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Growth, pathogenicity and sexual fertility of the African tree pathogen Ceratocystis albifundus
The African fungus Ceratocystis albifundus does not cause disease symptoms on its wide range of native woody hosts. However, on non-native Acacia...
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An Introduction to Microbial Genomic Islands for Evolutionary Adaptation and Pathogenicity
Genomic islands (GEIs) play a vital role in the bacteria’s evolutionary adaptation and pathogenicity. GEIs are the unusual region located in the... -
A computational approach to biological pathogenicity
The current pandemic (COVID-19) has made evident the need to approach pathogenicity from a deeper and more systematic perspective that might lead to...
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dbCNV: deleteriousness-based model to predict pathogenicity of copy number variations
BackgroundCopy number variation (CNV) is a type of structural variation, which is a gain or loss event with abnormal changes in copy number. Methods...
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RExPRT: a machine learning tool to predict pathogenicity of tandem repeat loci
Expansions of tandem repeats (TRs) cause approximately 60 monogenic diseases. We expect that the discovery of additional pathogenic repeat expansions...
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Phylogeny, distribution, and pathogenicity of fusarioid fungi associated with chickpea wilt in Sinaloa and Sonora, Mexico
Wilt disease complex is the most important disease of chickpeas ( Cicer arietinum L.) in the production areas from Mexico. Disease symptoms include...
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Identification and pathogenicity of Fusarium spp. associated with tea wilt in Zhejiang Province, China
BackgroundTea is one of the most widely consumed beverages in the world, with significant economic and cultural value. However, tea production faces...
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Csn5 inhibits autophagy by regulating the ubiquitination of Atg6 and Tor to mediate the pathogenicity of Magnaporthe oryzae
Csn5 is subunit 5 of the COP9 signalosome (CSN), but the mechanism by which it strictly controls the pathogenicity of pathogenic fungi through...
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Molecular mechanisms of Ustilaginoidea virens pathogenicity and their utilization in disease control
Rice false smut, caused by Ustilaginoidea virens , is one of the most important diseases in rice. The disease not only causes significant yield losses...
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The histone deacetylase UvHOS2 regulates vegetative growth, conidiation, ustilaginoidin synthesis, and pathogenicity in Ustilaginoidea virens
Ustilaginoidea virens causes rice false smut, one of the most devastating rice diseases. The pathogen produces various types of mycotoxins, such as...
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GBA1 in Parkinson’s disease: variant detection and pathogenicity scoring matters
BackgroundGBA1 variants are the strongest genetic risk factor for Parkinson’s disease (PD). However, the pathogenicity of GBA1 variants concerning...
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Identification and pathogenicity analysis of Fusarium spp. on peach in China
BackgroundVascular system is affected by diseases that can seriously damage plant health by inducing browning and death of branches. This study aimed...
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Diversity and Pathogenicity of the Fusarium Fungi Occurred in Soybean Mycobiota
AbstractThe aim of the present study was to reveal the species composition of Fusarium fungi found in soybean mycobiota from the various regions of...
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Rho2 involved in development, stress response and pathogenicity of Fusarium oxysporum
Rho GTPases regulate the activity of cell wall biosynthesis, actin assembly and polar cell secretion. However, the function of Rho GTPase in...
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Comparative pathogenicity of SARS-CoV-2 Omicron subvariants including BA.1, BA.2, and BA.5
The unremitting emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants necessitates ongoing control measures. Given its...
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PDIVAS: Pathogenicity predictor for Deep-Intronic Variants causing Aberrant Splicing
BackgroundDeep-intronic variants that alter RNA splicing were ineffectively evaluated in the search for the cause of genetic diseases. Determination...
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The implication of viability and pathogenicity by truncated lipopolysaccharide in Yersinia enterocolitica
AbstractThe fast envelope stress responses play a key role in the transmission and pathogenesis of Yersinia enterocolitica , one of the most common...
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Protein kinase C is required for the pathogenicity of Setosphaeria turcica on maize
Northern corn leaf blight caused by Setosphaeria turcica is one of the most important fungal diseases of maize. We previously cloned and analyzed the...
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UvSnx4 is required for conidiation, pathogenicity and stress responses by regulating mitophagy and macroautophagy in Ustilaginoidea virens
Rice false smut disease, caused by the biotrophic fungus Ustilaginoidea virens , threatens rice production and quality. SNX family proteins have a...
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MoScd2 is involved in appressorium formation and pathogenicity via the Pmk1 MAPK pathway in Magnaporthe oryzae
Rice blast, known as rice “cancer”, is caused by Magnaporthe oryzae and is particularly serious in Asian and African rice regions. China is also a...