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Can Prenatal or Neonatal Exposure to Chemosensory Variety Orient the Development of Personality? Exploratory Investigations in Mice
Odorant compounds that mammalian females ingest during pregnancy/lactation permeate to their perinatal offspring, im**ing on progeny’s develo**... -
Exercise reduces physical alterations in a rat model of fetal alcohol spectrum disorders
BackgroundPrenatal alcohol exposure (PAE) has serious physical consequences for children such as behavioral disabilities, growth disorders,...
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Telomere length: how the length makes a difference
Telomerase is perceived as an immortality enzyme that might provide longevity to cells and whole organisms. Importantly, it is generally inactive in...
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Updating an Overview of Teratology
In this chapter, the authors aim to update an overview of the principles of teratology, beginning with the definition of teratology, the critical... -
Retinopathy of prematurity: contribution of inflammatory and genetic factors
Retinopathy of prematurity (ROP) is a retinal vasoproliferative disorder that represents an important cause of childhood visual impairment and...
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Cytotoxicity Models in Chromaffin Cells to Evaluate Neuroprotective Compounds
Primary cultures of bovine chromaffin cells are considered a good model to evaluate potential neuroprotective compounds for two major reasons: (i)... -
Development Features on the Selection of Animal Models for Teratogenic Testing
Today, the use of animal models from different species continues to represent a fundamental step in teratogenic testing, despite the increase in... -
The Expression of Recombinant Human Hepatocyte Growth Factor in Pichia pastoris
AbstractThe aim of this study was to construct a stable and efficient eukaryotic expression system for the secretion of biologically active...
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Zebrafish toxicological screening could aid Leishmaniosis drug discovery
BackgroundRecently a screen from a library of 1.8 million compounds identified in vitro a potent activity of the 2-aminobenzimidazoles series against
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Bird embryos perceive vibratory cues of predation risk from clutch mates
During development in fluctuating environments, phenotypes can be adjusted to the conditions that individuals will probably encounter later in life....
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The neuroanatomy of developmental language disorder: a systematic review and meta-analysis
Developmental language disorder (DLD) is a common neurodevelopmental disorder with adverse impacts that continue into adulthood. However, its neural...
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Common Fallow Deer Dama dama (Linnaeus, 1758)
This comprehensive species-specific chapter covers all aspects of the mammalian biology, including paleontology, physiology, genetics, reproduction... -
Synergistic effects of hormones on structural and functional maturation of cardiomyocytes and implications for heart regeneration
The limited endogenous regenerative capacity of the human heart renders cardiovascular diseases a major health threat, thus motivating intense...
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Common Fallow Deer Dama dama (Linnaeus, 1758)
This comprehensive species-specific chapter covers all aspects of the mammalian biology, including paleontology, physiology, genetics, reproduction... -
Bioremediation Strategies to Mitigate the Impact of Atrazine on the Environment: Recent Advances and Prospects
Atrazine is an s-triazine herbicide widely used for the control of weeds, primarily in corn, sorghum and sugarcane crops. It is relatively persistent... -
Fluorescence In Situ Hybridization of Small Non-Coding RNAs
The determination of the cellular localization of a noncoding RNA (ncRNA) is highly helpful to decipher its function. RNA-FISH is a powerful method... -
Geoffroy’s Bat Myotis emarginatus (E. Geoffroy, 1806)
This comprehensive species‑specific chapter covers all aspects of the mammalian biology, including paleontology, physiology, genetics, reproduction... -
Geoffroy’s Bat Myotis emarginatus (Geoffroy, 1806)
This comprehensive species‑specific chapter covers all aspects of the mammalian biology, including paleontology, physiology, genetics, reproduction... -
First ovarian response to gonadotrophin stimulation in rats exposed to neonatal androgen excess
This study analyzes the effects of neonatal androgenization on follicular growth and first ovulation in response to gonadotrophins, using a model of...