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  1. Optimized Deep Learning for Potato Blight Detection Using the Waterwheel Plant Algorithm and Sine Cosine Algorithm

    Potato blight, sometimes referred to as late blight, is a deadly disease that affects Solanaceae plants, including potato. The oomycete  Phytophthora...

    Ahmed M. Elshewey, Sayed M. Tawfeek, ... Amira Hassan Abed in Potato Research
    Article Open access 28 May 2024
  2. Moving average and standard deviation thresholding (MAST): a novel algorithm for accurate R-wave detection in the murine electrocardiogram

    Advances in implantable radio-telemetry or diverse biologging devices capable of acquiring high-resolution ambulatory electrocardiogram (ECG) or...

    Nicolle J. Domnik, Sami Torbey, ... Damian P. Redfearn in Journal of Comparative Physiology B
    Article 25 July 2021
  3. Dynamic SARS-CoV-2 emergence algorithm for rationally-designed logical next-generation vaccines

    SARS-CoV-2 worldwide spread and evolution has resulted in variants containing mutations resulting in immune evasive epitopes that decrease vaccine...

    David P. Maison, Lauren L. Ching, ... Vivek R. Nerurkar in Communications Biology
    Article Open access 10 October 2022
  4. A functional gene module identification algorithm in gene expression data based on genetic algorithm and gene ontology

    Since genes do not function individually, the gene module is considered an important tool for interpreting gene expression profiles. In order to...

    Yan Zhang, Weiyu Shi, Yeqing Sun in BMC Genomics
    Article Open access 17 February 2023
  5. An Allee-based distributed algorithm for microbial whole-cell sensors

    Reliable detection of substances present at potentially low concentrations is a problem common to many biomedical applications. Complementary to...

    Fabricio Cravo, Matthias Függer, Thomas Nowak in npj Systems Biology and Applications
    Article Open access 22 April 2024
  6. MSXFGP: combining improved sparrow search algorithm with XGBoost for enhanced genomic prediction

    Background

    With the significant reduction in the cost of high-throughput sequencing technology, genomic selection technology has been rapidly...

    Ganghui Zhou, **g Gao, ... Rui Li in BMC Bioinformatics
    Article Open access 11 October 2023
  7. Response Surface Modeling and Multi-objective Genetic Algorithm Optimization of Polyphenol/terpineol Yield from Luffa cylindrica Oil

    Using the Response surface methodology (RSM) and multi-objective genetic algorithm (MOGA) techniques, this study investigated the optimal extraction...

    Kenechi Nwosu-Obieogu, Goziya W. Dzarma, ... Chinonso Udemgba in Proceedings of the National Academy of Sciences, India Section B: Biological Sciences
    Article 14 June 2024
  8. The MultiFurcating Neighbor-Joining Algorithm for Reconstructing Polytomic Phylogenetic Trees

    Results from phylogenetic analyses that study the evolution of species according to their biological characteristics are frequently structured as...

    Alberto Fernández, Natàlia Segura-Alabart, Francesc Serratosa in Journal of Molecular Evolution
    Article Open access 21 October 2023
  9. Comprehensive Guideline for Microbiome Analysis Using R

    The need for a comprehensive consolidated guide for R packages and tools that are used in microbiome data analysis is significant; thus, we aim to...
    Joseph Boctor, Mariam Oweda, Mohamed El-Hadidi in Metagenomic Data Analysis
    Protocol 2023
  10. Wood defect detection based on the CWB-YOLOv8 algorithm

    As an important renewable resource, wood is widely used in various industries. When addressing wood defects that limit the amount of wood used during...

    Hao An, Zhihong Liang, ... Guojian Zeng in Journal of Wood Science
    Article Open access 03 June 2024
  11. Scellpam: an R package/C++ library to perform parallel partitioning around medoids on scRNAseq data sets

    Background

    Partitioning around medoids (PAM) is one of the most widely used and successful clustering method in many fields. One of its key...

    Juan Domingo, Teresa Leon, Esther Dura in BMC Bioinformatics
    Article Open access 14 September 2023
  12. Maintenance of R-loop structures by phosphorylated hTERT preserves genome integrity

    As aberrant accumulation of RNA–DNA hybrids (R-loops) causes DNA damage and genome instability, cells express regulators of R-loop structures. Here...

    Mitsuhiro Machitani, Akira Nomura, ... Kenkichi Masutomi in Nature Cell Biology
    Article 28 May 2024
  13. Inferring cellular and molecular processes in single-cell data with non-negative matrix factorization using Python, R and GenePattern Notebook implementations of CoGAPS

    Non-negative matrix factorization (NMF) is an unsupervised learning method well suited to high-throughput biology. However, inferring biological...

    Jeanette A. I. Johnson, Ashley P. Tsang, ... Genevieve L. Stein-O’Brien in Nature Protocols
    Article 21 November 2023
  14. A topology-marginal composite likelihood via a generalized phylogenetic pruning algorithm

    Bayesian phylogenetics is a computationally challenging inferential problem. Classical methods are based on random-walk Markov chain Monte Carlo...

    Seong-Hwan Jun, Hassan Nasif, ... Frederick A Matsen IV in Algorithms for Molecular Biology
    Article Open access 31 July 2023
  15. ShinyCore: An R/Shiny program for establishing core collection based on single nucleotide polymorphism data

    Background

    Managing and investigating all available genetic resources are challenging. As an alternative, breeders and researchers use core...

    Steven Kim, Dong Sub Kim, ... Seong Heo in Plant Methods
    Article Open access 11 October 2023
  16. CAOS-R: Character-Based Barcoding

    CAOS-Barcoding is a culmination of traditional taxonomy and modern DNA barcoding. CAOS identifies taxa by diagnostic characters as is done in...
    Tjard Bergmann in DNA Barcoding
    Protocol 2024
  17. gcplyr: an R package for microbial growth curve data analysis

    Background

    Characterization of microbial growth is of both fundamental and applied interest. Modern platforms can automate collection of...

    Michael Blazanin in BMC Bioinformatics
    Article Open access 09 July 2024
  18. kalis: a modern implementation of the Li & Stephens model for local ancestry inference in R

    Background

    Approximating the recent phylogeny of N phased haplotypes at a set of variants along the genome is a core problem in modern population...

    Louis J. M. Aslett, Ryan R. Christ in BMC Bioinformatics
    Article Open access 28 February 2024
  19. estimateR: an R package to estimate and monitor the effective reproductive number

    Jérémie Scire, Jana S. Huisman, ... Tanja Stadler in BMC Bioinformatics
    Article Open access 11 August 2023
  20. Real-time cucurbit fruit detection in greenhouse using improved YOLO series algorithm

    The real-time cucurbit fruit detection algorithm in complex environment of greenhouse is associated with challenges. Leaves occlusion, overlap**...

    Olarewaju Mubashiru Lawal in Precision Agriculture
    Article 19 September 2023
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