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Induced Pluripotent Stem Cells
Induced pluripotent stem cells (iPSCs) offer huge promise and potential in the creation of patient-specific stem cells for modeling human diseases,...
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Different Types of Pluripotent Stem Cells Represent Different Developmental Stages
Pluripotent stem cell lines established from early-stage embryos of mammals or other species represent the embryonic stages before the initiation of...
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Induced Pluripotent Stem Cells
Induced pluripotent stem cells (iPSCs) offer huge promise and potential in the creation of patient-specific stem cells for modeling human diseases,...
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Application of Induced Pluripotent Stem Cells in Malignant Solid Tumors
In the past decade, induced pluripotent stem cells (iPSCs) technology has significantly progressed in studying malignant solid tumors. This...
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Differentiation of Human Fetal Muscle Stem Cells from Induced Pluripotent Stem Cells
Most muscular dystrophies are the result of genetic disorders. There is currently no effective treatment for these progressive diseases except...
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The migration pattern of cells during the mesoderm and endoderm differentiation from human pluripotent stem cells
Gastrulation is the first major differentiation process in animal embryos. However, the dynamics of human gastrulation remain mostly unknown owing to...
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The impact of induced pluripotent stem cells in animal conservation
It is widely acknowledged that we are currently facing a critical tip** point with regards to global extinction, with human activities driving us...
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Differentiation of Hepatic Stellate Cells from Pluripotent Stem Cells
Hepatic stellate cells (HSCs) are non-parenchymal cells with a mesenchymal origin involved in vitamin A storage and extracellular matrix (ECM)...
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Induction of Primordial Germ Cell-Like Cells from Rat Pluripotent Stem Cells
In vitro induction of primordial germ cell like-cells (PGCLCs) from pluripotent stem cells (PSCs) is a robust method that will contribute to...
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Induction of Human Extraembryonic Mesoderm Cells from Naive Pluripotent Stem Cells
The human extraembryonic mesoderm (EXM) is an important tissue in the postimplantation embryo which is specified before gastrulation in primates but...
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Establishing extended pluripotent stem cells from human urine cells
BackgroundExtended pluripotent stem cells (EPSCs) can contribute to both embryonic and trophectoderm-derived extraembryonic tissues. Therefore, EPSCs...
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Mesenchymal stem/stromal cells from human pluripotent stem cell-derived brain organoid enhance the ex vivo expansion and maintenance of hematopoietic stem/progenitor cells
BackgroundMesenchymal stem/stromal cells (MSCs) are of great therapeutic value due to their role in maintaining the function of hematopoietic...
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Induced Pluripotent Stem (iPS) Cells Methods and Protocols
This extensive new edition presents protocols reflecting the great strides made in the study of induced pluripotent stem (iPS) cells. The collection...
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Reconstitution of Human Prospermatogonial Development from Human-Induced Pluripotent Stem Cells
There is a scarcity of information regarding the molecular mechanisms underlying human germ cell development due to limitations in obtaining the...
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The Epiblast and Pluripotent Stem Cell Lines
All somatic cells develop from the epiblast, which occupies the upper layer of two-layered embryos and in most mammals is formed after the...
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A rapid and stable spontaneous reprogramming system of Spermatogonial stem cells to Pluripotent State
BackgroundThe scarcity of pluripotent stem cells poses a major challenge to the clinical application, given ethical and biosafety considerations....
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Mimicking Islet Development with Human Pluripotent Stem Cells
The development of functional beta cells from human pluripotent stem cells (PSCs) offers a promising approach for treating type 1 diabetes (T1D)....
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Generating hematopoietic cells from human pluripotent stem cells: approaches, progress and challenges
Human pluripotent stem cells (hPSCs) have been suggested as a potential source for the production of blood cells for clinical application. In two...
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Induced Pluripotent Stem Cells and Human Disease Methods and Protocols
This detailed volume presents a series of protocols that are representative of recent developments and improvements in induced pluripotent stem cells...
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Equine Induced Pluripotent Stem Cell Culture
Groundbreaking work by Takahashi and Yamanaka in 2006 demonstrated that non-embryonic cells can be reprogrammed into pluripotent stem cells (PSCs) by...