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Isolation of Perivascular Mesenchymal Progenitor Cells from Human Adipose Tissue by Flow Cytometry
Perivascular cells represent an in vivo counterpart of mesenchymal stromal/stem cells that populate the outer layer of blood vessels. Pericytes in...
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Interleukin-10 deficiency induces thoracic perivascular adipose tissue whitening and vascular remodeling
Perivascular adipose tissue (PVAT) is an adipose layer, surrounding blood vessels, with a local modulatory role. Interleukin-10 (IL-10) has been...
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Immunophenotype of Mesenchymal Stem Cells Derived from Epicardial and Perivascular Adipose Tissue in Patients with Cardiovascular Diseases
AbstractThe work was aimed to evaluate the immunophenotype of adipose tissue stem cells isolated from epicardial and perivascular fat depots in...
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Endothelium-Independent Anti-Contractile Effect of Rat Aorta Perivascular Adipose Tissue at Control and Metabolic Disorders Induced by the Cafe Diet
AbstractThe use of high-calorie nutrition can lead to morpho-functional changes of the vascular bed that have clinical importance, however, the...
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Whole-Mount Imaging of Adipose Tissue Macrophages
The adipose tissue comprises highly heterogeneous macrophage populations, which play critical roles in the regulation of adipose tissue function and...
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Evaluation of Proinflammatory Cytokines in Adipose Tissue of Hypertensive Lyon Rats
AbstractHypertension is a major risk factor for stroke and metabolic heart disease characterized by elevated systemic arterial blood pressure (BP),...
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Defining the lineage of thermogenic perivascular adipose tissue
Brown adipose tissue can expend large amounts of energy, and therefore increasing its size or activity is a promising therapeutic approach to combat...
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Adipose tissue as a linchpin of organismal ageing
Ageing is a conserved biological process, modulated by intrinsic and extrinsic factors, that leads to changes in life expectancy. In humans, ageing...
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Evaluation of the usefulness of determining the level of selected inflammatory biomarkers and resistin concentration in perivascular adipose tissue and plasma for predicting postoperative atrial fibrillation in patients who underwent myocardial revascularisation
BackgroundThe development of coronary artery disease (CAD) is related to the impaired quantity and composition of inflammatory proteins found in...
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Characteristic and fate determination of adipose precursors during adipose tissue remodeling
Adipose tissues are essential for actively regulating systemic energy balance, glucose homeostasis, immune responses, reproduction, and longevity....
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Morphological Peculiarities of Innervation of Rat Epicardial Adipose Tissue in Early Postnatal Ontogenesis
AbstractThe study aimed to analyze the structure and innervation of the epicardial adipose tissue (EAT) in the aortic-pulmonary region of the rat...
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Perivascular mesenchymal cells control adipose-tissue macrophage accrual in obesity
Chronic low-grade white adipose tissue (WAT) inflammation is a hallmark of metabolic syndrome in obesity. Here, we demonstrate that a subpopulation...
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Serum- and xeno-free culture of human umbilical cord perivascular cells for pediatric heart valve tissue engineering
BackgroundConstructs currently used to repair or replace congenitally diseased pediatric heart valves lack a viable cell population capable of...
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Adipose tissue aging: mechanisms and therapeutic implications
Adipose tissue, which is the crucial energy reservoir and endocrine organ for the maintenance of systemic glucose, lipid, and energy homeostasis,...
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PDGFRβ + cell HIF2α is dispensable for white adipose tissue metabolic remodeling and hepatic lipid accumulation in obese mice
BackgroundObesity is associated with extensive white adipose tissue (WAT) expansion and remodeling. Healthy WAT expansion contributes to the...
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Research update of adipose tissue-based therapies in regenerative dermatology
Mesenchymal stromal/stem cells (MSCs) have a spontaneous propensity to support tissue homeostasis and regeneration. Among the several sources of...
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Bone Marrow Adipose Tissue: Regulation of Osteoblastic Niche, Hematopoiesis and Hematological Malignancies
Bone marrow adipose tissue (BMAT) creates a specific microniche within multifunctional bone marrow (BM) ecosystem which imposes changes in...
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Adtrp regulates thermogenic activity of adipose tissue via mediating the secretion of S100b
Brown and beige adipose tissues dissipate chemical energy in the form of heat to maintain your body temperature in cold conditions. The impaired...
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PITPNC1 promotes the thermogenesis of brown adipose tissue under acute cold exposure
Brown adipose tissue (BAT) plays an essential role in non-shivering thermogenesis. The phosphatidylinositol transfer protein, cytoplasmic 1 (PITPNC1)...
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The metabolic and functional roles of sensory nerves in adipose tissues
Homeostatic regulation of adipose tissue is critical for the maintenance of energy balance and whole-body metabolism. The peripheral nervous system...
