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Mutational Bias and Natural Selection Driving the Synonymous Codon Usage of Single-Exon Genes in Rice (Oryza sativa L.)
The relative abundance of single-exon genes (SEGs) in higher plants is perplexing. Uncovering the synonymous codon usage pattern of SEGs will benefit...
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Intraspecific and interspecific variations in the synonymous codon usage in mitochondrial genomes of 8 pleurotus strains
In this study, we investigated the codon bias of twelve mitochondrial core protein coding genes (PCGs) in eight Pleurotus strains, two of which are...
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Relative synonymous codon usage of ORF1ab in SARS-CoV-2 and SARS-CoV
BackgroundCOVID-19, as a novel coronavirus disease caused by new coronavirus SARS-CoV-2, spreads all over the world, and brings harm to human in many...
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SARS-CoV-2 continuously optimizes its codon usage to adapt to human lung environment
Viruses need to utilize the resources from host cells to reproduce themselves. RNA translation rate, which is largely determined by codon usage, is...
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Comparative analysis of codon usage bias in chloroplast genomes of ten medicinal species of Rutaceae
Rutaceae family comprises economically important plants due to their extensive applications in spices, food, oil, medicine, etc. The Rutaceae plants...
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Molecular bases for strong phenotypic effects of single synonymous codon substitutions in the E. coli ccdB toxin gene
BackgroundSingle synonymous codon mutations typically have only minor or no effects on gene function. Here, we estimate the effects on cell growth...
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Analysis of codon usage patterns in 48 Aconitum species
BackgroundThe Aconitum genus is a crucial member of the Ranunculaceae family. There are 350 Aconitum species worldwide, with about 170 species found...
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Compositional Dynamics and Codon Usage Pattern of Myogenin (MyoG) Gene across Different Mammalian Species
AbstractMyoG enin ( MyoG ) is one of the key regulatory factors for controlling the generation of skeletal muscle. Codon usage bias (CUB) as a unique...
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An investigation of codon usage pattern analysis in pancreatitis associated genes
BackgroundPancreatitis is an inflammatory disorder resulting from the autoactivation of trypsinogen in the pancreas. The genetic basis of the disease...
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Codon usage bias analysis of the gene encoding NAD+-dependent DNA ligase protein of Invertebrate iridescent virus 6
The genome of Invertebrate iridescent virus 6 (IIV6) contains a sequence that shows similarity to eubacterial NAD + -dependent DNA ligases. The...
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Codon usage bias analysis of mitochondrial protein-coding genes in 12 species of Candida
The incidence of diseases that are caused by fungal infection is gradually increasing, together with antibiotic abuse and the number of patients with...
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Analysis of chloroplast genome characteristics and codon usage bias in 14 species of Annonaceae
For the study of species evolution, chloroplast gene expression, and transformation, the chloroplast genome is an invaluable resource. Codon usage...
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Codon usage of host-specific P genotypes (VP4) in group A rotavirus
BackgroundGroup A rotavirus (RVA) is a common causative agent of acute gastroenteritis in infants and young children worldwide. RVA P genotypes,...
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Codon usage characterization and phylogenetic analysis of the mitochondrial genome in Hemerocallis citrina
BackgroundHemerocallis citrina Baroni is a traditional vegetable crop widely cultivated in eastern Asia for its high edible, medicinal, and...
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Unconventional secretion of Magnaporthe oryzae effectors in rice cells is regulated by tRNA modification and codon usage control
Microbial pathogens deploy effector proteins to manipulate host cell innate immunity, often using poorly understood unconventional secretion routes....
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Codon usage bias and phylogenetic analysis of chloroplast genome in 36 gracilariaceae species
Gracilariaceae is a group of marine large red algae and main source of agar with important economic and ecological value. The codon usage patterns of...
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Codon usage pattern of the ancestor of green plants revealed through Rhodophyta
Rhodophyta are among the closest known relatives of green plants. Studying the codons of their genomes can help us understand the codon usage pattern...
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Comparative analysis of codon usage patterns in the chloroplast genomes of nine forage legumes
Leguminosae is one of the three largest families of angiosperms after Compositae and Orchidaceae . It is widely distributed and grows in a variety of...
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Translation Comes First: Ancient and Convergent Selection of Codon Usage Bias Across Prokaryotic Genomes
Codon usage is the outcome of different evolutionary processes and can inform us about the conditions in which organisms live and evolve. Here, we...
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Codon usage bias
Codon usage bias is the preferential or non-random use of synonymous codons, a ubiquitous phenomenon observed in bacteria, plants and animals....
