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Analysis of Golgi Protein Acetylation Using In Vitro Assays and Parallel Reaction Monitoring Mass Spectrometry
Acetylation is one of the most abundant post-translational protein modifications that regulates all cellular compartments ranging from chromatin to...
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Lysine acetylation of histone acetyltransferase adaptor protein ADA2 is a mechanism of metabolic control of chromatin modification in plants
Histone acetylation is a predominant active chromatin mark deposited by histone acetyltransferases (HATs) that transfer the acetyl group from acetyl...
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The acetyltransferase BmCBP changes the acetylation modification of BmSP3 and affects its protein expression in silkworm, Bombyx mori
BackgroundProtein acetylation is an important post-translational modification (PTM) that widely exists in organisms. As a reversible PTM, acetylation...
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Mitochondrial impairment, decreased sirtuin activity and protein acetylation in dorsal root ganglia in Friedreich Ataxia models
Friedreich ataxia (FA) is a rare, recessive neuro-cardiodegenerative disease caused by deficiency of the mitochondrial protein frataxin....
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Hemicellulose Biomass Degree of Acetylation (Natural Versus Chemical Acetylation) as a Strategy for Based Packaging Materials
Facing increasing social, environmental, and economic pressure to substitute non-renewable fossil resources with renewable ones, hemicellulose has...
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RGS7 balances acetylation/de-acetylation of p65 to control chemotherapy-dependent cardiac inflammation
Cardiotoxicity remains a major limitation in the clinical utility of anthracycline chemotherapeutics. Regulator of G-protein Signaling 7 (RGS7) and...
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Regulation of epithelial-mesenchymal transition by protein lysine acetylation
The epithelial-mesenchymal transition (EMT) is a vital driver of tumor progression. It is a well-known and complex trans-differentiation process in...
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Human Platelet Lysate as Valid Cell Growth Additive to Assess Protein Acetylation
Experiments with cell cultures are an alternative to animal experiments. One problem, however, is the ethically questionable use of fetal calf serum...
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COX17 acetylation via MOF–KANSL complex promotes mitochondrial integrity and function
Reversible acetylation of mitochondrial proteins is a regulatory mechanism central to adaptive metabolic responses. Yet, how such functionally...
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Hepatic steatosis is associated with dysregulated cholesterol metabolism and altered protein acetylation dynamics in chickens
BackgroundHepatic steatosis is a prevalent manifestation of fatty liver, that has detrimental effect on the health and productivity of laying hens,...
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Modulation of cellular processes by histone and non-histone protein acetylation
Lysine acetylation is a widespread and versatile protein post-translational modification. Lysine acetyltransferases and lysine deacetylases catalyse...
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Acetylproteomics analyses reveal critical features of lysine-ε-acetylation in Arabidopsis and a role of 14-3-3 protein acetylation in alkaline response
Lysine-ε-acetylation (Kac) is a post-translational modification (PTM) that is critical for metabolic regulation and cell signaling in mammals....
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Acetylation modification in the regulation of macroautophagy
Macroautophagy, commonly referred to as autophagy, is an evolutionarily conserved cellular process that plays a crucial role in maintaining cellular...
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The interaction of canonical Wnt/β-catenin signaling with protein lysine acetylation
Canonical Wnt/β-catenin signaling is a complex cell-communication mechanism that has a central role in the progression of various cancers. The...
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Acetylation proteomics and metabolomics analyses reveal the involvement of starch synthase undergoing acetylation modification during UV-B stress resistance in Rhododendron Chrysanthum Pall
BackgroundRhododendron chrysanthum Pall. ( R. chrysanthum ) is a plant that lives in high mountain with strong UV-B radiation, so R. chrysanthum ...
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Live Cell Synthetic Histone Acetylation by Chemical Catalyst
Posttranslational modifications (PTMs) of histonesPosttranslational modifications (PTMs) of histones, such as lysine acetylation and...
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Proteome-wide analyses reveal diverse functions of protein acetylation and succinylation modifications in fast growing stolons of bermudagrass (Cynodon dactylon L.)
BackgroundBermudagrass ( Cynodon dactylon L.) is an important warm-season turfgrass species with well-developed stolons, which lay the foundation for...
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Pat- and Pta-mediated protein acetylation is required for horizontally-acquired virulence gene expression in Salmonella Typhimurium
Salmonella Typhimurium is a Gram-negative facultative pathogen that causes a range of diseases, from mild gastroenteritis to severe systemic...
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The Role of Histone H2B Acetylation Modification in Aluminum-Induced Cognitive Dysfunction
Aluminum (Al) is a low toxic trace element that can accumulate in the nervous system and induce cognitive disorders characterized by reduced learning...
