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Showing 1-20 of 1,380 results
  1. SHMT2 promotes papillary thyroid cancer metastasis through epigenetic activation of AKT signaling

    Cancer cells alter their metabolism and epigenetics to support cancer progression. However, very few modulators connecting metabolism and epigenetics...

    Min Sun, Mingjian Zhao, ... Xuetian Yue in Cell Death & Disease
    Article Open access 25 January 2024
  2. METTL16 inhibits papillary thyroid cancer tumorigenicity through m6A/YTHDC2/SCD1-regulated lipid metabolism

    Papillary thyroid carcinoma (PTC) stands as the leading cancer type among endocrine malignancies, and there exists a strong correlation between...

    Qiang Li, Yaju Wang, ... Lei Zhou in Cellular and Molecular Life Sciences
    Article Open access 09 February 2024
  3. Tumor microbiome diversity influences papillary thyroid cancer invasion

    Papillary thyroid carcinoma (PTC) has a high incidence, and its proper treatment remains challenging. Therefore, identifying PTC progression markers...

    Lijuan Yuan, ** Yang, ... Guoqiang Bao in Communications Biology
    Article Open access 24 August 2022
  4. CD73 mitigates ZEB1 expression in papillary thyroid carcinoma

    Background

    ZEB1, a core transcription factor involved in epithelial-mesenchymal transition (EMT), is associated with aggressive cancer cell behavior,...

    Samlai Vedovatto, Fernanda Dittrich Oliveira, ... Guido Lenz in Cell Communication and Signaling
    Article Open access 22 February 2024
  5. The Inverse Association of Serum Magnesium with Papillary Thyroid Cancer in Thyroid Nodules: a Cross-Sectional Survey Based on Thyroidectomy Population

    Magnesium is considered to play a role in preventing cancer. However, the association between serum magnesium and papillary thyroid cancer (PTC)...

    Huai** Xu, **aodong Hu, ... Zhaohui Lyu in Biological Trace Element Research
    Article 13 October 2022
  6. SYVN1 modulates papillary thyroid carcinoma progression by destabilizing HMGB1

    E3 ubiquitin ligase synoviolin (SYVN1) has been reported to participate in many human cancers. This study aimed to investigate SYVN1’s roles and...

    Fei Duan, Fanli Kong, ... Hongbing Liu in Cell Division
    Article Open access 28 April 2024
  7. Identifying potential breath biomarkers for early diagnosis of papillary thyroid cancer based on solid-phase microextraction gas chromatography-high resolution mass spectrometry with metabolomics

    Introduction

    Thyroid cancer incidence rate has increased substantially worldwide in recent years. Fine needle aspiration biopsy (FNAB) is currently...

    Lan Li, **nxin Wen, ... Yixiang Duan in Metabolomics
    Article 21 May 2024
  8. LncRNA GLTC targets LDHA for succinylation and enzymatic activity to promote progression and radioiodine resistance in papillary thyroid cancer

    Dysregulation of long noncoding RNAs (lncRNAs) has been associated with the development and progression of many human cancers. Lactate dehydrogenase...

    Liang Shi, Rui Duan, ... Xue Xue in Cell Death & Differentiation
    Article 08 April 2023
  9. Mcl-1 mediates intrinsic resistance to RAF inhibitors in mutant BRAF papillary thyroid carcinoma

    Papillary thyroid carcinoma (PTC) is the most frequent form of thyroid cancer. PTC commonly presents with mutations of the serine/threonine kinase...

    Maria R. Cavallo, Jacob C. Yo, ... Edward J. Hartsough in Cell Death Discovery
    Article Open access 15 April 2024
  10. NR4A1 promotes LEF1 expression in the pathogenesis of papillary thyroid cancer

    The morbidity of papillary thyroid cancer (PTC) is on the rise, but its pathogenesis is still poorly understood. NR4A1 is a transcription factor...

    Cen Jiang, Jianli He, ... **ke Cheng in Cell Death Discovery
    Article Open access 02 February 2022
  11. Identification of potential biomarkers for papillary thyroid carcinoma by comprehensive bioinformatics analysis

    To perform bioinformatics analysis on the papillary thyroid carcinoma (PTC) gene chip dataset to explore new biological markers for PTC. The gene...

    Min Liao, Zhen Wang, ... Bo Qiu in Molecular and Cellular Biochemistry
    Article 12 January 2023
  12. Proteomics profiling for the global and acetylated proteins of papillary thyroid cancers

    Background

    Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy cancer among the malignancies of thyroid. Despite of wide usages...

    Wei Wei, Yuezhang Wu, ... **ao-** Dong in Proteome Science
    Article Open access 26 April 2023
  13. Autophagy inhibition contributes to epigallocatechin-3-gallate-mediated apoptosis in papillary thyroid cancer cells

    Background

    Epigallocatechin-3-gallate is a natural polyphenolic compound that induces apoptosis in papillary thyroid cancer cells. However, its...

    Ling Bu, Tingting Zheng, ... Xuefeng Wang in Molecular & Cellular Toxicology
    Article 25 August 2021
  14. Fasting regulates mitochondrial function through lncRNA PRKCQ-AS1-mediated IGF2BPs in papillary thyroid carcinoma

    Recurring evidence suggests that fasting has extensive antitumor effects in various cancers, including papillary thyroid carcinoma (PTC). However,...

    ** Zhang, Yong Zhong, ... Zhongwei Lv in Cell Death & Disease
    Article Open access 14 December 2023
  15. Using CRISPR/Cas9 to Edit a Thyroid Cancer Cell Line

    Thyroid cancer is the most prevalent endocrine malignancy, comprising multiple types of cancer, with distinct clinical-pathological characteristics....
    Cesar Seigi Fuziwara, Edna Teruko Kimura in Genome Editing in Biomedical Sciences
    Chapter 2023
  16. KLHL14 is a tumor suppressor downregulated in undifferentiated thyroid cancer

    KLHL14 is a substrate-binding subunit of Cullin-RING ligase 3 ubiquitin ligase complex, highly enriched in thyroid since early embryonic development,...

    Matteo Esposito, Antonella Migliaccio, ... Gabriella De Vita in Cell Death Discovery
    Article Open access 22 June 2024
  17. CircRNA circTIAM1 promotes papillary thyroid cancer progression through the miR-646/HNRNPA1 signaling pathway

    Papillary thyroid cancer (PTC) is a common endocrine tumor with a rapidly increasing incidence in recent years. Although the majority of PTCs are...

    Deguang Zhang, Li Tao, ... Junjie Chu in Cell Death Discovery
    Article Open access 12 January 2022
  18. Three-dimensional genome landscape comprehensively reveals patterns of spatial gene regulation in papillary and anaplastic thyroid cancers: a study using representative cell lines for each cancer type

    Background

    Spatial chromatin structure is intricately linked with somatic aberrations, and somatic mutations of various cancer-related genes, termed...

    Linlin Zhang, Miaomiao Xu, ... Hui Wang in Cellular & Molecular Biology Letters
    Article Open access 06 January 2023
  19. Maslinic acid induces apoptosis in thyroid cancer cells via endoplasmic reticulum stress

    Background

    Thyroid cancer is one of the most common malignant tumors of the endocrine system. Studies have demonstrated that maslinic acid (MA) has a...

    **g Zhu, **hui Tu, ... Fengling Chen in Molecular & Cellular Toxicology
    Article 12 December 2023
  20. Neutrophil diversity is associated with T-cell immunity and clinical relevance in patients with thyroid cancer

    Neutrophil heterogeneity is involved in autoimmune diseases, sepsis, and several cancers. However, the link between neutrophil heterogeneity and...

    Seong Eun Lee, Bon Seok Koo, ... Yea Eun Kang in Cell Death Discovery
    Article Open access 08 May 2024
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