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Genomic sequencing revealed recombination event between clade 1 and clade 2 occurs in circulating varicella-zoster virus in China
Varicella-zoster virus (VZV), a member of the Alphaherpesvirinae subfamily, causes varicella in primary infections and establishing a latent stage in...
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Single-cell multi-omics sequencing of human spermatogenesis reveals a DNA demethylation event associated with male meiotic recombination
Human spermatogenesis is a highly ordered process; however, the roles of DNA methylation and chromatin accessibility in this process remain largely...
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Efficient targeted recombination with CRISPR/Cas9 in hybrids of Caenorhabditis nematodes with suppressed recombination
BackgroundHomology-based recombination (HR) is the cornerstone of genetic map**. However, a lack of sufficient sequence homology or the presence of...
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Molecular mechanisms and regulation of recombination frequency and distribution in plants
Key messageRecent developments in understanding the distribution and distinctive features of recombination hotspots are reviewed and approaches are...
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Meiotic Recombination
The main outcome of this chapter is to extend the forward simulation program FORTUNA to include crossing-over within a simulated sequence. We begin...
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Analyses of the genetic variation and recombination of CymMV Guangdong isolates
Cymbidium mosaic virus (CymMV) is one of the most important viruses causing economic losses in orchids. The complete genomic sequences of three CymMV...
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Fast and efficient generation of a full-length balancer chromosome by a single Cre/loxP recombination event
Balancer chromosomes, primarily discovered and used in Drosophila melanogaster , are valuable tools to maintain lethal mutations in a particular...
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Fine-scale contemporary recombination variation and its fitness consequences in adaptively diverging stickleback fish
Despite deep evolutionary conservation, recombination rates vary greatly across the genome and among individuals, sexes and populations. Yet the...
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Consequences of Genetic Recombination on Protein Folding Stability
Genetic recombination is a common evolutionary mechanism that produces molecular diversity. However, its consequences on protein folding stability...
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RecView: an interactive R application for locating recombination positions using pedigree data
BackgroundRecombination reshuffles alleles at linked loci, allowing genes to evolve independently and consequently enhancing the efficiency of...
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Constructing founder sets under allelic and non-allelic homologous recombination
Homologous recombination between the maternal and paternal copies of a chromosome is a key mechanism for human inheritance and shapes population...
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Cases of paternal inheritance and recombination of mitochondrial DNA in peas (Pisum L.)
Pea has been hitherto considered to have strict maternal inheritance of mitochondria, as most of flowering plants. Using a CAPS marker we detected a...
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Why do plants need the ZMM crossover pathway? A snapshot of meiotic recombination from the perspective of interhomolog polymorphism
At the heart of meiosis is crossover recombination, i.e., reciprocal exchange of chromosome fragments between parental genomes. Surprisingly, in most...
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Combined Use of Unidirectional Site-Specific Recombination System and CRISPR-Cas Systems for Plant Genome Editing
Site-specific recombination (SSR) systems have been extensively used for controlled genome modification in eukaryotic cells, especially for DNA...
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Physical map** of the wheat genes in low-recombination regions: radiation hybrid map** of the C-locus
Key MessageThis work reports the physical map** of an important gene affecting spike compactness located in a low-recombination region of hexaploid...
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Map** crossover events of mouse meiotic recombination by restriction fragment ligation-based Refresh-seq
Single-cell whole-genome sequencing methods have undergone great improvements over the past decade. However, allele dropout, which means the...
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Chromosome fusions repatterned recombination rate and facilitated reproductive isolation during Pristionchus nematode speciation
Large-scale genome-structural evolution is common in various organisms. Recent developments in speciation genomics revealed the importance of...
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Mosaic Recombination Inflicted Various SARS-CoV-2 Lineages to Emerge into Novel Virus Variants: a Review Update
Human Coronaviruses (hCoVs) belongs to the enormous and dissimilar family of positive-sense, non-segmented, single-stranded RNA viruses. The RNA...
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Recombination map** of the Brazilian stingless bee Frieseomelitta varia confirms high recombination rates in social hymenoptera
BackgroundMeiotic recombination is a fundamental genetic process that shuffles allele combinations and promotes accurate segregation of chromosomes....
