such as...
