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Moderate protein intake percentage in mice for maintaining metabolic health during approach to old age
Nutritional requirements for maintaining metabolic health may vary with each life stage, such as young, middle, and old age. To investigate the...
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Mining key circRNA-associated-ceRNA networks for milk fat metabolism in cows with varying milk fat percentages
BackgroundCow milk fat is an essential indicator for evaluating and measuring milk quality and cow performance. Growing research has identified the...
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Solvent-Induced Protein Precipitation for Drug Target Discovery
Traditional chemical proteomics approaches for screening drug targets usually require the immobilization/modification of the drug molecules to pull... -
Selection of optimal quantile protein biomarkers based on cell-level immunohistochemistry data
BackgroundProtein biomarkers of cancer progression and response to therapy are increasingly important for improving personalized medicine. Advanced...
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Algal Protein: Future of Sustainable Food
Due to factors including population growth, rising incomes, increased urbanization, and aging populations, the need for protein components is... -
Peptide-Protein Interface Classification Using Convolutional Neural Networks
Peptides are short chains of amino acid residues linked through peptide bonds, whose potential to act as protein inhibitors has contributed to the... -
Eri Silkworm Pupae: An Alternative Source of Protein in Changing Climate
Climate change affects food security by creating a range of inconveniences including loss of crop productivity, reduction in the quality of crops,... -
E6 Tagged Protein Production, Extraction, and Purification from Escherichia coli Lysate
Cervical cancer has been extensively associated with human papillomavirus (HPV) due to the expression of oncoproteins such as E6. This protein can... -
Early Sowing and Soil Scarification Improve Protein and Oil Contents in Soybean Grains Cultivated in Lowlands
Soybean cultivation in lowlands has increased over the years. In this case, further studies on soybean composition based on management practices are...
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Epigenetic regulation of functional candidate genes for milk production traits in dairy sheep subjected to protein restriction in the prepubertal stage
BackgroundAs the prepubertal stage is a crucial point for the proper development of the mammary gland and milk production, this study aims to...
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Molecular Dynamics Simulation to Study Protein Conformation and Ligand Interaction
The field of molecular dynamics (MD) simulations has become indispensable today to studying the conformational flexibility and dynamics of proteins... -
Optimization of a deep mutational scanning workflow to improve quantification of mutation effects on protein–protein interactions
Deep Mutational Scanning (DMS) assays are powerful tools to study sequence-function relationships by measuring the effects of thousands of sequence...
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Protein expression of nucleolar protein 12 in the retina and its implication in protection of retina from UV irradiation damage
Nucleolar protein 12 (NOL12), one of the nucleolar proteins which are primarily expressed in the nucleolus and play key roles in RNA metabolism, cell...
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A monomeric StayGold fluorescent protein
StayGold is an exceptionally bright and stable fluorescent protein that is highly resistant to photobleaching. Despite favorable fluorescence...
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Improvement of plant resistance to geminiviruses via protein de-S-acylation
Geminiviruses are an important group of viruses that infect a variety of plants and result in heavy agricultural losses worldwide. The homologs of C4...
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Protein Distribution Analysis by a High-Precision Prediction System for Membrane Proteins
To determine the proportion of membrane proteins in the whole genome, we developed a membrane protein prediction system, SOSUI. This system used only... -
Expressional vagaries of OsCAMTA genes under differential abiotic stresses supported with protein–protein interaction study and prediction of miRNA target sites
In response to various stressors, the calmodulin-binding transcription activator (CAMTA) can regulate downstream genes involved in calcium (Ca 2+ )/calm...
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Low Rank Approximation Methods for Identifying Impactful Pairwise Protein Mutations
Assessing how an amino acid mutation impacts protein structure and stability provides insights that advance drug design efforts for combating a... -
Sepiolite as an effective supplement for low-protein diets with the constant energy-protein ratio in broilers
The present study aimed to examine the influence of sepiolite on growth performance, meat quality, intestinal health, some blood parameters, and...
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Investigating Epidermal Growth Factor Receptor Trafficking with High-Resolution Enzymatic Protein-Tagging and Transmission Electron Microscopy
Enzymatic ascorbate peroxidase (APEX) tagging allows for high-resolution, three-dimensional protein distribution analyses in cells and tissues. This...