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Menopause and the Bridge to Cardiovascular Disease
Before menopause women are protected against cardiovascular disease morbidity and mortality, relative to age-matched men. After menopause...
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Estrogen enforces the integrity of blood vessels in the bone during pregnancy and menopause
The mammalian skeletal system shows sex differences in structure, functions, aging and disease incidences. The role of blood vessels in...
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Tinospora cordifolia as a Potential Candidate for Health Care of Post-Menopausal Women
In women, biological aging is accelerated with reproductive phase cessation which is mainly attributed to the decline in biological reserves of sex...
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Chronological and reproductive aging-associated changes in resistance to oxidative stress in post-reproductive female mice
Effort toward reproduction is often thought to negatively influence health and survival. Reproduction has been shown to influence metabolism, but the...
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Decline in endothelial function across the menopause transition in healthy women is related to decreased estradiol and increased oxidative stress
Endothelial function declines progressively across stages of the menopause transition; however, the mechanisms contributing to this decline are...
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Aging-associated changes in motor function are ovarian somatic tissue-dependent, but germ cell and estradiol independent in post-reproductive female mice exposed to young ovarian tissue
A critical mediator of evolution is natural selection, which operates by the divergent reproductive success of individuals and results in conformity...
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Blood Pressure: Changes Over a Woman’s Life, the Effect of Estrogen, and Special Considerations in Women
Hypertension is an important risk factor for cardiovascular disease in women and is one of the leading contributors to morbidity and mortality in...
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Ovarian aging in humans: potential strategies for extending reproductive lifespan
Ovarian reserve is a term used to estimate the total number of immature follicles present in the ovaries. Between birth and menopause, there is a...
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MicroRNAs regulate the vicious cycle of vascular calcification-osteoporosis in postmenopausal women
Menopause is a normal physiological process accompanied by changes in various physiological states. The incidence of vascular calcification (VC)...
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Effect of Metanil Yellow on Pre-natal and Post-natal Physiology: A Study on Rat Model
Metanil yellow (MY) is a widely used colour additive to impart yellow or orange hues in food items to make it more attractive to consumers. Previous...
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D-limonene supplementation does not alter postprandial metabolism of postmenopausal women challenged with a mixed macronutrient tolerance test: a pilot study
The hormonal decline during menopause increases women's risk of chronic diseases. D-limonene, a monoterpene found in the human diet, possesses...
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Cardiometabolic Function in Women
Metabolic syndrome and associated increased risk of cardiovascular diseases developed the new global concept of cardiometabolic risk. Insulin...
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Unraveling female reproductive senescence to enhance healthy longevity
In a society where women often want successful careers and equal opportunities to men, the early nature of ovarian aging often forces women to make...
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Butyrate mitigates metabolic dysfunctions via the ERα-AMPK pathway in muscle in OVX mice with diet-induced obesity
The higher prevalence of metabolic syndrome (MetS) in women after menopause is associated with a decrease in circulating 17β-oestradiol. To explore...
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Female aging: when translational models don’t translate
For many pathologies associated with aging, female patients present with higher morbidity and more frequent adverse events from treatments compared...
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Role of Estrogen in Attenuating Apoptosis and Cardiac Dysfunction in Female Heart Failure
Cardiovascular diseases including heart failure are the major cause of morbidity and mortality in both males and females of all ages and ethnicities....
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Isoflavone-enriched soybean leaves (Glycine max) restore loss of dermal collagen fibers induced by ovariectomy in the Sprague Dawley rats
Phytoestrogens, such as isoflavones, are known for their capacity to simulate various physiological impacts of estrogen in the human body. Our...
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Heart Ischemia/Reperfusion Injury—Is the Female Equally Protected Compared to Male?
Despite the decrease in cardiovascular mortality over the past 3 decades, it still remains the leading cause of death in women. Young women have a...
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Early detection of breast cancer through the diagnosis of Nipple Aspirate Fluid (NAF)
The development of breast cancer has been mainly reported in women who have reached the post-menopausal stage; therefore, it is the primary factor...
