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A CTL − Lys immune function maintains insect metamorphosis by preventing gut bacterial dysbiosis and limiting opportunistic infections
BackgroundGut bacteria are beneficial to the host, many of which must be passed on to host offspring. During metamorphosis, the midgut of...
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Identification of Semiochemical Candidates Involved in Glossina Palpalis Gambiensis Larviposition Site Selection and Behavioural Responses of Adult Gravid Females
Tsetse flies (Diptera: Glossinidae) are the cyclical vectors of human and animal trypanosomes. This viviparous insect develops and produces a single...
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Stop codon readthrough alters the activity of a POU/Oct transcription factor during Drosophila development
BackgroundA number of cellular processes have evolved in metazoans that increase the proteome repertoire in relation to the genome, such as...
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Environmental Adaptation and Evolution of Circadian Clocks
In insects, circadian clocks regulate daily rhythmicity in behavior (e.g., activity, feeding, mating, and oviposition), physiological processes, and...
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RNA-seq analysis of gene expression changes during pupariation in Bactrocera dorsalis (Hendel) (Diptera: Tephritidae)
BackgroundThe oriental fruit fly, Bactrocera dorsalis (Hendel) has been considered to be one of the most important agricultural pest around the...
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A bacteria-regulated gut peptide determines host dependence on specific bacteria to support host juvenile development and survival
BackgroundCommensal microorganisms have a significant impact on the physiology of host animals, including Drosophila . Lactobacillus and Acetobacter ,...
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Toxicity and insect growth regulatory activities of medicinal plant, Withania somnifera, in flesh fly, Sarcophaga ruficornis (Diptera: Sarcophagidae)
BackgroundThe flesh fly Sarcophaga ruficornis is well known for its medical and veterinary importance in causing myiasis in humans and animals. The...
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Rab26 controls secretory granule maturation and breakdown in Drosophila
At the onset of Drosophila metamorphosis, plenty of secretory glue granules are released from salivary gland cells and the glue is deposited on the...
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Hedgehog pathway is negatively regulated during the development of Drosophila melanogaster PheRS-m (Drosophila homologs gene of human FARS2) mutants
Hereditary spastic paraplegia (HSP) is a neurodegeneration disease, one of the reasons is caused by autosomal recessive missense mutation of the...
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Cyp6g2 is the major P450 epoxidase responsible for juvenile hormone biosynthesis in Drosophila melanogaster
BackgroundJuvenile hormones (JH) play crucial role in regulating development and reproduction in insects. The most common form of JH is JH III,...
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SetDB1 and Su(var)3-9 are essential for late stages of larval development of Drosophila melanogaster
Methylation of H3K9 histone residue is a marker of gene silencing in eukaryotes. Three enzymes responsible for adding this modification — G9a,...
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Responses of two Anastrepha species’ immature stages infesting preferential hosts to different temperature exposures
Anastrepha fraterculus (Wiedemann) and A. obliqua (Macquart) are important pests of fruit crops. In Brazil, these species cause damage to fruit...
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Nutritional ecology of predaceous Tetanocera elata larvae and the physiological effects of alternative prey utilisation
Tetanocera elata (Fabricius) (Diptera: Sciomyzidae) is an obligate mesoparasitoid of pestiferous Deroceras spp. slugs in the first and second larval...
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Evolution and development of male-specific leg brushes in Drosophilidae
The origin, diversification, and secondary loss of sexually dimorphic characters are common in animal evolution. In some cases, structurally and...
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Drosophila NSD deletion induces developmental anomalies similar to those seen in Sotos syndrome 1 patients
BackgroundHaploinsufficiency of the human nuclear receptor binding suppressor of variegation 3–9, enhancer of zeste, and trithorax ( SET ) domain 1...
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Ground-covers affect the activity density of ground-dwelling predators and their impact on the Mediterranean fruit fly, Ceratitis capitata
Three developmental stages of the Mediterranean fruit fly, Ceratitis capitata (Wiedemann) (Diptera: Tephritidae), can be found in the soil (late...
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Manipulation and Visualization of Peroxisomes in Drosophila
Drosophila melanogaster is a proven metazoan model to investigate the fundamentals of human genetic diseases including peroxisome-related disorders....
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Akaluc/AkaLumine bioluminescence system enables highly sensitive, non-invasive and temporal monitoring of gene expression in Drosophila
Bioluminescence generated by luciferase and luciferin has been extensively used in biological research. However, detecting signals from deep tissues...
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A developmental checkpoint directs metabolic remodelling as a strategy against starvation in Drosophila
Steroid hormones are crucial regulators of life-stage transitions during development in animals. However, the molecular mechanisms by which...
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High-Resolution Live Imaging of Axonal RNP Granules in Drosophila Pupal Brain Explants
Dynamic and local adjustments of the axonal proteome are observed in response to extracellular cues and achieved via translation of axonally...