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Peptidomics Strategies to Evaluate Cancer Diagnosis, Prognosis, and Treatment
Peptides have potential bioactive functions, and the peptidomics landscape has been broadly investigated for various diseases, including cancer. In... -
Epigenetics in the Diagnosis, Prognosis, and Therapy of Cancer
As cancer is the leading cause of death worldwide, there is an urgent necessity to discover novel diagnostic and prognostic biomarkers as well as... -
Identification and validation of tumor-infiltrating lymphocyte-related prognosis signature for predicting prognosis and immunotherapeutic response in bladder cancer
BackgroundIt has been discovered that tumor-infiltrating lymphocytes (TILs) are essential for the emergence of bladder cancer (BCa). This study aimed...
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Cuproptosis Regulates Microenvironment and Affects Prognosis in Prostate Cancer
Current immunotherapy for prostate cancer is still in the stage of clinical trials. This delay is thought to be caused by an unclear regulatory...
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Novel targets and their functions in the prognosis of uterine corpus endometrial cancer patients
Aberrant mRNA expression is implicated in uterine corpus endometrial carcinoma (UCEC) oncogenesis and progression. However, effective prognostic...
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Predictive value of CCL2 in the prognosis and immunotherapy response of glioblastoma multiforme
BackgroundGlioblastoma multiforme (GBM) is the most common and lethal primary brain tumor with a poor prognosis. The C-C motif chemokine ligand 2...
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High expression of Testin predicted worse prognosis in pancreatic adenocarcinoma associated with immune infiltration
BackgroundPancreatic adenocarcinoma (PAAD) is a malignant tumor with a very poor prognosis and lacks effective biomarkers. Testin ( TES ) has an...
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Lipid parameters, adipose tissue distribution and prognosis prediction in chronic kidney Disease patients
BackgroundLipid management in clinic is critical to the prevention and treatment of Chronic kidney disease (CKD), while the manifestations of lipid...
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Glycolysis induces Th2 cell infiltration and significantly affects prognosis and immunotherapy response to lung adenocarcinoma
Glycolysis has a major role in cancer progression and can affect the tumor immune microenvironment, while its specific role in lung adenocarcinoma...
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Featured lncRNA-based signature for discriminating prognosis and progression of hepatocellular carcinoma
Long non-coding RNAs (lncRNAs) have been implicated in carcinogenesis and progression of hepatocellular carcinoma (HCC). This study aimed to identify...
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Association of Plasma Selenium and Its Untargeted Metabolomic Profiling with Cervical Cancer Prognosis
Selenium is an essential trace element that shows beneficial or adverse health effects depending on the dose. However, its role in the prognosis of...
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Low FHL1 expression indicates a good prognosis and drug sensitivity in ovarian cancer
Chemotherapy resistance is the main reason for the poor prognosis of ovarian cancer (OC). FHL1 is an important tumour regulator, but its relationship...
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Characterizing the key genes of COVID-19 that regulate tumor immune microenvironment and prognosis in hepatocellular carcinoma
Hepatocellular carcinoma (HCC), a highly heterogeneous malignant tumor associated with a poor prognosis, is a common cause of cancer-related deaths...
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Mitochondria-related lncRNAs: predicting prognosis, tumor microenvironment and treatment response in lung adenocarcinoma
Lung cancer is the most common type of malignant tumor that affects people in China and even across the globe, as it exhibits the highest rates of...
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Endoplasmic reticulum stress-related gene model predicts prognosis and guides therapies in lung adenocarcinoma
BackgroundThe prognosis and survival of lung adenocarcinoma (LUAD) patients are still not promising despite recent breakthroughs in treatment....
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A cuproptosis-related lncRNA signature for predicting prognosis and immunotherapy response of lung adenocarcinoma
BackgroundCopper-induced cell death (cuproptosis) is a new regulatory cell death mechanism. Long noncoding RNAs (lncRNAs) are related to tumor...
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An immunogenic cell death-related gene expression signature in predicting prognosis of pancreatic ductal adenocarcinoma
BackgroundImmunogenic cell death (ICD) has been identified as regulated cell death, which is sufficient to activate the adaptive immune response....
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ULBP2 is a biomarker related to prognosis and immunity in colon cancer
The study aimed to determine whether ULBP2 was associated with prognosis and immune infiltration in colon cancer (CC) and provided important...
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Development and validation of epigenetic modification-related signals for the diagnosis and prognosis of colorectal cancer
BackgroundColorectal cancer (CRC) is one of the world's most common malignancies. Epigenetics is the study of heritable changes in characteristics...
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MicroRNA: Role in Gene Regulation, Disease Prognosis, Radiotherapy, and the Activity of Radioprotectors
AbstractMicroRNAs are small, highly conserved noncoding RNAs (containing about 20 nucleotides), involved in the regulation of gene activity on the...