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  1. SARS-CoV-2 RNA Genome

    Coding regionsCoding regions of the genome are translated into several non-structural proteins, as well as into the widely studied spike protein,...
    Chapter 2023
  2. Comparative susceptibility of SARS-CoV-2, SARS-CoV, and MERS-CoV across mammals

    Exploring wild reservoirs of pathogenic viruses is critical for their long-term control and for predicting future pandemic scenarios. Here, a...

    Meng Li, Juan Du, ... Xuming Zhou in The ISME Journal
    Article Open access 23 January 2023
  3. Antigenic Cartography of SARS-CoV-2

    Abstract

    Antigenic cartography is a tool for interpreting and visualizing antigenic differences between virus variants based on virus neutralization...

    Ekaterina A. Astakhova, Alexey A. Morozov, ... Alexander V. Filatov in Biochemistry (Moscow)
    Article 31 May 2024
  4. Immunology of SARS-CoV-2 Infection

    Abstract

    According to the data from the World Health Organization, about 800 million of the world population had contracted coronavirus infection...

    Aida G. Gabdoulkhakova, Rimma N. Mingaleeva, ... Regina R. Miftakhova in Biochemistry (Moscow)
    Article 01 January 2024
  5. Genetic analysis of ACE2 peptidase domain in SARS-CoV-2-positive and SARS-CoV-2-negative individuals from Pakistan

    Background

    The outbreak of coronavirus disease 2019 (COVID-19) has emerged as a serious public health emergency of global concern. Angiotensin...

    Noor Muhammad, Humaira Naeemi, ... Muhammad Usman Rashid in Molecular Biology Reports
    Article 15 March 2023
  6. Characterization of the Ubiquitin and ISG15 Deconjugase Activity of SARS-CoV-1 and SARS-CoV-2 Papain-Like Protease

    Both severe acute respiratory syndrome coronavirus 1 and 2 (SARS-CoV-1 and SARS-CoV-2) encode a papain-like protease (PLpro), which plays a vital...
    Digant Nayak, Priscila dos Santos Bury, ... Shaun K. Olsen in Deubiquitinases
    Protocol 2023
  7. SARS-CoV-2 biology and host interactions

    The zoonotic emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the ensuing coronavirus disease 2019 (COVID-19) pandemic...

    Silvio Steiner, Annika Kratzel, ... Volker Thiel in Nature Reviews Microbiology
    Article 15 January 2024
  8. Persistence of SARS-CoV-2 Antibodies for a Year Following SARS-CoV-2 Vaccinations (BBV152 and ChAdOx1 nCoV-19)

    The first two vaccines administered in the COVID-19 vaccination campaign of India were Covaxin (BBV152) and Covishield (ChAdOx1-nCoV-19). In this...

    Tanima Dwivedi, Apurva Raj, ... Randeep Guleria in Indian Journal of Clinical Biochemistry
    Article 07 September 2023
  9. Brain exposure to SARS-CoV-2 virions perturbs synaptic homeostasis

    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with short- and long-term neurological complications. The...

    Emma Partiot, Aurélie Hirschler, ... Raphael Gaudin in Nature Microbiology
    Article 28 March 2024
  10. SARS-CoV-2 and Microbiota

    Today, the globe is dealing with the COVID-19 epidemic, which poses a pandemic danger. This infectious disease is triggered by severe acute...
    Edda Russo, Lavinia Curini, ... Amedeo Amedei in Microbiome in Inflammatory Lung Diseases
    Chapter 2022
  11. The Evolution of SARS-CoV-2

    Species evolve over time and viruses are no exception. Extensive genome sequencing of SARS-CoV-2 throughout the global pandemic has allowed for...
    Chapter 2022
  12. Age-specific nasal epithelial responses to SARS-CoV-2 infection

    Children infected with SARS-CoV-2 rarely progress to respiratory failure. However, the risk of mortality in infected people over 85 years of age...

    Maximillian N. J. Woodall, Ana-Maria Cujba, ... Claire M. Smith in Nature Microbiology
    Article Open access 15 April 2024
  13. SARS-CoV-2 evolution in the Omicron era

    Since SARS-CoV-2 BA.5 (Omicron) emerged and spread in 2022, Omicron lineages have markedly diversified. Here we review the evolutionary trajectories...

    Cornelius Roemer, Daniel J. Sheward, ... Thomas P. Peacock in Nature Microbiology
    Article 16 October 2023
  14. Modeling of SARS-CoV-2 Virus Proteins: Implications on Its Proteome

    COronaVIrus Disease 19 (COVID-19) is a severe acute respiratory syndrome (SARS) caused by a group of beta coronaviruses, SARS-CoV-2. The SARS-CoV-2...
    Manish Sarkar, Soham Saha in Homology Modeling
    Protocol 2023
  15. A Method to Monitor Activity of SARS-CoV-2 Nsp3 from Cells

    SARS-CoV-2 protease Nsp3 is a therapeutic target for develo** anti-SARS-CoV-2 drugs. Nsp3 is a large multi-spanning membrane protein, and its...
    Christopher Rainville, David E. Sterner, Kumar Suresh in Deubiquitinases
    Protocol 2023
  16. The evolution of SARS-CoV-2

    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of deaths and substantial morbidity worldwide. Intense scientific...

    Peter V. Markov, Mahan Ghafari, ... Aris Katzourakis in Nature Reviews Microbiology
    Article 05 April 2023
  17. Generation of quality-controlled SARS-CoV-2 variant stocks

    One of the main challenges in the fight against coronavirus disease 2019 (COVID-19) stems from the ongoing evolution of severe acute respiratory...

    Maren de Vries, Grace O. Ciabattoni, ... Meike Dittmann in Nature Protocols
    Article 13 October 2023
  18. A viral assembly inhibitor blocks SARS-CoV-2 replication in airway epithelial cells

    The ongoing evolution of SARS-CoV-2 to evade vaccines and therapeutics underlines the need for innovative therapies with high genetic barriers to...

    Li Du, Fred Deiter, ... Satish K. Pillai in Communications Biology
    Article Open access 22 April 2024
  19. Conformational flexibility in neutralization of SARS-CoV-2 by naturally elicited anti-SARS-CoV-2 antibodies

    As new variants of SARS-CoV-2 continue to emerge, it is important to assess the cross-neutralizing capabilities of antibodies naturally elicited...

    Ruofan Li, Michael Mor, ... Natalia T. Freund in Communications Biology
    Article Open access 05 August 2022
  20. Large-Scale Culture and Plasmid Preparation Procedure for Low-Yield Bacmids Containing Full-Length SARS-CoV-2 cDNAs

    Reverse genetic methods to manipulate viral genomes are key tools in modern virological experimentation. They allow for the generation of reporter...
    Megha Rohamare, Anil Kumar, Joyce A. Wilson in Intracellular Pathogens
    Protocol 2024
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