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The evolution of the Puf superfamily of proteins across the tree of eukaryotes
BackgroundEukaryotic gene expression is controlled by a number of RNA-binding proteins (RBP), such as the proteins from the Puf (Pumilio and FBF)...
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Functions, mechanisms and regulation of Pumilio/Puf family RNA binding proteins: a comprehensive review
The Pumilio (Pum)/Puf family proteins are ubiquitously present across eukaryotes, including yeast, plants and humans. They generally bind to the 3′...
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Improvement of beauvericin production by Fusarium oxysporum AB2 under solid-state fermentation using an optimised liquid medium and co-cultures
The production of beauvericin (BEA) by Fusarium oxysporum AB2 in liquid medium (SmF) was compared to that on solid medium (SSF) on inert support...
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Phylogenomic analysis of a metagenome-assembled genome indicates a new taxon of an anoxygenic phototroph bacterium in the family Chromatiaceae and the proposal of “Candidatus Thioaporhodococcus” gen. nov
In this study, three metagenome-assembled genomes of a sediment sample were constructed. A Bin1 (JB001) genome was identified as a...
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Gene editing with an oxathiapiprolin resistance selection marker reveals that PuLLP, a loricrin-like protein, is required for oospore development in Pythium ultimum
Oomycetes, such as Pythium species, contain numerous devastating plant pathogens that inflict substantial economic losses worldwide. Although...
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Analysis of the C. elegans Germline Stem Cell Pool
The Caenorhabditis elegans germline is an excellent model for studying the genetic and molecular regulation of stem cell self-renewal and progression... -
Effects of sequence motifs in the yeast 3′ untranslated region determined from massively parallel assays of random sequences
BackgroundThe 3′ untranslated region (UTR) plays critical roles in determining the level of gene expression through effects on activities such as...
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Aequoribacter fuscus gen. nov., sp. nov., a new member of the family Halieaceae, isolated from coastal seawater
A Gram-stain-negative, rod-shaped, obligately aerobic, nonflagellated, and chemoheterotrophic bacterium, designated IMCC3088 T , was isolated from...
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Plant Co-expression Annotation Resource: a web server for identifying targets for genetically modified crop breeding pipelines
The development of genetically modified crops (GM) includes the discovery of candidate genes through bioinformatics analysis using genomics data,...
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Multi-Omics integration can be used to rescue metabolic information for some of the dark region of the Pseudomonas putida proteome
In every omics experiment, genes or their products are identified for which even state of the art tools are unable to assign a function. In the...
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Inter-α-inhibitor Proteins: A Review of Structure and Function
Inter-α-inhibitor-family proteins (IAIP) are a multifaceted group of complex molecules with important roles in mammalian biology. In the past... -
Ecology of aerobic anoxygenic phototrophs on a fine-scale taxonomic resolution in Adriatic Sea unravelled by unsupervised neural network
BackgroundAerobic anoxygenic phototrophs are metabolically highly active, diverse and widespread polyphyletic members of bacterioplankton whose...
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Transcriptome meta-analysis-based identification of hub transcription factors and RNA-binding proteins potentially orchestrating gene regulatory cascades and crosstalk in response to abiotic stresses in Arabidopsis thaliana
Deteriorating climatic conditions and increasing human population necessitate the development of robust plant varieties resistant to harsh...
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Pseudaestuariivita rosea sp. nov., isolated from Acmaea sp., a marine mollusk
A Gram-stain-negative, pink-pigmented, aerobic, non-motile and rod-shaped bacterium, designated as strain H15 T , was isolated from Acmaea sp.,...
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Genetic Interaction, Epistasis, Modifiers
Biological processes in an organism are interconnected and regulated by a network of genes. Therefore, the genetic dissection of their functional... -
Microbial Production of Ellagic Acid
Ellagic acid is a bioactive compound with important biological properties including antioxidant, anti-proliferative, anti-carcinogenic,... -
Structural and functional similarities and differences in nucleolar Pumilio RNA-binding proteins between Arabidopsis and the charophyte Chara corallina
BackgroundPumilio RNA-binding proteins are evolutionarily conserved throughout eukaryotes and are involved in RNA decay, transport, and translation...
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The genetic and biochemical determinants of mRNA degradation rates in mammals
BackgroundDegradation rate is a fundamental aspect of mRNA metabolism, and the factors governing it remain poorly characterized. Understanding the...
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Precision RNA base editing with engineered and endogenous effectors
RNA base editing refers to the rewriting of genetic information within an intact RNA molecule and serves various functions, such as evasion of the...
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Bioprocessing Cassava Bagasse: Part I—Bioproducts and Biochemicals
Cassava is an essential food source to satisfy the demands of a growing population in tropical and subtropical countries. However, the cassava field...