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Delayed Rejection of Xenograft (DRX)
Delayed rejection in organ transplantation is observed in a delayed type of immune rejection within a few hours to days after transplantation [1]....
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Hyper Acute Rejection (HAR)
Hyper acute rejection (HAR) occurs 48 h immediately after transplantation. HAR is caused by cytotoxic antibody against donor’s HLA or ABO antigen....
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Classification of Rejection in Host Recipients in Xenotransplantation
Glycome difference between human and non-human species is the most basic concept as a main barrier of xenotransplantation. Determination of...
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Xenogeneic and Allogenic Cellular Rejection (CR)
In solid organ xenotransplantation, the humoral response of human immunity is a direct barrier due to its Abs binding to non-self-antigens of...
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The transplant rejection response involves neutrophil and macrophage adhesion-mediated trogocytosis and is regulated by NFATc3
The anti-foreign tissue (transplant rejection) response, mediated by the immune system, has been the biggest obstacle to successful organ...
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Blood-Mediated Inflammatory Reaction (IBMIR) and Prevention of IBMIR
In transplantation, function loss of grafts is primarily observed in the early time of transplantation, mainly by two known responses of the instant...
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JAK2 gene knockout inhibits corneal allograft rejection in mice by regulating dendritic cell-induced T cell immune tolerance
Corneal allograft rejection can be seen in some patients after corneal transplantation. The present study intends to investigate whether JAK2 gene...
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Fetal liver CD34+ contain human immune and endothelial progenitors and mediate solid tumor rejection in NOG mice
BackgroundTransplantation of CD34 + hematopoietic stem and progenitor cells (HSPC) into immunodeficient mice is an established method to generate...
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IL-37 overexpression promotes endometrial regenerative cell-mediated inhibition of cardiac allograft rejection
BackgroundEndometrial regenerative cells (ERCs) play an important role in attenuation of acute allograft rejection, while their effects are limited....
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Ultraviolet coloration of avian parasitic egg does not cue egg rejection in the common redstart host
Avian brood parasite hosts can use distinct egg traits to recognize a parasitic egg. Previous studies suggested an important role of eggshell...
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Anxious about rejection, avoidant of neglect: Infant marmosets tune their attachment based on individual caregiver’s parenting style
Children’s secure attachment with their primary caregivers is crucial for physical, cognitive, and emotional maturation. Yet, the causal links...
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MiR-146a regulates regulatory T cells to suppress heart transplant rejection in mice
Regulatory T cells (Tregs), which characteristically express forkhead box protein 3 (Foxp3), are essential for the induction of immune tolerance....
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Gut microbiota alterations associated with antibody-mediated rejection after kidney transplantation
AbstractAntibody-mediated rejection (AMR) has become the major challenge for kidney transplantation, and the efficacy of existing therapies was...
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HO-1/BMMSC perfusion using a normothermic machine perfusion system reduces the acute rejection of DCD liver transplantation by regulating NKT cell co-inhibitory receptors in rats
BackgroundLiver transplantation (LT) is required in many end-stage liver diseases. Donation after cardiac death (DCD) livers are often used, and...
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Engineered off-the-shelf therapeutic T cells resist host immune rejection
Engineered T cells are effective therapies against a range of malignancies, but current approaches rely on autologous T cells, which are difficult...
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Dynamics of evolutionary succession and coordination between opposite adaptations in cuckoo hosts under antagonistic coevolution
Adaptations are driven by specific natural selection pressures throughout biological evolution. However, these cannot inherently align with future...
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Polynomial superlevel set representation of the multistationarity region of chemical reaction networks
In this paper we introduce a new representation for the multistationarity region of a reaction network, using polynomial superlevel sets. The...
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Activity-based protein profiling guided identification of urine proteinase 3 activity in subclinical rejection after renal transplantation
BackgroundThe pathophysiology of subclinical versus clinical rejection remains incompletely understood given their equivalent histological severity...
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Intragraft immune cells: accomplices or antagonists of recipient-derived macrophages in allograft fibrosis?
Organ fibrosis caused by chronic allograft rejection is a major concern in the field of transplantation. Macrophage-to-myofibroblast transition plays...
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Does experimentally simulated presence of a common cuckoo (Cuculus canorus) affect egg rejection and breeding success in the red-backed shrike (Lanius collurio)?
Providing artificial eggs is a commonly used technique to understand brood parasitism, mainly by the common cuckoo ( Cuculus canorus ). However, the...
