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Modulation of Quiescent Center Genes by 24-Epibrassinolide Restores Root Phenotype and Cell Wall Architecture in Arsenate-Stressed Rice Seedlings
Arsenic, a toxic contaminant found in agricultural fields, is known to affect crop yield negatively and is taken up by plants via the phosphate...
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Elevated stress response marks deeply quiescent reserve cells of gastric chief cells
Gastrointestinal tract organs harbor reserve cells, which are endowed with cellular plasticity and regenerate functional units in response to tissue...
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Mechanical compression creates a quiescent muscle stem cell niche
Tissue stem cell niches are regulated by their mechanical environment, notably the extracellular matrix (ECM). Skeletal muscles consist of bundled...
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Defective Quiescent Center/AtTRS85 Encoding a TRAPPIII-specific Subunit Required for the Trans-golgi Network/Early Endosome Integrity is Essential for the Proper Root Development in Arabidopsis
Tethering factors mediate the initial contact between donor and acceptor membranes. Transport protein particle (TRAPP)III, a multisubunit tethering...
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Preserving root stem cell functionality under low oxygen stress: the role of nitric oxide and phytoglobins
Main conclusionThe preservation of quiescent center stem cell integrity in hypoxic roots by phytoglobins is exercised through their ability to...
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Coccidioidomycosis and COVID-19 Infection. An Analysis from a Single Medical Center Within the Coccidioidal Endemic Area
At a single medical center, we identified 60 cases of coccidioidomycosis that were coincident with COVID-19 infection. Among these, seven patients...
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Chromatin accessibility dynamics of neurogenic niche cells reveal defects in neural stem cell adhesion and migration during aging
The regenerative potential of brain stem cell niches deteriorates during aging. Yet the mechanisms underlying this decline are largely unknown. Here...
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The primary cilium dampens proliferative signaling and represses a G2/M transcriptional network in quiescent myoblasts
BackgroundReversible cell cycle arrest (quiescence/G0) is characteristic of adult stem cells and is actively controlled at multiple levels. Quiescent...
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Retinoic acid and RARγ maintain satellite cell quiescence through regulation of translation initiation
In adult skeletal muscle, satellite cells are in a quiescent state, which is essential for the future activation of muscle homeostasis and...
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Enhancing prime editing in hematopoietic stem and progenitor cells by modulating nucleotide metabolism
Therapeutic prime editing of hematopoietic stem and progenitor cells (HSPCs) holds great potential to remedy blood disorders. Quiescent cells have...
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Novel whole-mount FISH analysis for intact root of Arabidopsis thaliana with spatial reference to 3D visualization
Whole-mount fluorescent in situ hybridization (WM-FISH) is an effective tool to observe chromosome behavior in tissues or organs. However, it is...
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The role of Notch signaling in endometrial mesenchymal stromal/stem-like cells maintenance
Human endometrium undergoes cycles of regeneration in women of reproductive age. The endometrial mesenchymal stromal/stem cells (eMSC) contribute to...
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Characterization of EGFR-reprogrammable temozolomide-resistant cells in a model of glioblastoma
Temozolomide (TMZ) resistance is a major clinical challenge for glioblastoma (GBM). O 6 -methylguanine-DNA methyltransferase (MGMT) mediated DNA damage...
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Exercise rejuvenates quiescent skeletal muscle stem cells in old mice through restoration of Cyclin D1
Ageing impairs tissue repair. This defect is pronounced in skeletal muscle, whose regeneration by muscle stem cells (MuSCs) is robust in young-adult...
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UCHL1 facilitates protein aggregates clearance to enhance neural stem cell activation in spinal cord injury
Activation of endogenous neural stem cells (NSCs) is greatly significant for the adult neurogenesis; however, it is extremely limited in the spinal...
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On Matrix Stability and Ecological Models
The aim of this chapter is to survey a variety of concepts and results from matrix stability that are relevant to applications in mathematical...
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The inhibition of maize (Zea mays L.) root stem cell regeneration by low oxygen is attenuated by Phytoglobin 1 (Pgb1) through changes in auxin and jasmonic acid
Main conclusionsOver-expression of Phytoglobin1 increases the viability of maize root stem cells to low oxygen stress through changes in auxin and...
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Transitional circulation patterns from full ice cover to ice-off in a seasonally ice-covered lake
There is consensus that under-ice circulation presents multiple phases through the winter, and that different mechanisms dominate each period. In...
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Arabidopsis AtPRP17 functions in embryo development by regulating embryonic patterning
Main conclusionArabidopsis AtPRP17 , a homolog of yeast splicing factor gene PRP17 , is expressed in siliques and embryos and functions in embryo...
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Understanding Ferroptosis from a Free Radical Perspective
Membrane disruption caused by iron-dependent phospholipid peroxidation is a distinctive feature of ferroptosis. Lipid peroxides that are produced...