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  1. Peptidomics Strategies to Evaluate Cancer Diagnosis, Prognosis, and Treatment

    Peptides have potential bioactive functions, and the peptidomics landscape has been broadly investigated for various diseases, including cancer. In...
    Daniella Figueiredo, Rodrigo G. B. Cruz, ... Adriana Franco Paes Leme in Peptidomics
    Protocol 2024
  2. Epigenetics in the Diagnosis, Prognosis, and Therapy of Cancer

    As cancer is the leading cause of death worldwide, there is an urgent necessity to discover novel diagnostic and prognostic biomarkers as well as...
    Leilei Fu, Bo Liu in Cancer Epigenetics
    Chapter 2023
  3. Identification and validation of tumor-infiltrating lymphocyte-related prognosis signature for predicting prognosis and immunotherapeutic response in bladder cancer

    Background

    It has been discovered that tumor-infiltrating lymphocytes (TILs) are essential for the emergence of bladder cancer (BCa). This study aimed...

    Canxuan Li, Weibin **e in BMC Bioinformatics
    Article Open access 27 March 2023
  4. Cuproptosis Regulates Microenvironment and Affects Prognosis in Prostate Cancer

    Current immunotherapy for prostate cancer is still in the stage of clinical trials. This delay is thought to be caused by an unclear regulatory...

    Chao Li, Yongqiang **ao, ... Fengchao Yin in Biological Trace Element Research
    Article 08 May 2023
  5. Novel targets and their functions in the prognosis of uterine corpus endometrial cancer patients

    Aberrant mRNA expression is implicated in uterine corpus endometrial carcinoma (UCEC) oncogenesis and progression. However, effective prognostic...

    **n Sui, Penghui Feng, ... Feng Deng in Journal of Applied Genetics
    Article 19 April 2024
  6. Predictive value of CCL2 in the prognosis and immunotherapy response of glioblastoma multiforme

    Background

    Glioblastoma multiforme (GBM) is the most common and lethal primary brain tumor with a poor prognosis. The C-C motif chemokine ligand 2...

    Longfei Deng, Jie Ren, ... Hongjuan Cui in BMC Genomics
    Article Open access 06 December 2023
  7. High expression of Testin predicted worse prognosis in pancreatic adenocarcinoma associated with immune infiltration

    Background

    Pancreatic adenocarcinoma (PAAD) is a malignant tumor with a very poor prognosis and lacks effective biomarkers. Testin ( TES ) has an...

    Rui Chen, Zhengli Zhou, ... Tao Wang in Molecular & Cellular Toxicology
    Article 30 April 2024
  8. Lipid parameters, adipose tissue distribution and prognosis prediction in chronic kidney Disease patients

    Background

    Lipid management in clinic is critical to the prevention and treatment of Chronic kidney disease (CKD), while the manifestations of lipid...

    Hui-fen Chen, Bing-jie **ao, ... Yi-fan Wu in Lipids in Health and Disease
    Article Open access 08 January 2024
  9. Glycolysis induces Th2 cell infiltration and significantly affects prognosis and immunotherapy response to lung adenocarcinoma

    Glycolysis has a major role in cancer progression and can affect the tumor immune microenvironment, while its specific role in lung adenocarcinoma...

    Li** Zeng, Lu Liang, ... Zhenbo Feng in Functional & Integrative Genomics
    Article 04 July 2023
  10. Featured lncRNA-based signature for discriminating prognosis and progression of hepatocellular carcinoma

    Long non-coding RNAs (lncRNAs) have been implicated in carcinogenesis and progression of hepatocellular carcinoma (HCC). This study aimed to identify...

    Huiyuan Qiu, Bo Jiang, ... **aolei Cao in Journal of Applied Genetics
    Article 12 February 2024
  11. Association of Plasma Selenium and Its Untargeted Metabolomic Profiling with Cervical Cancer Prognosis

    Selenium is an essential trace element that shows beneficial or adverse health effects depending on the dose. However, its role in the prognosis of...

    Lei Qi, Yuanyuan Wang, ... Tong Wang in Biological Trace Element Research
    Article 07 January 2023
  12. Low FHL1 expression indicates a good prognosis and drug sensitivity in ovarian cancer

    Chemotherapy resistance is the main reason for the poor prognosis of ovarian cancer (OC). FHL1 is an important tumour regulator, but its relationship...

    **aoying Chen, Yue Yu, ... Fuqiang Yin in Functional & Integrative Genomics
    Article 07 February 2024
  13. Characterizing the key genes of COVID-19 that regulate tumor immune microenvironment and prognosis in hepatocellular carcinoma

    Hepatocellular carcinoma (HCC), a highly heterogeneous malignant tumor associated with a poor prognosis, is a common cause of cancer-related deaths...

    Shuang Gao, Lei Zhang, Huiyan Wang in Functional & Integrative Genomics
    Article 04 August 2023
  14. Mitochondria-related lncRNAs: predicting prognosis, tumor microenvironment and treatment response in lung adenocarcinoma

    Lung cancer is the most common type of malignant tumor that affects people in China and even across the globe, as it exhibits the highest rates of...

    Qianhui Zhou, Jiali **ong, ... Ying Chen in Functional & Integrative Genomics
    Article Open access 21 October 2023
  15. Endoplasmic reticulum stress-related gene model predicts prognosis and guides therapies in lung adenocarcinoma

    Background

    The prognosis and survival of lung adenocarcinoma (LUAD) patients are still not promising despite recent breakthroughs in treatment....

    Yuqi Song, Jianzun Ma, ... Wei Liu in BMC Bioinformatics
    Article Open access 16 June 2023
  16. A cuproptosis-related lncRNA signature for predicting prognosis and immunotherapy response of lung adenocarcinoma

    Background

    Copper-induced cell death (cuproptosis) is a new regulatory cell death mechanism. Long noncoding RNAs (lncRNAs) are related to tumor...

    Sheng Yu, Lingxue Tang, ... Huaidong Cheng in Hereditas
    Article Open access 24 July 2023
  17. An immunogenic cell death-related gene expression signature in predicting prognosis of pancreatic ductal adenocarcinoma

    Background

    Immunogenic cell death (ICD) has been identified as regulated cell death, which is sufficient to activate the adaptive immune response....

    **aobo Wang, Tianxiang Ren, ... **g Cao in BMC Genomics
    Article Open access 23 February 2024
  18. ULBP2 is a biomarker related to prognosis and immunity in colon cancer

    The study aimed to determine whether ULBP2 was associated with prognosis and immune infiltration in colon cancer (CC) and provided important...

    ** Yang, **aolu Su, ... Dekui Zhang in Molecular and Cellular Biochemistry
    Article 12 January 2023
  19. Development and validation of epigenetic modification-related signals for the diagnosis and prognosis of colorectal cancer

    Background

    Colorectal cancer (CRC) is one of the world's most common malignancies. Epigenetics is the study of heritable changes in characteristics...

    **a Li, **g**g Li, ... Liwei Zhuang in BMC Genomics
    Article Open access 11 January 2024
  20. MicroRNA: Role in Gene Regulation, Disease Prognosis, Radiotherapy, and the Activity of Radioprotectors

    Abstract

    MicroRNAs are small, highly conserved noncoding RNAs (containing about 20 nucleotides), involved in the regulation of gene activity on the...

    D. V. Saleeva, N. F. Raeva, ... G. D. Zasukhina in Biology Bulletin
    Article 01 December 2023
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