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Metabolomic profiling of preterm birth in pregnant women living with HIV
BackgroundPreterm birth is a leading cause of death in children under the age of five. The risk of preterm birth is increased by maternal HIV...
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Meta-analysis reveals the vaginal microbiome is a better predictor of earlier than later preterm birth
BackgroundHigh-throughput sequencing measurements of the vaginal microbiome have yielded intriguing potential relationships between the vaginal...
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Genetic Testing in Pregnancy to Assess the Risk of Preterm Birth
Preterm birth (PTB) is one of the leading causes of infant and child mortality under 5 years of age. PTB infants have long-term health consequences... -
Preterm birth is associated with xenobiotics and predicted by the vaginal metabolome
Spontaneous preterm birth (sPTB) is a leading cause of maternal and neonatal morbidity and mortality, yet its prevention and early risk...
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Longitudinal development of the airway metagenome of preterm very low birth weight infants during the first two years of life
Preterm birth is accompanied with many complications and requires severe therapeutic regimens at the neonatal intensive care unit. The influence of...
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Prophylactic administration of human amniotic fluid stem cells suppresses inflammation-induced preterm birth via macrophage polarization
Ascending inflammation from the vagina is a major cause of preterm birth. Currently, this condition—especially when uncontrolled—has no effective...
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Changes in preterm birth and stillbirth during COVID-19 lockdowns in 26 countries
Preterm birth (PTB) is the leading cause of infant mortality worldwide. Changes in PTB rates, ranging from −90% to +30%, were reported in many...
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The impact of premature birth on auditory-visual processes in very preterm schoolchildren
Interactions between stimuli from different sensory modalities and their integration are central to daily life, contributing to improved perception....
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PredictPTB: an interpretable preterm birth prediction model using attention-based recurrent neural networks
BackgroundEarly identification of pregnant women at risk for preterm birth (PTB), a major cause of infant mortality and morbidity, has a significant...
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The Influence of Preterm Birth on the Development of Rat Myocardium in the Early Postnatal Period of Ontogenesis
AbstractThe development of neonatology makes it possible to overcome increasingly severe degrees of prematurity. It has been established that the...
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Preterm Breast Milk Composition
There is variation in the composition of milk in different lactation phases. Likewise, the composition differs between individuals as well as in... -
DNA methylation changes in African American women with a history of preterm birth from the InterGEN study
BackgroundPreterm birth (< 37 weeks’ gestation) is a common outcome of pregnancy that has been associated with increased risk of cardiovascular...
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Early gut microbiota in very low and extremely low birth weight preterm infants with feeding intolerance: a prospective case-control study
The potential role of the gut microbiota in the pathogenesis of feeding intolerance (FI) remains unclear. Understanding the role of the gut...
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Detection of Matrix Metalloproteinases in the Heart of Preterm Rats
AbstractThe influence of preterm birth on the expression of matrix metalloproteinases (MMP2 and MMP9) in the wall of the left ventricle of the rat...
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Elevated methylation of the vault RNA2-1 promoter in maternal blood is associated with preterm birth
BackgroundPreterm birth, defined as parturition before 37 completed weeks of gestation, is associated with an increased risk of neonatal...
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An Immunohistochemical Study of Matrix Metalloproteinase 2 and 9 in the Left Ventricle of the Heart of Preterm Born Rats in the Late Period of Ontogenesis
AbstractImmunohistochemical detection of matrix metalloproteinase (MMP) 2 and 9 was carried out in the myocardium of the left ventricle of preterm...
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Vaginal microbiota in women with spontaneous preterm labor versus those with term labor in Kenya: a case control study
BackgroundPreterm birth is a global problem with about 12% of births in sub-Saharan Africa occurring before 37 weeks of gestation. Several studies...
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Detecting Intra Ventricular Haemorrhage in Preterm Neonates Using LSTM Autoencoders
The neonatal period is a critical stage where physiological adaptations for extra-uterine life occur, and newborns are vulnerable to various diseases... -
The Structure of the Left Ventricle Myocardium of Preterm Rats in the Early Postnatal Period
AbstractPreterm birth is positively correlated with a predisposition to the development of diseases of the cardiovascular system in adulthood. The...
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A comparative analyses of lipid ratios representing desaturase enzyme activity between preterm and term infants within the first ten weeks of life
BackgroundDesaturase enzymes play a key role in several pathways including biosynthesis of poly- and mono- unsaturated fatty acids (PUFAs, MUFA). In...