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Prenatal Genetic Testing
Screening pregnancies for genetic disorders has become an integral part of antenatal care. Presently, a wide variety of prenatal screening tests in...
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Application of the prenatal BACs-on-Beads™ assay for rapid prenatal detection of sex chromosome mosaicism
The prenatal BACs-on-Beads™ (BoBs) assay was introduced for rapid detection of abnormalities of chromosomes 13, 18, 21, X, and Y and specific nine...
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Prenatal Interventions for the Treatment of Congenital Disorders
Congenital genetic defects are the leading cause of morbidity and mortality. With progress in diagnostic methods, many of these diseases can be...
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Distinct epigenetic modulation of differentially expressed genes in the adult mouse brain following prenatal exposure to low-dose bisphenol A
Bisphenol A (BPA) is a common component in the manufacture of daily plastic consumer goods. Recent studies have suggested that prenatal exposure to...
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Prenatal lipopolysaccharide exposure induces anxiety-like behaviour in male mouse offspring and aberrant glial differentiation of embryonic neural stem cells
BackgroundPrenatal infection has been implicated in the development of neuropsychiatric disorders in children. We hypothesised that exposure to...
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Tracing Slow Phenoptosis to the Prenatal Stage in Social Vertebrates
AbstractVladimir Skulachev’s coining of the term “phenoptosis” 25 years ago (Skulachev, V. P., Biochemistry (Moscow) , 62 , 1997) highlighted the...
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Prenatal Therapy for Congenital Diaphragmatic Hernia and Myelomeningocele: Advances in Particle-Based Delivery
Purpose of ReviewPrenatal intervention for congenital diseases could potentially halt or reverse devastating co-morbidities. Particle-based therapy...
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Prenatal caloric restriction adjusts the energy homeostasis and behavior in response to acute and chronic variations in food availability in adulthood
Fetal metabolic programming produced by unfavorable prenatal nutritional conditions leads to the development of a disorder called “thrifty...
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Prenatal and postnatal development of New Zealand white rabbit (Oryctolagus cuniculus) teeth: histological and computed tomography aspects
The study reveals a lack of histomorphogenesis in New Zealand white rabbit teeth. The teeth development was examined through sequential histological...
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Diagnosis of prenatal 22q11.2 duplication syndrome: a two-case study
The objective of the study was to perform the prenatal diagnosis of two foetuses with 22q11.2 duplication for 2.5 Mb after noninvasive prenatal...
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Transgenerational Effects of Prenatal Stress on Memory and Expression of the Insulin-Like Growth Factor 2 Gene in the Offspring Brain
AbstractPrenatal maternal stress disrupts offspring behavior and cognitive abilities not only in the first but also in subsequent...
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The role of serum-glucocorticoid regulated kinase 1 in reproductive viability: implications from prenatal programming and senescence
ObjectiveOrganisms and cellular viability are of paramount importance to living creatures. Disruption of the balance between cell survival and...
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Resetting histone modifications during human prenatal germline development
Histone modifications play critical roles in regulating gene expression and present dynamic changes during early embryo development. However, how...
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Prenatal ethanol exposure and changes in fetal neuroendocrine metabolic programming
Prenatal ethanol exposure (PEE) (mainly through maternal alcohol consumption) has become widespread. However, studies suggest that it can cause...
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Prenatal Screening and Counseling for Rare Genetic Disorders
Genetic counseling is an important component of healthcare that provides individuals and families affected by rare genetic illnesses with important...
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Docosahexaenoic Acid Effect on Prenatal Exposure to Arsenic and Atopic Dermatitis in Mexican Preschoolers
Childhood atopic dermatitis (AD) is a chronic and recurrent health problem that involves multiple factors, particularly immunological and...
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Prenatal folic acid and vitamin B12 imbalance alter neuronal morphology and synaptic density in the mouse neocortex
Previous reports have provided evidence that insufficient or excessive maternal folic acid (FA) intake during pregnancy can alter neurodevelopment of...
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Prenatal glucocorticoid administration accelerates the maturation of fetal rat hepatocytes
BackgroundPrenatal glucocorticoid (GC) is clinically administered to pregnant women who are at risk of preterm birth for the maturation of...
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Stem Cell-Based Strategies for Prenatal Treatment of Spina Bifida and the Promise of Cell-Free, Minimally Invasive Approaches
Purpose of ReviewSpina bifida (SB) is a severe birth defect that affects 1400 newborns annually in the USA. SB is often diagnosed before irreversible...
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Relationship of Growth Rates to Prenatal Micronutrient Supplementation in Replacement Heifers
AbstractIn accordance with the developmental origins of health and disease (DoHaD) hypotheses, the intrauterine fetal growth environments have a...