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Sequential Modeling
The world’s burgeoning population is a concern to economists, social scientists, and agriculturists seeking to feed the world and ensure food...
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Physiological adaptation and population dynamics of a nitrifying sludge exposed to ampicillin
Antibiotics in wastewater treatment plants can alter the physiological activity and the structure of microbial communities through toxic and...
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Microfluidics for adaptation of microorganisms to stress: design and application
AbstractMicrofluidic systems have fundamentally transformed the realm of adaptive laboratory evolution (ALE) for microorganisms by offering...
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Managing Crop Adaptation to Changing Environment
The pressing trends in climate change that are already noticeable, the likelihood of further climate shifts, and the growing magnitude of potential...
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Humic substances and plant abiotic stress adaptation
BackgroundTraditional agriculture is on the front line of climate change, being most impacted by the increase in the intensity and frequency of...
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A low-input high resolution sequential chromatin immunoprecipitation method captures genome-wide dynamics of bivalent chromatin
BackgroundBivalent chromatin is an exemplar of epigenetic plasticity. This co-occurrence of active-associated H3K4me3 and inactive-associated...
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Modulation of aroma and chemical composition of coffee beans through simultaneous and sequential inoculation of Pichia fermentans and Pediococcus pentosaceus during wet fermentation
The combined inoculation of yeast and lactic acid bacteria (LAB) is a promising approach to enhance microbial metabolism and the quality of fermented...
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Short-term adaptation as a tool to improve bioethanol production using grass press-juice as fermentation medium
AbstractGrass raw materials collected from grasslands cover more than 30% of Europe’s agricultural area. They are considered very attractive for the...
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Sequential drug treatment targeting cell cycle and cell fate regulatory programs blocks non-genetic cancer evolution in acute lymphoblastic leukemia
BackgroundTargeted therapies exploiting vulnerabilities of cancer cells hold promise for improving patient outcome and reducing side-effects of...
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MEK and MCL-1 sequential inhibition synergize to enhance rhabdomyosarcoma treatment
Targeted agents have emerged as promising molecules for cancer treatment, but most of them fail to achieve complete tumor regression or attain...
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Climate Change Adaptation in Industrial Areas for Disaster Resilience
Climate is changing, and effects can be seen across the world. The climatic disturbances triggered due to earth’s heating is putting industrial areas...
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Large DNA fragment knock-in and sequential gene editing in Plasmodium falciparum: a preliminary study using suicide-rescue-based CRISPR/Cas9 system
CRISPR/Cas9 technology applied to Plasmodium falciparum offers the potential to greatly improve gene editing, but such expectations including large...
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Origin, variation, and selection of natural alleles controlling flowering and adaptation in wild and cultivated soybean
Soybean ( Glycine max ) is an economically important crop worldwide, serving as a major source of oil and protein for human consumption and animal...
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Genomic analysis uncovers novel candidate genes related to adaptation to tropical climates and milk production traits in native goats
BackgroundSince domestication, both evolutionary forces and human selection have played crucial roles in producing adaptive and economic traits,...
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Plant Pathogen Mitigation and Adaptation to Climate Change
Climate change has a substantial impact on agricultural production. It is crucial to plan and prepare for potential issues related to agricultural...
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Genome mining and physiological analyses uncover adaptation strategies and biotechnological potential of Virgibacillus dokdonensis T4.6 isolated from high-salt shrimp paste
Virgibacillus spp. stand out as a potent starter culture for accelerating the fermention of fish sauces and shrimp pastes. However, the underlying...
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Signification and Application of Mutator and Antimutator Phenotype-Induced Genetic Variations in Evolutionary Adaptation and Cancer Therapeutics
Mutations present a dichotomy in their implications for cellular processes. They primarily arise from DNA replication errors or damage repair...
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Crop Simulation Models for Climate Change Adaptation in Pearl Millet
Globally, climate change has a negative impact on food security, particularly in develo** nations where a growing population is battling food and...
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Investigation of Simultaneous and Sequential Cooperative Homotropic Inhibitor Binding to the Catalytic Chamber of SARS-CoV-2 RNA-dependent RNA Polymerase (RdRp)
In our previous report, the unique architecture of the catalytic chamber of the SARS-CoV-2 RNA-dependent RNA polymerase (RdRp), which harbours two...
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Mechanisms of mitochondrial respiratory adaptation
Mitochondrial energetic adaptations encompass a plethora of conserved processes that maintain cell and organismal fitness and survival in the...
