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Predicting horizontal gene transfers with perfect transfer networks
BackgroundHorizontal gene transfer inference approaches are usually based on gene sequences: parametric methods search for patterns that deviate from...
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Perfect Crystals: microgravity capillary counterdiffusion crystallization of human manganese superoxide dismutase for neutron crystallography
The NASA mission Perfect Crystals used the microgravity environment on the International Space Station (ISS) to grow crystals of human manganese...
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Multiallelic Maximal Perfect Haplotype Blocks with Wildcards via PBWT
Computing maximal perfect blocks of a given panel of haplotypes is a crucial task for efficiently solving problems such as polyploid haplotype...
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Benchmarking short and long read polishing tools for nanopore assemblies: achieving near-perfect genomes for outbreak isolates
BackgroundOxford Nanopore provides high throughput sequencing platforms able to reconstruct complete bacterial genomes with 99.95% accuracy. However,...
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Wings are not perfect: increased wing asymmetry in a tropical butterfly as a response to forest fragmentation
Habitat fragmentation and ecosystem changes have the potential to affect animal populations in different ways. To effectively monitor these changes,...
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A dynamic state variable model suggests a stronger effect of age than individual energetic state on reproductive allocation in burying beetles
Evolutionary fitness is determined by how an organism allocates energy, or other limited resources, to reproduction during its lifetime. For...
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Mechanical state transitions in the regulation of tissue form and function
From embryonic development, postnatal growth and adult homeostasis to reparative and disease states, cells and tissues undergo constant changes in...
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Comparative modeling of fluorescence and P700 induction kinetics for alga Scenedesmus sp. obliques and cyanobacterium Synechocystis sp. PCC 6803. Role of state 2–state 1 transitions and redox state of plastoquinone pool
The model of thylakoid membrane system (T-M model) (Belyaeva et al. Photosynth Res 2019, 140:1–19) has been improved in order to analyze the...
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Predicting gene expression state and prioritizing putative enhancers using 5hmC signal
BackgroundLike its parent base 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC) is a direct epigenetic modification of cytosines in the context...
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Morphodynamical cell state description via live-cell imaging trajectory embedding
Time-lapse imaging is a powerful approach to gain insight into the dynamic responses of cells, but the quantitative analysis of morphological changes...
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Excitation transfer and quenching in photosystem II, enlightened by carotenoid triplet state in leaves
Accumulation of carotenoid (Car) triplet states was investigated by singlet–triplet annihilation, measured as chlorophyll (Chl) fluorescence...
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Induction of a torpor-like hypothermic and hypometabolic state in rodents by ultrasound
Torpor is an energy-conserving state in which animals dramatically decrease their metabolic rate and body temperature to survive harsh environmental...
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CryoEM reveals that ribosomes in microsporidian spores are locked in a dimeric hibernating state
Translational control is an essential process for the cell to adapt to varying physiological or environmental conditions. To survive adverse...
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Excited-state observation of active K-Ras reveals differential structural dynamics of wild-type versus oncogenic G12D and G12C mutants
Despite the prominent role of the K-Ras protein in many different types of human cancer, major gaps in atomic-level information severely limit our...
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Pseudomonas putida and its close relatives: mixing and mastering the perfect tune for plants
AbstractPlant growth–promoting rhizobacteria (PGPR) are a group of microorganisms of utmost interest in agricultural biotechnology for their...
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Evaluation of biotechnological processing through solid-state fermentation of oilseed cakes on extracts bioactive potential
Oilseed cakes (OC) are natural sources of lignocellulosic biomass, produced every year in large amounts. In addition to their main applications as...
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Western Blot Processing Optimization: The Perfect Blot
Western blot processing is a well-established procedure that includes protein extraction from tissues and cells, gel electrophoresis separation,...
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Multi-locus sequence ty**, antimicrobials resistance and virulence profiles of Salmonella enterica isolated from bovine carcasses in Minas Gerais state, Brazil
The aim of this study was to identify virulence and antimicrobial resistance profiles and determine the sequence type (ST) by multilocus sequence...
